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845 articles
September 202624
Isolated clival Langerhans cell histiocytosis in a pediatric patient: systematic review and illustrative case report.
A 3.5-year-old boy presented with isolated clival Langerhans cell histiocytosis, confirmed through histopathological and immunohistochemical evaluation.
FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation: a case report and review of the literature.
A 55-year-old man developed nephrotic syndrome 52 months post-allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia.
Pyogenic Granuloma in the Sinonasal Cavity: A Potential 38-Year Latency Following Foreign Body Entrapment.
A 43-year-old male presented with left-sided nasal obstruction, rhinorrhea, and hyposmia for two months. Endoscopic evaluation and imaging revealed a highly vascular mass on the left middle turbinate.
Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.
A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.
Aspergillus tubingensis pneumonia with pulmonary oxalosis in a virologically suppressed person with HIV: A case report.
A man in his late sixties with virologically suppressed HIV and a CD4 count of 368/μL developed cough, then fever and dyspnea requiring hospitalization. CT showed bilateral pneumonia and a right upper-lobe cavity.
Isolated Cervical Lymph Node Kimura Disease in a Child Mimicking Tuberculosis: A Diagnostic Challenge.
A 16-year-old boy presented with a progressive, painless left cervical nodular swelling, preceded by low-grade fever. Examination found cervical and axillary lymphadenopathy and icterus, without visceromegaly.
Flow Cytometry-Guided Diagnosis of Cortical T-Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement.
A 57-year-old man presented with dyspnea, a large mediastinal mass causing superior vena cava syndrome, and pleural and pericardial effusions. Cytology and biopsy showed a diffuse blastoid lymphoid infiltrate.
Unveiling the Prognostic Power of Circulating Tumor DNA in Multiple Myeloma: A Systematic Review and Updated Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic significance of circulating tumor DNA (ctDNA) in 948 patients with multiple myeloma (MM).
Lumbar spinal brucellosis presenting as an atypical epidural abscess.
A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.
Scleromyxedema-Associated Myopathy and Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS) as manifestations of Monoclonal Gammopathy of Clinical Significance (MGCS): a disease spectrum between autophagy dysfunction and inflammation.
This report discusses two patients with Scleromyxedema-Associated Myopathy (SAM) and one with Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS), both associated with Monoclonal Gammopathy of Clinical…
Genomic evidence implicates patient-room showers in Mycobacterium llatzerense bacteremia among two cord blood transplant recipients.
Two cord blood transplant recipients developed persistent fever despite broad-spectrum therapy, with blood cultures eventually growing acid-fast bacilli. Sequencing identified Mycobacterium llatzerense.
Peritoneal dialysis-associated peritonitis caused by Brevundimonasaurantiaca.
A 55-year-old man with end-stage kidney disease receiving continuous ambulatory peritoneal dialysis developed peritonitis, with Brevundimonas aurantiaca recovered from two consecutive effluent cultures.
Exploration of tumor genomics associated with prolonged benefit from or resistance to talazoparib monotherapy in patients with metastatic castration-resistant prostate cancer.
This phase II trial analysis explored tumor genomic features associated with duration of benefit from talazoparib monotherapy in pretreated patients with metastatic castration-resistant prostate cancer and HRR gene…
Primary adrenal lymphoma presenting as primary adrenal insufficiency.
A man in his late 60s presented with symptoms of adrenal failure, including anaemia and hypercalcaemia. Initial tests indicated adrenal insufficiency, and imaging showed bilateral adrenal enlargement.
Metastatic dedifferentiated malignant melanoma with spindle cell morphology.
A man in his early 60s presented with a slow-growing skin lesion on his back, which had been present for two decades, and a newly noticed right axillary mass.
Crohn's disease unmasks pulmonary sarcoidosis on biologic screening: dual granulomatous pathology responsive to infliximab.
A man in his 30s with a history of ileal Crohn's disease was diagnosed with pulmonary sarcoidosis during routine pre-biologic screening, despite being asymptomatic.
Localised cutaneous leishmaniasis in an immunosuppressed host: the role for adjuvant photodynamic therapy after incomplete amphotericin B response.
An immunocompromised man in his 70s presented with a 15-year verrucous plaque on the right hallux, initially misdiagnosed as squamous cell carcinoma.
Cutaneous T-cell lymphoma emerging during long-term dupilumab therapy in a patient with longstanding atopic diathesis: diagnostic challenges and mechanistic considerations.
A woman in her 40s with a long history of atopic dermatitis developed patch-stage mycosis fungoides after over 5 years of stable dupilumab therapy.
Primary renal glomus tumours of uncertain malignant potential: diagnostic challenges and insights from two instances.
Two elderly patients presented with abdominal pain and were found to have large renal masses on imaging. Both underwent nephrectomy, and histopathological analysis revealed glomus tumors with atypical features but not…
Circulating tumour DNA and its clinical relevance in predicting progression-free survival and overall survival in patients with advanced breast cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic value of circulating tumour DNA (ctDNA) in predicting progression-free survival (PFS) and overall survival (OS) in patients with advanced breast cancer…
Ventral Cervical Spinal Schwannoma Presenting as Progressive Myelopathy.
A male in his 20s presented with a two-year history of progressive paraparesis and urinary incontinence. Neurological examination revealed signs of spasticity and reduced lower-limb power.
Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.
A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…
Mucinous Adenocarcinoma Arising in a Mature Ovarian Teratoma.
A woman in her 30s presented with a 19 cm right ovarian mass. She underwent extensive surgical intervention, including right salpingo-oophorectomy and lymphadenectomy.
Phlegmonous Gastritis Refractory to Antibiotics with Subsequent Improvement on Empiric Quadruple Therapy.
A 59-year-old woman presented with two days of severe nausea, vomiting, and inability to tolerate oral intake while on chronic proton-pump inhibitor therapy.
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