Trending archive

Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.

1240 articles

September 202624

Clinical ResearchCardiology

Comparison of a Novel Occluder Versus Traditional Occluder in Atrial Septal Defect: A Randomized Trial.

This multicenter, randomized, parallel-controlled noninferiority trial compared the ReAces occluder with a traditional Amplatzer-like device in patients undergoing transcatheter closure of atrial septal defects.

J Am Heart AssocSep 18, 2026Read summary
Clinical ResearchCardiology

Association Between Rest-Activity Rhythm and Cardiovascular Disease, Cardiovascular Mortality, and All-Cause Mortality: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined associations between nonparametric rest-activity rhythm measures and cardiovascular outcomes or mortality in cohort and cross-sectional studies.

J Am Heart AssocSep 18, 2026Read summary
Clinical ResearchGastroenterology

A multidisciplinary nutritional-behavioral intervention improves weight loss and liver-related outcomes in patients with metabolic dysfunction-associated steatotic liver disease: A randomized controlled trial.

This randomized controlled trial evaluated a multidisciplinary hepatology, individualized nutrition, and cognitive behavioral support programme (Co-Co-Nut) in patients with metabolic dysfunction-associated steatotic…

Clin NutrSep 18, 2026Read summary
Clinical ResearchCardiology

Declines in plasma erythritol and improvements in cardiovascular disease risk and atherogenic lipid profiles: a 2-year randomized weight-loss dietary intervention trial.

This observational analysis of a 2-year randomized dietary-intervention trial examined whether changes in plasma polyols tracked with cardiovascular risk and lipid changes in adults with overweight or obesity.

Am J Clin NutrSep 18, 2026Read summary
Clinical ResearchVascular Surgery

Fibromuscular dysplasia and aortic involvement: a systematic review for a potential association.

This systematic review examined aortic disorders reported in people with fibromuscular dysplasia (FMD), a nonatherosclerotic arterial disease.

J HypertensSep 18, 2026Read summary
Clinical ResearchCardiology

Effect of Sacubitril/Valsartan Versus Angiotensin Receptor Blocker or Calcium Channel Blockers on Ambulatory Blood Pressure and Safety in Hypertensive Patients: A Meta-Analysis of Randomized Controlled Trials.

This meta-analysis of randomized controlled trials assessed sacubitril/valsartan versus angiotensin receptor blockers (ARBs) or calcium channel blockers (CCBs) in people with hypertension.

J Cardiovasc PharmacolSep 18, 2026Read summary
Clinical ResearchCardiology

Long-term SBP time in target and risk of cardiovascular events in older adults: a secondary analysis of the ASPREE cohort.

This observational study analyzed data from the ASPREE cohort of 16,730 older adults (mean age 74) to assess the relationship between systolic blood pressure (SBP) time in target range (TTR) and cardiovascular events.

Am J HypertensSep 17, 2026Read summary
Case ReportCardiology

Decade in hiding: chronic giant pseudoaneurysm after a coronary artery bypass grafting mimicking a double-chambered left ventricle.

A woman in her early 60s, with a history of coronary artery bypass grafting a decade prior, was found to have a cardiac opacity.

BMJ Case RepSep 17, 2026Read case
Clinical ResearchOncology (Medical)Open access

Fine-Tuning, Retrieval-Augmented Generation, and Hybrid Adaptation of Language Models for Clinical Decision-Making in Health Care: Systematic Review.

This systematic review evaluated the effectiveness of fine-tuning, retrieval-augmented generation (RAG), and hybrid adaptation strategies for transformer-based language models in clinical decision-making.

J Med Internet ResSep 17, 2026Read summary
Clinical ResearchCardiologyOpen access

Prasugrel in the management of acute coronary syndromes: a systematic review.

This systematic review evaluates the use of prasugrel in acute coronary syndromes (ACS), highlighting its pharmacological advantages over clopidogrel and ticagrelor.

DaruSep 17, 2026Read summary
Case ReportNephrologyOpen access

Highly viscous ascites prompting reconsideration of cardiorenal syndrome in a patient with advanced CKD after TAVI.

An elderly man with advanced chronic kidney disease and cardiovascular issues developed refractory pleural effusion, ascites, and peripheral edema following transcatheter aortic valve implantation.

CEN Case RepSep 17, 2026Read case
Clinical ResearchCardiologyOpen access

Impact of Cipepofol versus Propofol on Long-Term Cardiovascular Outcomes After TAVR: An Extended Follow-Up of a Randomized Trial.

This study evaluated the long-term cardiovascular outcomes of cipepofol versus propofol in patients undergoing transfemoral transcatheter aortic valve replacement (TAVR) in a randomized controlled trial.

