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1320 articles

October 202624

Case ReportMedical Genetics

Two siblings presented with spastic paraplegia and psychomotor retardation with or without seizures with HACE1 variants: A case report and literature review.

Two siblings from a nonconsanguineous Chinese family had infantile-onset hypotonia, global developmental and motor delay, gait impairment, language delay, and dysarthria; the older sister also had recurrent febrile…

Medicine (Baltimore)Oct 9, 2026Read case
Clinical ResearchPhysical Medicine & Rehabilitation

Efficacy of Kinesio tape for central facial paralysis: A prospective, randomized sham-controlled, single-blinded clinical trial.

This prospective, randomized, single-blind, sham-controlled trial evaluated Kinesio tape (KT) as an adjunct to routine rehabilitation in 121 adults after a first stroke with central facial paralysis.

Medicine (Baltimore)Oct 9, 2026Read summary
Clinical ResearchNeurology

Low-Frequency Repetitive Transcranial Magnetic Stimulation with Sensory Arousal Nursing for Post-Stroke Dysphagia.

This single-center, randomized, assessor-blinded study evaluated low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with sensory arousal nursing versus routine nursing in 160 patients with acute…

J Vis ExpOct 9, 2026Read summary
Clinical ResearchNeurology

Stakeholder Perspectives on Digital Health Technologies in Poststroke Self-Management and Rehabilitation: Systematic Review Based on the NASSS Framework.

This systematic review synthesized stakeholder perspectives on digital health technologies (DHTs) for poststroke self-management and rehabilitation, mapping findings to the NASSS framework.

JMIR Mhealth UhealthOct 9, 2026Read summary
Case ReportRadiology (Diagnostic)

I saw the "molar tooth" sign: A bite into Joubert syndrome.

The report describes recognition of the molar tooth sign on MRI in a patient with Joubert syndrome, a congenital hindbrain malformation.

Clin ImagingOct 9, 2026Read case
Clinical ResearchNeurology

Effects of Blood Pressure Lowering by Hematoma Location in Acute Intracerebral Hemorrhage.

This pooled individual-patient analysis of five international randomised controlled trials examined whether hematoma location modifies the effect of early intensive blood pressure lowering in acute intracerebral…

NeurologyOct 8, 2026Read summary
Clinical ResearchNeurology

Astrocytic and Axonal Injury Biomarkers in AQP4 Antibody-Positive NMOSD: Insights From PREVENT and CHAMPION-NMOSD.

This biomarker analysis used samples from the phase 3 PREVENT and CHAMPION-NMOSD trials to assess serum GFAP and NfL in people with AQP4 antibody-positive NMOSD receiving eculizumab or ravulizumab.

Neurol Neuroimmunol NeuroinflammOct 8, 2026Read summary
Clinical ResearchCardiologyOpen access

Efficacy and safety of PCSK9 inhibitors combined with statins in acute ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis of randomized controlled trials compared PCSK9 inhibitors plus statins with statins alone in patients with acute ischemic stroke.

J NeurolOct 8, 2026Read summary
Clinical ResearchNeurologyOpen access

Multimodal MRI markers of white matter hyperintensities and their impact on cognition in cerebral small vessel disease: a systematic review.

This systematic review examined associations between multimodal MRI markers of white matter hyperintensities (WMH) and cognition in adults with cerebral small vessel disease.

Brain Imaging BehavOct 8, 2026Read summary
Case ReportMedical GeneticsOpen access

Contrasting clinical trajectories in two ALS patients with rare FUS variants: implications for variant interpretation, penetrance, and trial readiness.

The report describes two patients with amyotrophic lateral sclerosis (ALS) carrying rare FUS variants. Their clinical courses differed, despite the association of FUS-related ALS with relatively aggressive disease.

NeurogeneticsOct 8, 2026Read case
Case ReportOphthalmologyOpen access

Trigeminal sensory neuropathy developing as a late complication after the treatment of surgically induced necrotizing scleritis following pterygium surgery: a case report and literature review.

A 31-year-old woman developed right-eye irritation, reduced vision, and photophobia after bilateral pterygium surgery. Examination showed melting of the conjunctival autograft with exposed sclera and a visible choroidal…

BMC OphthalmolOct 8, 2026Read case
Case ReportInfectious DiseasesOpen access

Varicella zoster virus meningitis with a dermatomal rash in immunocompetent hosts: a systematic review and novel case report.

