Trending archive
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1303 articles
October 20264
Online stepped care for the treatment of posttraumatic stress disorder: A randomized controlled noninferiority trial.
This randomized controlled non-inferiority trial compared online stepped care with telehealth cognitive processing therapy (CPT) in 84 adults with PTSD or subthreshold PTSD.
Who is getting better in treatment? Dynamics in risk processes as a signature of short-term suicide treatment response.
This analysis of adults receiving up to 12 sessions of suicide-focused therapy within a randomized clinical trial examined whether weekly patterns in suicide risk and resilience differed according to suicide attempts…
Sensory processing and executive functioning interaction in neurodevelopmental disorders and at-risk conditions: A systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between sensory processing (SP) and executive functioning (EF) in children and adolescents aged 0–18 with neurodevelopmental disorders or at-risk…
Interventions to address loneliness and social isolation in community-dwelling older adults: an umbrella review.
This umbrella review synthesised and appraised systematic reviews, scoping reviews, and meta-analyses of interventions for loneliness and social isolation among community-dwelling older adults.
September 202620
When seizure control comes at a cost: valproic acid-induced necrotising pancreatitis in a patient receiving antiepileptic polypharmacy.
A man in his late 20s with psychiatric and metabolic comorbidities developed acute necrotising pancreatitis while on antiepileptic polypharmacy, including valproic acid.
Effectiveness of psychosocial counselling on treatment adherence among patients with a new tuberculosis diagnosis in primary care: a study protocol for a cluster-randomised controlled trial.
This study protocol outlines a cluster-randomised controlled trial aimed at evaluating the effectiveness of psychosocial counselling on treatment adherence among newly diagnosed tuberculosis patients in primary care…
Association between personal birth companion and maternal mental health in low- and middle-income countries: a systematic review.
This systematic review examined the impact of personal birth companions on maternal mental health during labor and postpartum in low- and middle-income countries.
Doing the groundwork at home, working through it together: patient experiences of blended cognitive therapy for PTSD in routine care.
This qualitative study explored patient experiences with blended trauma-focused cognitive therapy (bTF-CT) for PTSD in routine care, involving 11 participants.
Sex differences in the efficacy, acceptability, and tolerability of antipsychotics in people with acute schizophrenia: individual participant data pairwise, dose-response, and network meta-analyses.
This individual participant data pairwise, dose-response, and network meta-analysis examined sex differences in antipsychotic efficacy, acceptability, and tolerability in adults with acute schizophrenia.
Pharmacological interventions for acute major depression and bipolar depression with mixed features: A systematic review and dose-related network meta-analysis across different age groups.
This systematic review and dose-related network meta-analysis compared pharmacological treatments with placebo or other treatments for acute bipolar depression and major depression with mixed features, including…
Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report.
A 47-year-old man presented with cognitive decline, gait disturbance, and urinary incontinence. Imaging revealed ventricular enlargement and high signal intensity in the medial temporal lobes.
Epigenetic Programming of Stress-Response Systems: A Systematic Review of How Early Life Stress Shapes Developmental Trajectories of Mental Health.
This systematic review examines how early life stress (ELS) influences mental health development through epigenetic mechanisms, particularly DNA methylation, in 14 empirical human studies.
Designing Youth Early Intervention in Psychosis Services: A Secondary Framework Synthesis of Organisational Recommendations.
This systematic review synthesized organizational recommendations from 26 international guidelines on early intervention in psychosis (EIP) for youth.
The Effect of Emotional Freedom Techniques on Death Anxiety and Cancer-Related Anxiety in Patients Undergoing Oncological Surgery: A Randomized Controlled Trial.
This randomized controlled trial examined the impact of emotional freedom techniques (EFT) on death anxiety and cancer-related anxiety in 120 patients undergoing oncological surgery.
Effect of strengths-based, tiered, accessible resources and supports (STARS) for Kids project, a codesigned hybrid service delivery framework to identify and support child development, parent mental health and psychosocial needs among parents and carers of children aged 6 months to 3 years: a randomised controlled trial protocol.
This randomized controlled trial protocol evaluates the STARS for Kids model, designed to enhance early identification and support for child development and parental mental health among parents of children aged 6 months…
Recurrent serotonin syndrome during low-dose venlafaxine treatment in a patient with reduced CYP2D6 activity.
A man in his late 70s with transthyretin amyloidosis experienced recurrent serotonin syndrome while on low-dose venlafaxine treatment.
Acceptability and Feasibility of a Virtual Family-Based Single-Session Intervention for Young Teens at High Risk for Substance Use Disorder: Single-Arm Pilot Trial.
This single-arm pilot trial evaluated a virtual family-based single-session intervention (SSI) for young teens aged 12-14 at high risk for substance use disorder (SUD).
Dual Sensory Impairment and Depressive Symptoms: Association and Pathways in Three Cohorts and a Meta-Analysis.
This meta-analysis examined the relationship between dual sensory impairment (DSI) and depressive symptoms in three aging cohorts: CHARLS, HRS, and ELSA.
Exploring treatment moderators in a randomized clinical trial of virtual reality-based vs. standard cognitive behavioral therapy for paranoia.
This randomized clinical trial secondary analysis explored whether clinical and sociodemographic characteristics moderated response to virtual reality-based cognitive behavioral therapy for psychosis (VR-CBTp) versus…
Helping or controlling? A multi-method case study of a mother-daughter dyad and their interactions during trauma-focused therapy.
This case study involved a 14-year-old girl undergoing intensive trauma-focused therapy, assessed alongside her mother over five weeks.
A comparison of the efficacy of cognitive-behavioral stress management and acceptance and commitment therapy on the quality of life and fatigue of caregivers of patients with cancer: a randomized controlled trial.
This randomized controlled trial compared the efficacy of cognitive behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the quality of life and fatigue in 66 caregivers of cancer patients.
Beyond β-amyloid: transthyretin cerebral amyloid angiopathy.
A 44-year-old man presented with recurrent upper-limb and perioral sensory symptoms, later identified as transient focal neurological episodes.
A machine learning-based ecological momentary intervention for mental health promotion in youth: a micro-randomized trial.
This micro-randomized trial investigated the effects of machine learning (ML)-based ecological momentary interventions (EMIs) on mental health outcomes in 49 youth participants.
Therapeutic drug monitoring-guided management of venlafaxine overdose in an adolescent: a case report.
An adolescent presented with severe venlafaxine overdose, exhibiting tachycardia, mydriasis, and generalized tonic-clonic seizures. Initial plasma levels were 7800 ng/mL, significantly above therapeutic limits.
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