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1303 articles
September 202624
Default mode network functional connectivity following treatment with conventional antidepressants and (es)ketamine in major depressive disorder: A systematic review.
This systematic review examined changes in default mode network resting-state functional connectivity (DMN rsFC) after conventional antidepressants or (es)ketamine in people with major depressive disorder, including…
Medically Unexplained Symptoms: A Systematic Umbrella Review of Current Terminology and Reported Rationales.
This systematic umbrella review examined the terminology surrounding Medically Unexplained Symptoms (MUS) across 422 reviews. It identified 111 distinct terms, with 'functional' being the most common (n=233).
Insights from changes in NDEV biomarkers of metabolism: effects of PPARγ and GLP1 receptor agonists on brain metabolism.
This randomized controlled trial examined the effects of pioglitazone (PPARγ agonist) and liraglutide (GLP1 receptor agonist) on central nervous system insulin signaling in participants with unremitted depression and…
Drawing and visual art interventions for anxiety in children aged 5-12: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated the impact of drawing and visual art interventions on anxiety in children aged 5-12 years.
Prediction Models for In-Hospital Delirium Using Routinely Collected Electronic Health Record Data: Systematic Review.
This systematic review evaluated prediction models for in-hospital delirium using electronic health record data, analyzing 29 studies.
Problematic Reliance on Generative AI in an Anxious Young Adult: Case Report.
A woman in her mid-20s with generalized anxiety disorder and major depressive disorder developed a functional dependence on generative AI tools, particularly ChatGPT, for cognitive and interpersonal tasks.
Virtual Reality-Assisted Therapy Compared to Cognitive Behavioral Therapy for Patients With Treatment-Resistant Schizophrenia: Assessor-Blind Randomized Controlled Trial.
This assessor-blind randomized controlled trial compared virtual reality-assisted therapy (VRT) to cognitive behavioral therapy (CBT) in 136 adults with treatment-resistant schizophrenia and persistent auditory verbal…
Endotype-informed therapy and effects on illness perception and psychological health in patients with chest pain and no obstructive coronary artery disease.
The CorCMR trial, a multicenter randomized controlled trial, evaluated the impact of non-invasive stress perfusion cardiovascular magnetic resonance (CMR) on illness perception and psychological health in 250 patients…
Changes in dyadic emotional flexibility and expressivity during parent-child interactions following successful treatment of child anxiety.
This randomized controlled trial examined changes in dyadic emotional flexibility and expressivity during parent-child interactions following treatment for child anxiety in 116 children.
Sleep quality and quality of life in people with non-affective psychosis: A systematic review of relationships across phases and age groups.
This PRISMA-guided systematic review examined associations between sleep quality and quality of life (QoL) in people with non-affective psychosis across illness phases and age groups.
Psychological interventions for harmful gambling: Systematic review and network meta-analysis.
This systematic review and network meta-analysis compared psychological interventions for harmful gambling across 52 randomized controlled trials involving 9013 participants and 14 intervention classes.
Safety and tolerability of temporal interference stimulation in humans: A systematic review and meta-analysis of an emerging deep neuromodulation technology.
This systematic review and meta-analysis assessed safety and tolerability of temporal interference stimulation (TIS) in human studies.
How common is alcohol use disorder in posttraumatic stress disorder? A systematic review, meta-analysis, and moderator analysis.
This systematic review and meta-analysis examined alcohol use disorder (AUD) prevalence among adults with posttraumatic stress disorder (PTSD), using 20 observational studies with 185,432 participants.
Early-stage trajectories of social-occupational functioning and long-term functional outcome prediction in early psychosis: A 12-year follow-up of the randomized controlled trial on extended early intervention.
This randomized controlled trial followed 148 participants with early psychosis over 12 years to examine early social-occupational functioning trajectories.
Non-coding RNAs and Mitochondrial Dysfunction in Alzheimer's Disease: A Systematic Review.
This systematic review examined the role of non-coding RNAs (ncRNAs) in mitochondrial dysfunction associated with Alzheimer's disease (AD).
Deep brain stimulation for Tourette syndrome: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of deep brain stimulation (DBS) for refractory Tourette syndrome (TS) across various brain targets.
Is appearance-related social comparison a causal mechanism underlying appearance-related psychopathology among young adult women? An experimental test.
This randomized controlled trial examined the impact of appearance-related social comparison (ARSC) fading on young adult women with high appearance concerns.
Ketamine attenuates habenula activity in response to aversive outcomes during Pavlovian learning.
In a randomized, placebo-controlled translational study, 70 healthy adults received ketamine (0.5 mg/kg) or placebo (NaCl 0.9%) and completed an aversive Pavlovian conditioning task during 7-tesla functional…
Effects of an algorithmically enhanced personalized music-based intervention in patients with dementia.
This randomized controlled trial evaluated an AI-driven, personalized music intervention in 20 people with mild dementia, including Alzheimer’s disease.
Five-year outcomes in a randomised controlled trial of prolonged exposure therapy and supportive counselling for post-traumatic stress disorder in adolescents: a task-shifted intervention.
This randomized controlled trial evaluated the long-term effectiveness of prolonged exposure therapy (PE-A) and supportive counselling (SC) for adolescents with PTSD, with 63 participants followed for 60 months.
Isolated physical activity programs during pregnancy and postpartum: Meta-analysis of randomized trials with usual-care controls on depressive and anxiety symptoms.
This meta-analysis evaluated the effects of isolated physical activity interventions on depressive and anxiety symptoms in pregnant and postpartum women. Seventeen randomized controlled trials were included.
Risk of neurodevelopmental disorders associated with paternal use of valproate during spermatogenesis: a living meta-analysis-version 1.
This living meta-analysis evaluated the association between paternal use of valproate during spermatogenesis and the risk of neurodevelopmental disorders (NDDs) in offspring, compared to lamotrigine or levetiracetam.
Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress: Post Hoc Analysis of a Phase 3, Randomized, Double-Blind Trial.
This post hoc analysis of a phase 3 randomized controlled trial evaluated the efficacy of adjunctive lumateperone 42 mg in patients aged 18-65 with major depressive disorder (MDD) and anxious distress.
Cognitive effects of ketamine and esketamine treatment for major depressive and bipolar disorder: a systematic review.
This systematic review assessed cognitive outcomes with ketamine and esketamine in adults with major depressive disorder, bipolar disorder, or treatment-resistant depression.
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