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2000 articles

November 202624

Clinical ResearchPlastic Surgery

Technical variation and evidence maturity in gender-affirming peritoneal vaginoplasty: a systematic review.

This systematic review examined technical approaches, indications, and evidence maturity for peritoneal vaginoplasty in gender-affirming surgery. It included 23 full-text studies and five video articles from 14 centers.

J Sex MedNov 6, 2026Read summary
Case ReportPediatrics

Adrenal ganglioneuroma in an adolescent presenting as an incidentaloma: Imaging-pathology correlation and diagnostic challenges: A case report.

A previously healthy 16-year-old male had a right adrenal mass discovered incidentally on CT after a bicycle accident. CT and MRI showed a well-circumscribed lesion with progressive enhancement and no washout or…

Medicine (Baltimore)Nov 6, 2026Read case
Clinical ResearchCardiology

Differential rates of guideline-directed medical therapy modification in C-MIC and control patients: results from the C-MIC II trial.

This analysis of the multicentre, randomised C-MIC II trial examined whether changes in background heart failure medication influenced outcomes in ambulatory patients with chronic non-ischaemic HFrEF receiving…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchOrthopedic Surgery

Effectiveness of a Structured Post-Platelet Rich Plasma Rehabilitation Approach on Pain and Function in Subacromial Pain Syndrome: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether structured rehabilitation after platelet-rich plasma (PRP) adds benefit to conventional physiotherapy for people with subacromial pain syndrome.

Physiother Res IntNov 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Cost-effectiveness of atosiban versus placebo for threatened preterm birth (APOSTEL 8 trial).

This economic evaluation alongside the multicentre randomised APOSTEL 8 trial compared atosiban with placebo for threatened preterm birth at 30+0 to 33+6 weeks’ gestation.

PLoS OneNov 5, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Immediate gastrocnemius responses to intermittent cold compression at different pressure levels in soccer players.

This randomized crossover trial examined immediate responses to intermittent cold compression (ICC) after a soccer-specific fatigue protocol in seven male collegiate soccer players.

PLoS OneNov 5, 2026Read summary
Case ReportVascular Surgery

Occult Compression at the Pectoralis Minor-Second Rib Level After Cervical and First Rib Resection for Thoracic Outlet Syndrome: A Case Report.

A 29-year-old woman with neurogenic thoracic outlet syndrome associated with a cervical rib continued to have symptoms after supraclavicular cervical and first rib resection.

JBJS Case ConnectNov 5, 2026Read case
Case ReportOphthalmology

Clinical Reasoning: A 68-Year-Old Woman With Bilateral Optic Disc Edema.

A 68-year-old immunocompetent woman presented with headache, vertigo, and diplopia. Examination revealed bilateral optic disc edema.

NeurologyNov 5, 2026Read case
Case ReportAnesthesiology

Stellate Ganglion Block for Treatment of Refractory Sympathetic Storm in Severe Tetanus: A Case Report.

A 67-year-old man developed severe tetanus after a bamboo-skewer puncture wound to his left middle finger; the foreign body remained embedded for 3 days before he removed it himself, and he received no systematic…

Am J Case RepNov 5, 2026Read case
Clinical ResearchOncology (Medical)

Prognostic Value of the Preoperative Systemic Immune-Inflammation Index for Overall Survival After Surgical Resection for Gallbladder Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed whether preoperative systemic immune-inflammation index (SII) is associated with overall survival after gallbladder cancer resection.

J Gastrointest CancerNov 5, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Avascular necrosis of the femur following COVID-19: an updated systematic review.

This systematic review updated evidence on avascular necrosis (AVN) of the femoral head reported after COVID-19. Searches identified 55 studies, comprising four cross-sectional studies, six retrospective studies, and 45…

Arch Orthop Trauma SurgNov 5, 2026Read summary
Case ReportInfectious Diseases

Cutaneous Aspergillosis Among Extremely Preterm Neonates in Neonatal Intensive Care Units - Michigan and New York, 2023-2024.

Cutaneous aspergillosis is a rare, life-threatening fungal infection in neonates, particularly those born extremely preterm (gestational age <28 weeks); outbreaks have been linked to environmental sources of Aspergillus…

MMWR Morb Mortal Wkly RepNov 5, 2026Read case
Case ReportInfectious Diseases

Human granulocytic anaplasmosis acquired in Switzerland: a case report.

