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1003 articles
September 202624
Saprochaete pneumonia presenting as septic shock in an elderly patient with poorly controlled diabetes mellitus.
An elderly woman with poorly controlled diabetes presented with community-acquired pneumonia, septic shock, and multi-organ dysfunction. Despite initial antibiotic treatment, her condition deteriorated.
Effectiveness of psychosocial counselling on treatment adherence among patients with a new tuberculosis diagnosis in primary care: a study protocol for a cluster-randomised controlled trial.
This study protocol outlines a cluster-randomised controlled trial aimed at evaluating the effectiveness of psychosocial counselling on treatment adherence among newly diagnosed tuberculosis patients in primary care…
Positive Syphilis Serology With Concurrent Disseminated Talaromycosis marneffei in a Patient With HIV: A Case Report.
A 37-year-old male with HIV presented with a rash and was initially diagnosed with secondary syphilis based on positive serology. After ampicillin treatment failed to improve his condition, he developed fever and cough.
Urinary dipstick findings and UTI risk with SGLT2 inhibitors: a post-hoc analysis of the CANVAS and CREDENCE trials.
This post-hoc analysis of the CANVAS and CREDENCE trials evaluated the relationship between urinary dipstick findings and UTI risk in 8614 participants with type 2 diabetes.
Severe upper limb soft tissue infection with compartment syndrome following a scratch injury: a case report.
A 58-year-old female teacher developed a severe soft tissue infection in her left arm following a minor scratch from a student.
A community-based participatory research and community health workers-led health education strategy for schistosomiasis control among schoolchildren in Pemba Island, Zanzibar: a cluster-randomized trial.
This cluster-randomized controlled trial evaluated a community-based participatory research (CBPR) approach led by community health workers for schistosomiasis control among schoolchildren in Pemba, Zanzibar.
8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.
The RESOLVE multicentre, open-label, randomised non-inferiority trial compared 8 versus 12 weeks of daily sofosbuvir-velpatasvir in treatment-naive adults with chronic hepatitis C without cirrhosis at five publicly…
BK Virus-Associated Hemorrhagic Cystitis in Nontransplanted Children With Hematological Malignancies: A Single-Center Case Series.
A single-center retrospective series identified six nontransplanted children with leukemia or lymphoma who developed BK virus-associated hemorrhagic cystitis during a 17-year period.
Aspergillus tubingensis pneumonia with pulmonary oxalosis in a virologically suppressed person with HIV: A case report.
A man in his late sixties with virologically suppressed HIV and a CD4 count of 368/μL developed cough, then fever and dyspnea requiring hospitalization. CT showed bilateral pneumonia and a right upper-lobe cavity.
Lumbar spinal brucellosis presenting as an atypical epidural abscess.
A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.
Exploring the relationship between HIV Testing frequency and sexual behavior, prevention prophylaxis use among MSM in Southern China.
This randomized controlled trial investigated the relationship between HIV testing frequency, sexual behaviors, and prophylaxis use among 327 men who have sex with men (MSM) in Guangxi, China.
Real-world evaluation of 2023-2024 XBB.1.5 mRNA and protein-based COVID-19 vaccine reactogenicity from the randomized BEEHIVE trial.
This randomized controlled trial evaluated the reactogenicity of the 2023-2024 XBB.1.5 mRNA and protein-based COVID-19 vaccines in participants with prior mRNA vaccination.
Genomic evidence implicates patient-room showers in Mycobacterium llatzerense bacteremia among two cord blood transplant recipients.
Two cord blood transplant recipients developed persistent fever despite broad-spectrum therapy, with blood cultures eventually growing acid-fast bacilli. Sequencing identified Mycobacterium llatzerense.
Peritoneal dialysis-associated peritonitis caused by Brevundimonasaurantiaca.
A 55-year-old man with end-stage kidney disease receiving continuous ambulatory peritoneal dialysis developed peritonitis, with Brevundimonas aurantiaca recovered from two consecutive effluent cultures.
A Phase I, randomized, double-blind, placebo-controlled, dose escalation study to evaluate the safety, tolerability, and pharmacokinetics of intravenous ertapenem and zidebactam in combination (WCK 6777) in healthy adult subjects.
This first-in-human, randomized, double-blind, placebo-controlled Phase I dose-escalation study assessed safety, tolerability, and pharmacokinetics of intravenous ertapenem plus zidebactam (WCK 6777) in healthy adults…
Localised cutaneous leishmaniasis in an immunosuppressed host: the role for adjuvant photodynamic therapy after incomplete amphotericin B response.
An immunocompromised man in his 70s presented with a 15-year verrucous plaque on the right hallux, initially misdiagnosed as squamous cell carcinoma.
Delayed cardiac conduction disease in a young adult following childhood Chagas infection.
A Bolivian man in his 30s presented to the emergency department with non-exertional chest pain and intermittent second-degree atrioventricular block.
Diagnostic Challenges in mNGS for Pulmonary Mucormycosis Presenting with Imaging Features Resembling Those of Lung Cancer.
A 67-year-old woman with diabetes presented with cough and sputum production. Imaging suggested lung cancer due to a right hilar mass, bronchial obstruction, and mediastinal lymphadenopathy.
Campylobacter ureolyticus-associated Fournier's gangrene following anal fissure infection in a patient with diabetes and immunosuppression.
A 75-year-old man with type 2 diabetes receiving long-term corticosteroids presented with progressive scrotal pain and left thigh swelling.
Pharmacokinetics, safety, and tolerability of ceftibuten-ledaborbactam etzadroxil in participants with renal impairment.
This phase 1 clinical trial assessed single-dose pharmacokinetics and safety of ceftibuten-ledaborbactam etzadroxil in 32 participants across normal renal function, varying degrees of renal impairment, and end-stage…
Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.
A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…
Impact of resolved hepatitis B virus infection on clinical outcomes in patients with diffuse large B-cell lymphoma: a supplementary analysis of JCOG0601.
This supplementary analysis of the randomized JCOG0601 phase II/III trial examined whether resolved hepatitis B virus infection was associated with outcomes in patients with previously untreated, HBsAg-negative diffuse…
Bacterial orbital infection leading to orbital exenteration: a case series.
This case series describes three people who underwent orbital exenteration for bacterial infection. Two infections arose from odontogenic sources; the third was periorbital/orbital necrotizing fasciitis associated with…
Within-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
This secondary analysis of a randomized controlled trial evaluated the EuroQol Visual Analogue Scale (EQ-VAS) in adults with post-COVID-19 condition (PCC).
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