A 44-year-old immunocompetent man presented with fever, severe headache, and a right-sided vesicular rash in the C4-C5 dermatomes. He was initially misdiagnosed with a tick-borne illness.

J NeurovirolOct 8, 2026Read case
Clinical ResearchNeurologyOpen access

Clinical and Electrophysiological Heterogeneity of Orthostatic Tremor: An Individual Patient Data Analysis.

Orthostatic tremor (OT) is traditionally classified using tremor frequency and the presence of associated neurological signs.

Tremor Other Hyperkinet Mov (N Y)Oct 8, 2026Read summary
Case ReportNeurologyOpen access

Bobble-Head Doll Syndrome Caused by Aqueductal Web-Associated Obstructive Hydrocephalus in an Adult: A Case Report with Video.

A 24-year-old man developed progressive memory impairment, gait instability, urinary incontinence, and an irregular side-to-side (“no-no”) head tremor that improved with a sensory trick.

Tremor Other Hyperkinet Mov (N Y)Oct 8, 2026Read case
Clinical ResearchNeurology

Intracerebral stimulation inducing emotions in SEEG: a systematic review.

This systematic review examined subjective emotional responses to direct intracerebral stimulation during SEEG, synthesizing 34 publications (21 cohort studies and 13 clinical cases) involving 2434 patients and 14,492…

NeuroimageOct 8, 2026Read summary
Case ReportOncology (Medical)

Atypical presentations of Lhermitte's sign after treatment for human papillomavirus-associated oropharyngeal squamous cell carcinoma.

Two patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma developed Lhermitte’s sign after chemoradiotherapy.

BMJ Case RepOct 7, 2026Read case
Case ReportNeurology

Fregoli syndrome in an adolescent with Moyamoya disease.

An early adolescent with known Moyamoya disease developed acute psychosis after a febrile illness accompanied by headache and vomiting.

BMJ Case RepOct 7, 2026Read case
Case ReportNeurology

Staged bilateral MR-guided focused ultrasound thalamotomy in a patient with cerebral cavernous malformations.

A man in his late 60s with medication-refractory essential tremor was found on preoperative MRI to have cavernous malformations in the left caudate head and basal ganglia, with an associated developmental venous anomaly…

BMJ Case RepOct 7, 2026Read case
Clinical ResearchAnesthesiology

Effects of remimazolam versus propofol on cerebral oxygenation in elderly patients undergoing prone spine surgery: study protocol for a randomised controlled trial.

This article describes the protocol for a prospective, single-centre randomised controlled trial comparing remimazolam with propofol-based total intravenous anaesthesia in elderly patients undergoing elective thoracic…

BMJ OpenOct 7, 2026Read summary
Case ReportNeurologyOpen access

Parkinsonism with Reduced Striatal Uptake on DAT-SPECT in a Patient Harboring a Novel KCND3 Variant.

A Japanese patient with a novel KCND3 missense variant classified as a variant of uncertain significance had childhood-onset, slowly progressive cerebellar ataxia and asymmetric parkinsonism, a phenotype compatible with…

CerebellumOct 7, 2026Read case
Clinical ResearchNeurologyOpen access

Healthcare costs and burden of myasthenia gravis for patients and society: a systematic review.

This systematic review examined healthcare and societal costs associated with myasthenia gravis (MG), including 44 studies selected from 1,374 records.

J NeurolOct 7, 2026Read summary
Case ReportNeurologyOpen access

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.

A 52-year-old woman presented with positional vertigo and was initially diagnosed with right superior semicircular canal benign paroxysmal positional vertigo (BPPV).

J Med Case RepOct 7, 2026Read case
Case ReportNeurologyOpen access

Multiple Sclerosis During Pregnancy and the Postpartum Period: Diagnostic and Multidisciplinary Challenges in Two Cases.

The report describes two pregnant women with progressive focal neurological symptoms and brain MRI abnormalities concerning for central nervous system demyelination.

Int Med Case Rep JOct 7, 2026Read case
Clinical ResearchNeurology

Challenging historical associations and reassuring women: an updated meta-analysis of multiple sclerosis relapse risk following assisted reproductive technology.

This systematic review and random-effects meta-analysis examined whether assisted reproductive technology (ART) is associated with multiple sclerosis (MS) relapses in women with MS or incident MS in previously healthy…

Mult Scler Relat DisordOct 7, 2026Read summary

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