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1303 articles

September 202624

Clinical ResearchPsychiatryOpen access

Psychiatric manifestation of neurosarcoidosis: a systematic review with pooled descriptive analysis of case reports and case series.

Neurosarcoidosis is a rare inflammatory disease with a heterogeneous presentation. Psychiatric manifestations may precede neurological involvement, but their prevalence, diagnostic pattern, and treatment outcomes remain…

Rheumatol IntSep 19, 2026Read summary
Clinical ResearchNeurology

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as a cell-free approach in autism spectrum disorder: A systematic review and meta-analysis of preclinical studies.

This systematic review and meta-analysis evaluated the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) in preclinical models of Autism Spectrum Disorder (ASD).

Behav Brain ResSep 19, 2026Read summary
Clinical ResearchPsychiatry

Efficacy and safety of noninvasive brain stimulation for ADHD: a systematic review and meta-analysis of double-blind randomized controlled trials across international English and Chinese databases.

This systematic review and meta-analysis examined double-blind, parallel-group randomised trials of noninvasive brain stimulation (NIBS) for clinical ADHD symptoms, including studies from China.

Psychiatry ResSep 19, 2026Read summary
Clinical ResearchPsychiatry

Anterior cingulate GABA and functional connectivity associated with initial treatment response in first-episode schizophrenia.

This randomized study examined whether anterior cingulate cortex (ACC) GABA levels and functional connectivity were associated with initial antipsychotic response in 87 people with first-episode schizophrenia.

Schizophr ResSep 19, 2026Read summary
Clinical ResearchPsychiatry

Good morning or good evening: Daytime and cortisol as modulators of exposure therapy outcomes.

This double-blind randomized controlled trial examined whether treatment time and endogenous cortisol were associated with outcomes of group exposure therapy in 53 participants with spider-phobia symptoms.

PsychoneuroendocrinologySep 19, 2026Read summary
Clinical ResearchPsychiatry

Distinguishing bipolar disorder from unipolar depression in general practice: A systematic review.

This systematic review examined clinical and historical features that aid in distinguishing bipolar disorder from unipolar depression in general practice.

Eur J Gen PractSep 18, 2026Read summary
Case ReportPsychiatryOpen access

Rechallenge after Clozapine-Induced Neutropenic Events: A Case Series.

This case series discusses 13 patients who were rechallenged with clozapine after experiencing neutropenic events. The majority, 61.5%, were successfully maintained on the medication without fatalities.

Psychopharmacol BullSep 18, 2026Read case
Case ReportPsychiatryOpen access

Olanzapine-Induced Rapid Weight Gain and Metabolic Disorders: A Case Series.

This case series highlights four patients who experienced rapid and significant weight gain while on olanzapine, with three developing new-onset metabolic syndrome.

Psychopharmacol BullSep 18, 2026Read case
Case ReportPsychiatryOpen access

Gabapentin-Induced Severe Vivid Nightmares: A Case Series and Brief Review.

Two patients treated with gabapentin for spinal pain syndromes developed severe vivid nightmares, an underreported psychiatric side effect.

Psychopharmacol BullSep 18, 2026Read case
Clinical ResearchPsychiatryOpen access

Peripheral Inflammatory Biomarkers as Predictors of Antidepressant Treatment Response in Major Depressive Disorder: An Updated Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the role of peripheral inflammatory biomarkers in predicting antidepressant response in adults with major depressive disorder (MDD).

Psychopharmacol BullSep 18, 2026Read summary
Clinical ResearchPsychiatry

Mindfulness-based and mindfulness-informed interventions for internet use disorders in adolescents and young adults: A three-level random-effects meta-analysis.

This systematic review and three-level random-effects meta-analysis assessed mindfulness-based and mindfulness-informed interventions (MBIIs) for internet use disorders in adolescents and young adults.

J Behav AddictSep 18, 2026Read summary
Clinical ResearchPsychiatry

A smartphone-based serious game to improve mental health and medication adherence in adults with depression: A randomised controlled trial.

This randomised controlled trial tested a 9-week digital intervention in 148 adults receiving antidepressants who had residual depressive symptoms.

J Affect DisordSep 18, 2026Read summary
Clinical ResearchPsychiatry

Resilience in the face of risk: A systematic review of neuroimaging studies in individuals at risk for mood disorders.

This systematic review synthesised neuroimaging research on people at elevated risk of mood disorders, including major depressive and bipolar disorders, with particular attention to resilience.