Drug Des Devel TherSep 17, 2026Read summary
Clinical ResearchEndocrinology

Predicting the Long-Term Risk of Type 2 Diabetes and Cardiovascular Disease With Orforglipron in People With Overweight or Obesity: A Post Hoc Analysis of the ATTAIN-1 Trial.

This post hoc analysis of the Phase 3 randomised ATTAIN-1 trial assessed predicted 10-year cardiometabolic risk in adults with overweight or obesity without type 2 diabetes.

Diabetes Obes MetabSep 17, 2026Read summary
Clinical ResearchNephrology

Comparative Cardiorenal Efficacy and Safety of Finerenone, SGLT2 Inhibitors, Semaglutide and Their Combination in Diabetic Kidney Disease.

This frequentist network meta-analysis compared cardiorenal efficacy and safety of finerenone, SGLT2 inhibitors, semaglutide and their combination in adults with type 2 diabetes and diabetic kidney disease.

Diabetes Obes MetabSep 17, 2026Read summary
Clinical ResearchCardiologyOpen access

Cardiovascular risk-prediction models in cancer survivors: a meta-analysis.

This meta-analysis evaluated 34 studies involving 983,438 adult cancer survivors to assess cardiovascular risk-prediction models.

Eur Heart JSep 16, 2026Read summary
Clinical ResearchNeurology

Factor XIa Inhibitors for Secondary Prevention After Noncardioembolic Stroke: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of Factor XIa inhibitors in patients with noncardioembolic ischemic stroke or transient ischemic attack (TIA).

NeurologySep 16, 2026Read summary
Case ReportCardiology

Electrocardiographic and Arrhythmic Manifestations of End-Stage Atrial Myopathy in Patients With Longstanding Persistent or Permanent Atrial Fibrillation: A 3-Patient Case Series.

This case series describes three patients with end-stage atrial myopathy and longstanding persistent or permanent atrial fibrillation (AF).

Am J Case RepSep 16, 2026Read case
Clinical ResearchPulmonologyOpen access

ECG-based artificial intelligence for obstructive sleep apnea detection: a mechanism-oriented diagnostic meta-analysis.

This meta-analysis evaluated the diagnostic performance of AI models using ECG signals for detecting obstructive sleep apnea (OSA) across 13 studies.

Sleep BreathSep 16, 2026Read summary
Clinical ResearchCardiologyOpen access

Efficacy and safety of zilebesiran in adults with hypertension: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy and safety of zilebesiran in 1,412 adults with mild to moderate hypertension.

Eur J Clin PharmacolSep 16, 2026Read summary
Clinical ResearchCardiology

Pharmacological lipid-lowering therapies for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia: a systematic review and network meta-analysis.

This systematic review and network meta-analysis aims to evaluate the effects and safety of various lipid-lowering therapies, including statins and non-statin options, for preventing cardiovascular disease in adults…

Cochrane Database Syst RevSep 16, 2026Read summary
Case ReportMedical Genetics

Late Diagnosis of Noonan Syndrome Presenting With Infective Endocarditis: A Multidisciplinary Challenge in an Underserved Population.

A 29-year-old woman from a rural area presented with severe respiratory distress, weight loss, and new cardiac murmurs. Examination revealed dysmorphic features indicative of Noonan syndrome.

Am J Case RepSep 16, 2026Read case
Clinical ResearchCardiology

Endotype-informed therapy and effects on illness perception and psychological health in patients with chest pain and no obstructive coronary artery disease.

The CorCMR trial, a multicenter randomized controlled trial, evaluated the impact of non-invasive stress perfusion cardiovascular magnetic resonance (CMR) on illness perception and psychological health in 250 patients…

Eur Heart J Qual Care Clin OutcomesSep 16, 2026Read summary
Clinical ResearchEndocrinology

Cardiovascular and renal outcomes of GLP-1 receptor agonists in type 2 diabetes mellitus: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on cardiovascular outcomes in 83,004 patients with type 2 diabetes mellitus (T2DM).

Eur Heart J Qual Care Clin OutcomesSep 16, 2026Read summary
Clinical ResearchCardiology

Sodium-glucose cotransporter 2 inhibitors across cardio-reno-metabolic disease and body mass index: a meta-analysis of randomized controlled trials.

This meta-analysis of randomized controlled trials evaluated the impact of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on cardiovascular and all-cause mortality across different body mass index (BMI) categories…

Eur Heart J Qual Care Clin OutcomesSep 16, 2026Read summary

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text

Prefer listening? Personalized audio digests are available with Pro.