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1003 articles
September 202624
Infective endocarditis presenting with myocardial infarction with non-obstructive coronary arteries: A case report and literature review.
A 52-year-old male on long-term hemodialysis presented with acute chest pain, shortness of breath, and sweating. Initial ECG showed ST-segment depression, and elevated troponin I levels indicated myocardial infarction.
Helcococcus kunzii as a rare etiological agent of spondylodiscitis partially managed with oral antibiotic therapy in a patient with diabetes mellitus: a case report.
A 62-year-old man with type 1 diabetes mellitus presented with severe lumbar pain, leading to a diagnosis of spondylodiscitis confirmed by MRI.
Fatal Cutaneous Mucormycosis Initially Misdiagnosed as Necrotizing Fasciitis in an Uncontrolled Diabetic Patient: A Case Report Highlighting Diagnostic Delay.
A 64-year-old male with undiagnosed diabetes presented with altered consciousness and extensive necrotic lesions, initially diagnosed as bacterial necrotizing fasciitis.
A randomised, double-blind, placebo-controlled phase I clinical trial to evaluate the safety, tolerability and immunogenicity of three doses of an adjuvanted group B Streptococcus vaccine in older adults aged 55 to 75.
This phase I randomized controlled trial assessed the safety, tolerability, and immunogenicity of an adjuvanted group B Streptococcus vaccine (GBS-AlpN) in 90 older adults aged 55 to 75, including those with obesity…
Empirical Antibiotic Therapy for the Management of Empyema Thoracis in Children: A Systematic Review.
This systematic review evaluated empirical antibiotic therapy for empyema thoracis in children, analyzing 17 studies from various databases.
Duration of effectiveness of tuberculosis preventive treatment across various tuberculosis burden settings: a systematic review and individual-participant meta-analysis.
This systematic review and individual-participant meta-analysis pooled data from 84 128 tuberculosis-infected close contacts in 44 cohort studies across 24 countries to assess how long tuberculosis preventive treatment…
Life-threatening Streptococcus suis sepsis presenting with purpura fulminans and toxic shock-like syndrome in a patient with unknown exposure route.
A 56-year-old man with no clear history of swine contact presented with fever and altered mental status, then rapidly developed septic shock, disseminated intravascular coagulation, and purpura fulminans.
AI-Based Sepsis Prediction in Hospitalized Adults: Systematic Review, Subgroup Meta-Analysis, and Contextual Analysis of Clinical Burden.
This systematic review and meta-analysis evaluated machine learning (ML) and deep learning (DL) models for sepsis prediction in hospitalized adults, analyzing 34 studies.
A systematic review of ultrasound to predict severe disease in patients with dengue and other viral infections associated with hemorrhagic fevers.
This systematic review and meta-analysis evaluated ultrasound findings in patients with viral infections associated with hemorrhagic fevers (VaHFs) to predict severe disease.
Immunogenicity and safety of high-dose versus standard-dose quadrivalent inactivated influenza vaccine in patients living with HIV: a randomized controlled trial.
This randomized controlled trial evaluated the immunogenicity and safety of high-dose (HD) versus standard-dose (SD) quadrivalent inactivated influenza vaccine in patients living with HIV.
Switch to injectable cabotegravir-rilpivirine given every 8 weeks in adolescents living with HIV with virological suppression in sub-Saharan Africa (LATA): a randomised, open-label, multicentre, 96-week non-inferiority trial.
LATA was a randomised, open-label, multicentre, 96-week non-inferiority trial comparing injections of cabotegravir-rilpivirine every 8 weeks with daily oral dolutegravir-lamivudine-tenofovir disoproxil fumarate in…
Factors affecting hand hygiene adherence among critical care healthcare workers: A systematic review.
This PRISMA-guided systematic review examined factors associated with hand hygiene adherence among healthcare workers in intensive care units and emergency departments.
An insidious yet rapidly progressive Vibrio vulnificus bloodstream infection: A case report.
A 35-year-old man with chronic hepatitis B and decompensated cirrhosis had months of fatigue, weakness, anorexia, and dark urine, followed by abrupt fever, chills, diarrhea, profound fatigue, and rapidly worsening…
Recurrent Plasmodium falciparum Malaria after Delayed Hemolysis Induced by Artemether-Lumefantrine.
A previously healthy 39-year-old Japanese man developed Plasmodium falciparum malaria after travel to Togo and received artemether-lumefantrine in the Philippines.
Wound-Only versus Weight-Based Rabies Immunoglobulin in Post-Exposure Prophylaxis: A Quasi-Randomized Asessor Blind Non-Inferiority Trial.
This assessor-blind, quasi-randomized noninferiority trial compared wound-only with weight-based rabies immunoglobulin (RIG) administration in patients with category III rabies exposure receiving a standard three-dose…
Declining Fluoroquinolone Efficacy in Resistance-Guided Therapy for Mycoplasma genitalium : A Systematic Review and Meta-Analysis of Microbiological Cure.
This systematic review and meta-analysis assessed microbiological cure after resistance-guided therapy for Mycoplasma genitalium, pooling 11 eligible studies.
Cryptococcal meningitis with cerebrospinal fluid human immunodeficiency virus escape presenting as transient diplopia and areflexia.
A man in his early 40s with stable HIV on antiretroviral therapy presented with transient binocular diplopia and areflexia.
Clinical Perspective on Exophiala dermatitidis, A Systematic Review of Cases Reported Globally over 36 Years.
This systematic review analyzed 77 reported cases of Exophiala dermatitidis infections from 1989 to 2024, highlighting a rise in cases, particularly since 2010.
Late Diagnosis of Noonan Syndrome Presenting With Infective Endocarditis: A Multidisciplinary Challenge in an Underserved Population.
A 29-year-old woman from a rural area presented with severe respiratory distress, weight loss, and new cardiac murmurs. Examination revealed dysmorphic features indicative of Noonan syndrome.
Biofilm-producing Acinetobacter baumannii in Asia: mapping the clinical burden and antimicrobial resistance through systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence of biofilm-forming Acinetobacter baumannii in clinical isolates across Asia.
Controlling respiratory infections in long-term care facilities: A systematic review.
This systematic review synthesized experimental and quasi-experimental studies of non-pharmacological strategies to prevent or control respiratory infections in long-term care facilities.
Economic evaluation of enhanced oral care in reducing the incidence of non-ventilator hospital-acquired pneumonia.
This within-trial economic evaluation of the cluster randomised HAPPEN trial assessed enhanced oral care versus usual care across three Australian hospitals, from a hospital perspective.
Zoonotic Sarcocystis hominis and Sarcocystis heydorni in a Bovine Carcass: First Report in Portugal.
Routine inspection of a 55-month-old bovine carcass identified eosinophilic myositis-like lesions in the masseter muscles, prompting partial condemnation of the head.
BLIS study: a feasibility randomised controlled trial assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis) in adults in England.
The BLIS study was a randomized controlled trial assessing the colonization, acceptability, and feasibility of two dosing regimens of the probiotic Streptococcus salivarius K12 in adults with recurrent sore throats in…
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