A man in his early seventies taking methotrexate for ankylosing spondylitis and with tick exposure developed fever, headache and dizziness, followed by somnolence, dysarthria, ataxia and diplopia.

Swiss Med WklyNov 5, 2026Read case
Case ReportOncology (Medical)

Postoperative Neuromuscular Paresis and Overlap Syndrome Related to Immune Checkpoint Inhibitors: A Case Report.

A patient receiving immune checkpoint inhibitor therapy developed extremity paresis after proximal humerus resection and reconstruction.

JBJS Case ConnectNov 5, 2026Read case
Clinical ResearchOncology (Medical)

A phase 1 study of 4'-thio-2'-deoxycytidine in patients with solid tumors.

This phase 1 dose-escalation study evaluated oral 4′-thio-2′-deoxycytidine (TdCyd) in adults with advanced solid tumors. Twenty-seven patients received treatment on days 1–5 and 8–12 of 21-day cycles.

Cancer Chemother PharmacolNov 5, 2026Read summary
Clinical ResearchPulmonologyOpen access

Effect of remote patient monitoring on PAP adherence and patient-reported outcomes in obstructive sleep apnea: a comparative study.

This prospective, open-label, active-comparator randomized trial compared remote patient monitoring (RPM) with standard care (SOC) in PAP-naive adults with obstructive sleep apnea who owned a smartphone.

Sleep BreathNov 5, 2026Read summary
Clinical ResearchPediatrics

A phase 2 study of tipifarnib in children and young adults with tumors harboring HRAS genomic alterations: NCI-COG Pediatric MATCH trial (APEC1621M).

This phase 2 NCI-COG Pediatric MATCH study evaluated intermittent oral tipifarnib in children and young adults with relapsed or refractory solid tumors carrying specified HRAS mutations.

OncologistNov 5, 2026Read summary
Case ReportOrthopedic Surgery

Anomalous Triceps Muscle Slip as an Unusual Cause of Ulnar Nerve Entrapment in a Division I Baseball Pitcher: A Case Report.

A 19-year-old right-hand-dominant collegiate pitcher developed medial elbow pain, reduced pitching velocity, and ulnar-sided numbness after a bullpen session.

JBJS Case ConnectNov 5, 2026Read case
Clinical ResearchGastroenterology

Clinical Evidence for Adding Chaiqin Chengqi Decoction to Acute Pancreatitis Care: A Systematic Review and Meta-analysis of Randomized Trials.

This systematic review and meta-analysis assessed randomized trials of Chaiqin Chengqi Decoction (CQCQD) added to conventional care for acute pancreatitis. Nineteen trials involving 1,824 participants were included.

J Vis ExpNov 5, 2026Read summary
Case ReportNeurosurgery

Spontaneous Colonic Migration of a Ventriculoperitoneal Shunt Catheter.

A 63-year-old man developed fever, somnolence, and elevated inflammatory markers 2.5 years after ventriculoperitoneal shunt placement.

Am J Case RepNov 5, 2026Read case
Clinical ResearchCardiology

Clinical outcomes in various coronary artery bypass grafting techniques: A systematic review and network meta-analysis.

This systematic review and frequentist network meta-analysis compared conventional, minimally invasive, and robotic coronary artery bypass grafting (CABG), including nine sub-techniques, using observational studies and…

PLoS OneNov 5, 2026Read summary
Clinical ResearchOncology (Medical)

Long-term effects of a parenting program for advanced cancer: A randomized controlled trial.

This randomized controlled trial evaluated a telephone-delivered, five-session parenting education program for parents with advanced, non-curable cancer who were raising children.

Palliat Support CareNov 5, 2026Read summary
Case ReportHematology

A case report of ultra-rare SMARCD2 deficiency and review of the literature.

The report describes a patient with congenital neutropenia due to specific granule deficiency type 2, a syndromic autosomal recessive disorder associated with loss-of-function variants in SMARCD2.

Immunol ResNov 5, 2026Read case
Clinical ResearchAnesthesiology

Thoracic epidural versus paravertebral blockade for reducing chronic post-thoracotomy pain (TOPIC-2): open label, parallel group, superiority, multicentre, randomised controlled trial.

This open-label, multicentre, parallel-group superiority randomised trial compared perioperative paravertebral blockade with thoracic epidural in adults undergoing thoracotomy at 15 UK centres.

BMJNov 5, 2026Read summary

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