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557 articles

July 202624

Clinical ResearchPulmonology

Cryobiopsy versus conventional bronchoscopic sampling for peripheral pulmonary lesions (Cryo-RCT): an open-label, parallel-group, randomised trial.

This open-label, parallel-group, randomised trial evaluated the diagnostic yield of cryobiopsy versus conventional bronchoscopic sampling in 627 patients with peripheral pulmonary lesions.

Lancet Respir MedJul 29, 2026Read summary
Clinical ResearchPulmonology

Detection rate and risk factors of carotid atherosclerotic plaque in patients with obstructive sleep apnea syndrome: A systematic review and meta-analysis.

This systematic review and meta-analysis examined carotid atherosclerotic plaque (CAP) detection and associated factors in patients with obstructive sleep apnea syndrome (OSAS), including 37 studies.

Heart LungJul 29, 2026Read summary
Clinical ResearchCardiology

Conical Mesh-Disc Catheter-Directed Mechanical Thrombectomy for Acute Pulmonary Embolism: A Nationwide Prospective, Multicenter, Single-Arm Study.

This nationwide prospective, multicenter, single-arm study assessed a conical mesh-disc catheter-directed mechanical thrombectomy system in adults with acute pulmonary embolism, right ventricular dilation, and stable…

Ann Vasc SurgJul 29, 2026Read summary
Clinical ResearchAllergy & Immunology

Biologics and Selected Upper- and Lower-Airway Outcomes in AERD Subgroups: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed biologics versus placebo for selected upper- and lower-airway outcomes in patients with aspirin-exacerbated respiratory disease (AERD) represented in randomized…

J Allergy Clin Immunol PractJul 29, 2026Read summary
Clinical ResearchCardiologyOpen access

"Two-For-One": 4D Cardiac and Pulmonary MR Imaging From a Single Acquisition Using bSTAR.

This clinical trial evaluated a novel imaging technique, bSTAR, for generating 4D cardiac and pulmonary images from a single acquisition in 10 healthy volunteers and 12 patients with cardiomyopathy or lung diseases.

Magn Reson MedJul 28, 2026Read summary
Clinical ResearchRheumatology

Association between obstructive sleep apnea and gout risk, and the urate-lowering effects of continuous positive airway pressure: A meta-analysis.

This meta-analysis examined the association between obstructive sleep apnea (OSA) and gout risk, as well as the effects of continuous positive airway pressure (CPAP) on serum uric acid levels.

Sleep MedJul 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

SKYSCRAPER-01: Tiragolumab in Combination With Atezolizumab in Previously Untreated PD-L1-High, Locally Advanced, Unresectable or Metastatic Non-Small Cell Lung Cancer.

The SKYSCRAPER-01 study evaluated tiragolumab combined with atezolizumab in 521 patients with untreated, locally advanced unresectable or metastatic PD-L1-high non-small cell lung cancer.

J Clin OncolJul 27, 2026Read summary
Clinical ResearchPulmonology

Peri-procedural vs. post-procedural mortality after endobronchial valve treatment for severe emphysema: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the impact of endobronchial valve (EBV) treatment on mortality in patients with severe emphysema, analyzing data from six randomized controlled trials involving 819…

Expert Rev Med DevicesJul 27, 2026Read summary
Case ReportInfectious Diseases

Klebsiella pneumoniae septic pulmonary embolism from renal vein thrombosis.

A 47-year-old woman with untreated diabetes presented with urinary symptoms, fever, abdominal pain, and hypoxemia. Blood and urine cultures confirmed Klebsiella pneumoniae, with persistent bacteremia despite meropenem…

Int J Infect DisJul 26, 2026Read case
Clinical ResearchPhysical Medicine & Rehabilitation

Multidimensional Factors Influencing the Implementation of Early Mobilization in Critically Ill Patients From Healthcare Providers' Perspectives: A Systematic Review.

This qualitative systematic review and meta-synthesis examined ICU healthcare providers’ experiences and perspectives on implementing early mobilization. It included 34 studies from 13 countries, involving 699 providers.

J Adv NursJul 26, 2026Read summary
Clinical ResearchPulmonologyOpen access

Respiratory effects of recruitment maneuvers according to lung recruitability assessed by electrical impedance tomography in patients with acute respiratory distress syndrome.

This randomized controlled trial assessed the effects of recruitment maneuvers (RM) followed by EIT-guided PEEP titration in 50 patients with moderate-to-severe ARDS.

J Clin Monit ComputJul 24, 2026Read summary
Case ReportInfectious Diseases

Fatal septic shock due to PVL-positive Staphylococcus aureus necrotizing pneumonia: autopsy findings and systematic review of the literature.

