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1303 articles
September 202624
A workbook- and audio-administered, telephone-guided, low-intensity cognitive behavioural therapy intervention (EJDeR) for parents of persons treated for cancer during childhood: protocol for the CHANGE-pilot randomised controlled trial.
The CHANGE-pilot trial is a parallel-group, two-arm, pilot randomized controlled trial assessing the feasibility of the EJDeR intervention, a low-intensity cognitive behavioural therapy for parents of children treated…
Impulsivity, Compulsivity, Social Inappropriateness, and Other Neuropsychiatric Features in Cerebellar Histiocytosis.
This report describes six patients with multisystem Langerhans cell histiocytosis (LCH) who exhibited neurological and psychiatric disturbances linked to cerebellar lesions.
Work-focused cognitive behavioural therapy for common mental disorders: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of work-focused cognitive behavioural therapy (W-CBT) for common mental disorders (CMDs) in working-age adults.
Rapid Review of the Brief Observation of Social Communication Change (BOSCC) Shows It Can Detect Behavioural Changes in Social Communication in Autism.
This rapid review evaluated the Brief Observation of Social Communication Change (BOSCC) in detecting behavioral changes in social communication among autistic children.
Low-dose versus standard-dose antipsychotic treatment in first-episode schizophrenia: A secondary analysis of EUFEST data.
This secondary analysis of the open-label randomized EUFEST trial compared outcomes by dose group among 421 participants with first-episode schizophrenia.
Task-based metacognition and insight in schizophrenia spectrum disorders: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether performance on behavioral metacognitive tasks is associated with insight in adults with schizophrenia spectrum or other psychosis spectrum disorders.
Patterns, predictors and outcomes of the joint trajectories of positive and negative symptoms in patients with early psychosis: 12-year follow-up of the randomized controlled trial on extended early intervention.
This 12-year follow-up of a randomized controlled trial of extended early intervention examined joint positive and negative symptom trajectories in people with first-episode psychosis.
Loneliness in migrants: Are there differences compared to non-migrants? A systematic review and meta-analysis.
This systematic review and meta-analysis examined loneliness in migrants compared with non-migrants, drawing on quantitative studies identified through searches of four databases.
A Brief emotion-focused psychodynamic intervention for fatigue, pain, and health-related quality of life in women with relapsing-remitting multiple sclerosis: A randomized pilot trial.
This randomized pilot trial assessed the feasibility and preliminary clinical outcomes of an eight-session individual emotion-focused psychodynamic intervention in 30 women with relapsing-remitting multiple sclerosis…
PTSD treatment impacts on pain: secondary analysis of sertraline, prolonged exposure, and their combination.
This randomized controlled trial analyzed the effects of PTSD treatments on pain in 196 veterans. It found that all treatment groups, including Prolonged Exposure plus placebo, Prolonged Exposure plus Sertraline, and…
Effectiveness of Telehealth Care Interventions for Women's Mental Health During and After the COVID-19 Pandemic: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of telehealth interventions for improving mental health outcomes in women during and after the COVID-19 pandemic.
Supporting the Primary Outcomes of the Mirai Trial for the Adjunctive Digital Therapeutic Rejoyn (CT-152) in the Treatment of Major Depressive Disorder: Meaningful Change Analysis in the Montgomery-Åsberg Depression Rating Scale.
This randomized controlled trial analyzed the adjunctive digital therapeutic Rejoyn (CT-152) for major depressive disorder, focusing on the Montgomery-Åsberg Depression Rating Scale (MADRS).
An Open-Label, Dose-Escalation Trial of Psilocybin-Assisted Therapy for Bipolar II Depression.
This open-label, single-arm pilot trial evaluated the safety, tolerability, and preliminary efficacy of psilocybin therapy in 14 individuals with bipolar II disorder (BD-II) and depression.
How should we teach psychiatric formulation? A systematic review of the evidence.
This systematic review examined the literature on teaching psychiatric formulation, identifying gaps and inconsistencies in educational strategies and outcomes.
Effect of modernized collaborative care for depression on individual depressive symptoms: A secondary analysis of the eIMPACT trial.
This secondary analysis of the eIMPACT trial evaluated the effects of modernized collaborative care on individual depressive symptoms in 216 primary care patients.
Comparing lithium and valproate in reducing suicide risk: A territory-wide retrospective cohort study with pairwise and network meta-analysis.
This study evaluated the effectiveness of lithium versus valproate in reducing suicide risk among patients with bipolar disorder using a retrospective cohort design.
Adjunctive psychobiotic Lactiplantibacillus plantarum PS128 ameliorates gastrointestinal comorbidities and alters circulating miRNAs and gut microbiota in children with Tourette syndrome: a randomized controlled trial.
This randomized controlled trial evaluated the effects of the psychobiotic Lactiplantibacillus plantarum PS128 on children aged 4-18 with Tourette syndrome.
Feasibility and acceptability of the Unified Protocol for anxiety and depression in Pakistan: a pilot randomized controlled trial.
This pilot randomized controlled trial assessed the feasibility and acceptability of the Urdu Adapted Unified Protocol (UA-UP) for anxiety and depression in 51 adults in Pakistan.
A systematic review of clinical practice guidelines for suicide and self-harm prevention in adults.
This systematic review evaluated clinical practice guidelines for assessing, managing and treating adults who self-harm, with or without suicidal intent.
Anxiety disorders, PTSD, and risk of first-ever stroke: A meta-analysis of 11 million participants.
This meta-analysis pooled 23 longitudinal cohort studies involving 11,181,338 participants to assess whether anxiety disorders, obsessive-compulsive disorder (OCD), and PTSD were associated with first-ever stroke.
Heartbeat counting task performance in alcohol use disorder: a systematic review and meta-analysis.
This systematic review and meta-analysis examined heartbeat counting task (HCT) performance in adults with alcohol use disorder (AUD) compared to healthy controls (HC).
Subjective and objective memory effects after electroconvulsive therapy for depressive disorders - systematic review and meta-analysis.
This systematic review and meta-analysis examined changes in objective and subjective memory after electroconvulsive therapy (ECT) for major depressive episodes.
Measuring impulsivity differently yields different answers: A three-level meta-analysis of associations between impulsivity and adolescent non-suicidal self-injury.
This three-level random-effects meta-analysis examined associations between impulsivity and non-suicidal self-injury (NSSI) in adolescents, synthesising 37 studies (N = 69,572).
Haloperidol for Hypoactive and Hyperactive Delirium in ICU Patients-A Post Hoc Bayesian Analysis of the AID-ICU Trial.
This post hoc analysis of the AID-ICU trial evaluated the effects of haloperidol on delirium subtypes in 987 ICU patients. Haloperidol was linked to more days alive out of hospital, with a 76.5% probability of greater…
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