Trending archive
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845 articles
October 202624
The impact of intratumor heterogeneity on outcome and resistance to therapy in primary breast cancer: a systematic review.
This systematic review examines the impact of intratumor heterogeneity (ITH) on chemotherapy resistance in primary breast cancer, analyzing 12 studies across various tumor subtypes.
Trial-specific absolute disease-free survival effects of postoperative PD-1/PD-L1 blockade after complete resection of NSCLC: A systematic review.
This systematic review estimated absolute disease-free survival (DFS) effects of postoperative single-agent PD-1/PD-L1 blockade after complete resection of non-small-cell lung cancer.
Primary pulmonary mucosa-associated lymphoid tissue lymphoma presenting as a right hilar mass: A case report.
A 44-year-old male presented with an incidental right hilar mass discovered during routine screening. He was asymptomatic, and imaging revealed a 3.9 × 3.5 cm mass causing bronchial compression and post-obstructive…
Cholecystogastric fistula masquerading as gastrointestinal stromal tumour: Unusual presentation of gallbladder adenomyomatosis - a case report.
A 71-year-old woman presented with acute abdominal pain and signs of mechanical small-bowel obstruction. Imaging revealed a 6-cm mass near the gastric antrum, initially suspected to be an invasive gastrointestinal…
Pulmonary cryptococcosis mimicking metastatic progression despite systemic disease stability in advanced colon cancer: A case report and literature review.
A patient with advanced colon cancer undergoing chemotherapy presented with new pulmonary nodules on imaging, despite stable systemic disease and declining tumor markers.
Angioimmunoblastic T-cell lymphoma with secondary hemophagocytic lymphohistiocytosis initially misdiagnosed as classical Hodgkin lymphoma: A case report.
A 72-year-old man presented with fatigue, recurrent fever, severe pancytopenia, and splenomegaly, initially diagnosed with Hodgkin lymphoma.
Recurrent giant retroperitoneal liposarcoma: A case report.
A 48-year-old male with a 13-year history of recurrent myxoid liposarcoma presented with significant abdominal distension due to a massive abdominopelvic mass measuring 352 mm.
Concurrent presentation of distinct extranodal and splenic marginal zone lymphomas.
A patient was diagnosed with both extranodal marginal zone lymphoma (EMZL) of the ocular adnexa and splenic marginal zone lymphoma (SMZL).
A Rare Case of Nodular Fasciitis of the Hard Palate with Complete Clinical Resolution.
A 24-year-old female presented with a rapidly enlarging, pedunculated mass on the hard palate, initially diagnosed as a pyogenic granuloma.
Tumor-Free Circulating Tumor DNA in Node-Negative Rectal Cancers Undergoing Neoadjuvant Chemotherapy, Excision, and Observation in the Phase II NEO Trial (CO.28).
The Phase II NEO trial investigated the role of circulating tumor DNA (ctDNA) in guiding treatment decisions for 53 patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy and transanal excision.
Amyloid Neuropathies.
This article reviews the pathophysiology, epidemiology, and clinical features of amyloid neuropathies, with a focus on light chain (AL) amyloidosis and hereditary amyloidogenic transthyretin (ATTRv) amyloidosis, and…
Comparison of Molecular Methods With Culture for Identifying Microbial Etiology in Pediatric Empyema Thoracis: A Systematic Review of Diagnostic Test Accuracy.
This systematic review evaluated the diagnostic accuracy of molecular methods versus culture for identifying microbial etiology in pediatric empyema thoracis.
Primary Surgical Resection of Localized Cervical Kaposiform Hemangioendothelioma in a Neonate: A Potentially Curative Strategy in Selected Patients.
A term female neonate had a 4 × 4 cm cervical mass at birth. Imaging showed a well-circumscribed, highly vascular lesion without infiltration or compression of vital structures; no coagulopathy was detected.
Alpha-catenin Mutation-associated Synchronous Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma With Numerous Adenomatoid Nodules.
A 59-year-old woman with a history of breast cancer was found to have a thyroid nodule during a chest CT. Subsequent biopsies revealed synchronous minimally invasive follicular thyroid carcinoma and classic papillary…
Well-differentiated SMARCB1-deficient Pancreatic Malignancy With Indolent Liver Metastases.
A 66-year-old woman underwent distal pancreatectomy for a pancreatic tail malignancy, later developing liver metastases six years post-surgery.
Primary malignant mesothelioma of the tunica vaginalis presenting as hydrocele: imaging pitfalls.
A man in his late 70s presented with a progressive, painless scrotal swelling initially diagnosed as a simple hydrocele via ultrasound.
Paraneoplastic dermatomyositis preceding detection of metastatic oesophageal squamous cell carcinoma after prolonged remission following pembrolizumab therapy.
A man in his late fifties with a history of treated oesophageal squamous cell carcinoma developed severe dermatomyositis after six years of remission.
Malignant phyllodes tumour with spinal metastasis presenting as cauda equina syndrome.
A female in her early 50s with a history of borderline phyllodes tumour underwent right mastectomy and adjuvant radiotherapy.
Gastric neuroendocrine tumours after prolonged proton pump inhibitor use.
A woman in her 40s with chronic gastro-oesophageal reflux disease had been on proton pump inhibitors for 20 years. She was diagnosed with gastric neuroendocrine tumours during an upper endoscopy.
Primary tongue leiomyosarcoma.
A male patient in his mid 50s presented with a non-healing ulcer on the right lateral border of the tongue, accompanied by impaired tongue movement.
Resistant Hypertension Secondary to Renal Arteriovenous Malformation: A Case of Cure After Nephrectomy.
A 33-year-old woman with longstanding uncontrolled hypertension requiring five antihypertensive agents was evaluated for refractory blood pressure control.
New Primary and Secondary Prevention Measures for Cutaneous Melanoma: A Systematic Review.
This systematic review evaluated recent evidence on primary and secondary prevention strategies for cutaneous melanoma, analyzing 24 studies.
Molecular Profiling of Tisotumab Vedotin-Treated Patients Identifies Immune Pathways Associated with Clinical Activity.
This phase II multicenter trial evaluated the efficacy of tisotumab vedotin (TV) in patients with recurrent or metastatic cervical cancer (r/mCC).
Tumor-Infiltrating Lymphocytes as a Predictor of Adjuvant Avelumab Efficacy in Patients with High-risk Triple-Negative Breast Cancer.
This phase III randomized controlled trial investigated the prognostic and predictive value of tumor-infiltrating lymphocytes (TIL) in 466 patients with high-risk early triple-negative breast cancer (TNBC) receiving…
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