A previously healthy 58-year-old man presented with acute respiratory symptoms and quickly progressed to severe respiratory failure and septic shock, leading to death within 24 hours of hospital admission.

Leg Med (Tokyo)Jul 23, 2026Read case
Clinical ResearchPediatrics

Meta-analysis of prostacyclin therapy for persistent pulmonary hypertension with congenital diaphragmatic hernia.

This meta-analysis evaluated the efficacy and safety of prostacyclin therapy for persistent pulmonary hypertension in infants with congenital diaphragmatic hernia, analyzing data from nine studies involving 7009…

J Pediatr SurgJul 23, 2026Read summary
Clinical ResearchPulmonology

Effectiveness of self-management digital interventions in improving health-related outcomes in patients with chronic obstructive pulmonary disease: An umbrella review.

This umbrella review assessed the effectiveness of self-management digital interventions on health outcomes in adults with chronic obstructive pulmonary disease (COPD).

PulmonologyJul 22, 2026Read summary
Case ReportEmergency Medicine

Cardiopulmonary bone cement embolism after Percutaneous Kyphoplasty: a case series.

This report details five patients who developed cement-induced intracardiopulmonary embolism following percutaneous kyphoplasty.

Am J Emerg MedJul 22, 2026Read case
Clinical ResearchPulmonology

Developing low-carbon metered-dose inhalers: effects of propellant HFA-152a on mucociliary clearance and bronchoconstriction in two Phase 1 randomised trials.

This study evaluated the effects of the low-global warming potential propellant HFA-152a compared to HFA-134a on mucociliary clearance and bronchoconstriction in two Phase 1 randomized trials.

Respir MedJul 21, 2026Read summary
Clinical ResearchPediatrics

A Randomized Trial to Increase Outpatient Asthma Referrals Upon Pediatric Emergency Department Discharge.

This prospective randomized controlled trial assessed whether the Pediatric Asthma Control and Communication Instrument for the Emergency Department (PACCI-ED) increased outpatient asthma referrals after emergency…

Pediatr Emerg CareJul 21, 2026Read summary
Case ReportOncology (Medical)

PSMA-avid Pleural Solitary Fibrous Tumor Incidentally Detected on [ 18 F] Piflufolastat PSMA PET/CT.

An 81-year-old man with biopsy-proven high-risk prostate cancer (PCa) underwent staging with [ 18 F]piflufolastat PET/CT. Imaging showed intense uptake in the prostate gland and an incidental PSMA-avid pleural lesion in…

Clin Nucl MedJul 20, 2026Read case
Clinical ResearchPulmonologyOpen access

Clinical Remission with FF/UMEC/VI Versus ICS/LABA in Uncontrolled Asthma: The PERFORM Pragmatic Randomized Controlled Trial.

The PERFORM trial, a pragmatic randomized controlled trial, evaluated the effectiveness of fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) in…

Adv TherJul 20, 2026Read summary
Clinical ResearchPulmonology

Cough Assistance Techniques in Adolescents and Young Adults with Neuromuscular Diseases Using Home Noninvasive Ventilatory Support: A Preliminary Cross-Sectional Physiological Study.

This cross-sectional physiological study evaluated cough assistance techniques in adolescents and young adults with neuromuscular diseases using home noninvasive ventilation.

NeuroRehabilitationJul 18, 2026Read summary
Case ReportPulmonology

Marked IgE elevation and eosinophilia in a COPD patient ultimately diagnosed with mycobacterium intracellulare pulmonary disease.

A 65-year-old man with COPD presented with persistent eosinophilia and significantly elevated total IgE levels. Initial evaluations for allergic diseases were negative.

Diagn Microbiol Infect DisJul 17, 2026Read case
Clinical ResearchAnesthesiology

Remimazolam vs. propofol anaesthesia for delirium in older patients recovering from lung resections: a randomised non-inferiority trial.

This randomised non-inferiority trial compared remimazolam with propofol anaesthesia in patients aged 65 years or older undergoing lung resection.

AnaesthesiaJul 17, 2026Read summary
Clinical ResearchPulmonology

Pulmonary MRI in Interstitial Lung Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis of observational studies assessed pulmonary MRI for detecting interstitial lung disease (ILD), using CT as the primary reference standard.

J Magn Reson ImagingJul 17, 2026Read summary
Clinical ResearchPulmonology

Systematic review of prognostic scores and individual predictor variables for short-term mortality after acute pulmonary embolism.

This systematic review evaluated prognostic models and individual predictors for short-term mortality in patients with acute pulmonary embolism (PE), analyzing 314 studies involving 2,495,115 patients.

PulmonologyJul 16, 2026Read summary

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