Psychiatry Res NeuroimagingSep 18, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Fine-Tuning, Retrieval-Augmented Generation, and Hybrid Adaptation of Language Models for Clinical Decision-Making in Health Care: Systematic Review.

This systematic review evaluated the effectiveness of fine-tuning, retrieval-augmented generation (RAG), and hybrid adaptation strategies for transformer-based language models in clinical decision-making.

J Med Internet ResSep 17, 2026Read summary
Clinical ResearchPediatricsOpen access

Improving Cardiometabolic Health in Adolescent Girls With Elevated Anxiety: Web-Based Multisite, Pilot, and Feasibility Randomized Controlled Trial.

This pilot randomized controlled trial evaluated the feasibility and acceptability of web-based interpersonal psychotherapy (IPT) and cognitive behavioral therapy (CBT) in adolescent girls aged 12-17 with elevated…

JMIR CardioSep 17, 2026Read summary
Clinical ResearchMedical GeneticsOpen access

Prevalence of neuropsychiatric and seizure disorders in neurofibromatosis type 1: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed the prevalence of neuropsychiatric and seizure disorders in patients with neurofibromatosis type 1 (NF1).

J NeurolSep 17, 2026Read summary
Clinical ResearchPsychiatryOpen access

Mental health burden among survivors of sexual-exploitation trafficking: a global systematic review, meta-analysis, and meta-regression.

This systematic review and meta-analysis examined the mental health burden among survivors of sexual exploitation trafficking, analyzing 18 studies.

Arch Womens Ment HealthSep 17, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of A Virtual Agent-Based Digital Intervention (Echo App V2.0) for Patients With Alcohol Use Disorder: Randomized Controlled Trial.

This randomized controlled trial evaluated the Echo App V2.0, a virtual agent-based digital intervention, in 93 patients with alcohol use disorder (AUD).

J Med Internet ResSep 17, 2026Read summary
Clinical ResearchPsychiatry

Psychosocial interventions for posttraumatic stress disorder in low- and middle-income countries: a Bayesian meta-analysis.

This meta-analysis evaluated the effectiveness of psychosocial interventions for adults with PTSD in low- and middle-income countries (LMICs). It included 55 randomized controlled trials with 5,041 participants.

Psychol MedSep 17, 2026Read summary
Clinical ResearchPsychiatry

Bilateral Transcranial Direct-Current Stimulation Over the Dorsolateral Prefrontal Cortex Significantly Reduces Relief Craving During Alcohol Withdrawal: A Randomized Sham-Controlled Trial Among Inpatients With Alcohol Dependence Syndrome in Northern India.

This randomized controlled trial investigated the effects of bilateral transcranial direct-current stimulation (tDCS) on relief craving in 48 male inpatients with alcohol dependence syndrome during withdrawal.

Prim Care Companion CNS DisordSep 17, 2026Read summary
Clinical ResearchPsychiatry

Psychiatric and medical multimorbidity in anorexia nervosa, bulimia nervosa, and binge-eating disorder: An umbrella review of 61 meta-analyses and 213 meta-analytic associations.

This umbrella review synthesized meta-analyses of observational studies on psychiatric and medical multimorbidity involving anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED).

J Psychosom ResSep 17, 2026Read summary
Clinical ResearchNeurology

Pre-operative neural substrates of deep brain stimulation outcomes: A systematic review and cross-disorder network synthesis.

This systematic review and cross-disorder network synthesis examined whether pre-operative neuroimaging features are associated with deep brain stimulation (DBS) outcomes.

Neurosci Biobehav RevSep 17, 2026Read summary
Clinical ResearchPsychiatry

A systematic review and meta-analysis of the relative and complementary effects of motivational interviewing and cognitive-behavioral treatment for problem gambling and gambling disorder.

This systematic review and meta-analysis compared combined motivational interviewing (MI) and cognitive-behavioral treatment (CBT) with either treatment alone for problem gambling and gambling disorder.

Psychol Addict BehavSep 17, 2026Read summary
Clinical ResearchPsychiatry

Impact of olanzapine on body weight, body mass index, and waist circumference: A time- and dose-response meta-analysis of randomized controlled trials.

This systematic review and meta-analysis pooled randomized controlled trials comparing olanzapine with placebo in adults, assessing body weight, BMI, and waist circumference and examining dose and treatment duration.

Scott Med JSep 17, 2026Read summary

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