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1320 articles
October 202624
Chronic posthypoxic myoclonus: Lance-Adams syndrome.
A man in his 20s developed chronic intentional myoclonus following two cardiac arrests, leading to persistent generalized myoclonic seizures.
A Systematic Review of Stem Cell Secretome-Derived Exosomes for Neuropathic Pain: Therapeutic Mechanisms and Translational Potential.
This systematic review assessed the therapeutic mechanisms and potential of stem cell secretome-derived exosomes for neuropathic pain (NP) in preclinical and clinical studies.
TRICALS risk score augments but cannot replace neurofilament as a prognostic biomarker in ALS.
This randomized controlled trial evaluated the TRICALS risk score as a prognostic tool in amyotrophic lateral sclerosis (ALS) using data from the MIROCALS trial (n = 220).
Associations between duration of status epilepticus and clinical outcomes in adults: a systematic review.
This systematic review examined the relationship between the duration of status epilepticus (SE) and clinical outcomes in adults, analyzing 43 studies.
Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
This individual participant data meta-analysis examined amyloid PET scans from 49,227 participants across 53 studies to establish Centiloid positivity cutoffs for Alzheimer disease diagnosis.
Standardized Acupuncture Plus Modified Xiaoxuming Decoction for Acute Ischemic Stroke: A Randomized Controlled Trial.
This single-center, assessor-blinded randomized controlled trial enrolled adults with imaging-confirmed acute ischemic stroke within 72 hours and compared standard care with or without standardized acupuncture plus…
Bilateral gamma knife radiosurgery in severe essential tremor: a prospective trial.
This phase II prospective trial evaluated the safety and efficacy of staged bilateral Gamma Knife radiosurgery (GKS) of the ventral intermedius thalamic nucleus in 33 patients with severe essential tremor.
Machine Learning and Deep Learning for the Diagnosis of Cervical Degenerative Diseases: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated traditional machine learning (TML) and deep learning (DL) approaches for diagnosing cervical degenerative diseases, analyzing data from 30 studies involving 25,301…
Electroacupuncture Targeting the NLRP3 Inflammasome in Senescence‑associated Cognitive Impairment: Mechanistic Synthesis and Meta‑analysis of Clinical Randomized Controlled Trials.
This meta-analysis reviewed nine randomized controlled trials involving 614 participants to evaluate the effects of electroacupuncture on senescence-associated cognitive impairment (SACI).
Familial hypomagnesemia with secondary hypocalcemia: a novel TRPM6 mutation associated with treatment-resistant migraine in a North African family.
An 18-year-old woman from a consanguineous Moroccan family presented with lifelong hypomagnesemia and a severe migraine attack accompanied by paresthesias and muscle cramps.
Systemic inflammatory response syndrome and adverse outcomes in acute intracerebral hemorrhage: a meta-analysis.
This meta-analysis evaluated the prognostic significance of systemic inflammatory response syndrome (SIRS) in 6,976 patients with acute intracerebral hemorrhage (ICH).
Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.
This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.
The utility of magnetic resonance imaging of the spinal cord in paediatric transverse myelitis: A systematic review.
This systematic review assessed spinal cord MRI findings, agreement with CSF inflammation, and prognostic associations in children with monophasic acute transverse myelitis.
Frontal aperiodic activity and sensorimotor theta clustering are differentially modulated by tDCS during proprioceptive training in Parkinson's disease: An EEG study.
This randomized controlled EEG study examined whether anodal transcranial direct current stimulation (tDCS) over the supplementary motor area altered neural measures during proprioceptive training in 24 people with…
The role of PRKRA mutation in antipsychotic-induced extrapyramidal symptoms: a case report and implications for precision psychiatry.
A 43-year-old woman with atypical psychosis developed severe extrapyramidal symptoms after treatment with olanzapine, an antipsychotic described as having a lower propensity for these effects.
Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral near-infrared spectroscopy (cNIRS), and targeted neonatal echocardiography…
The Therapeutic Potential of MicroRNAs Delivered By Mesenchymal Stem Cells in Parkinson's Disease, Alzheimer's Disease, and Stroke: A Systematic Review of Preclinical Studies.
This systematic review evaluated 37 preclinical studies on the therapeutic potential of mesenchymal stem cells (MSCs) and their derived microRNAs (miRNAs) in Parkinson's disease, Alzheimer's disease, and stroke.
Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Cognitive Outcome after Stroke: A Systematic Review.
This systematic review examined the association between the BDNF Val66Met polymorphism and cognitive outcomes in 2,494 adults post-stroke.
HD-tACS at 40 Hz improves consciousness and brain connectivity in prolonged disorders of consciousness: a randomized sham-controlled clinical trial.
This randomized, sham-controlled clinical trial evaluated 40 Hz and 4 Hz high-definition transcranial alternating current stimulation (HD-tACS) in 60 patients with prolonged disorders of consciousness.
Excellent response to high-dose Riboflavin in Brown-Vialetto-Van Laere syndrome: A case report.
A young Asian man presented with progressive bilateral hearing loss, dysphagia, limb weakness, and respiratory issues. Neurological examination revealed significant deficits, and genetic testing confirmed pathogenic…
Long-term integrative personalized medicine care in massive brainstem hemorrhage: A CARE-compliant case report.
A 48-year-old female presented with a massive pontine hemorrhage, resulting in significant functional impairment and recurrent infections.
The effect of intermittent theta burst stimulation on central poststroke pain: A pilot randomized controlled trial.
This pilot randomized controlled trial investigated the effects of intermittent theta burst stimulation (iTBS) on central poststroke pain (CPSP) in 20 patients.
Prevalence of metabolic syndrome among patients with Alzheimer disease: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of metabolic syndrome (MetS) in patients with Alzheimer disease (AD).
Impact of acupuncture on lower limb motor function recovery after stroke: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of acupuncture on lower limb motor function recovery after stroke, including six randomized controlled trials.
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