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2000 articles
October 202624
Neoadjuvant Therapy for Gastric Adenocarcinoma with Signet Ring Cells: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed neoadjuvant chemotherapy followed by surgery versus upfront gastrectomy in adults with signet ring cell-containing gastric cancer.
Comparative perioperative and oncological outcomes of the da Vinci Xi versus Si robotic surgical systems in rectal cancer surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis compared perioperative and oncological outcomes with da Vinci Xi versus Si systems in rectal cancer surgery.
Unusual Isolated Thymic Relapse of Neuroblastoma Detected By 123 I-mIBG Scintigraphy in a Pediatric Patient.
A pediatric patient with neuroblastoma developed an anterior mediastinal mass representing thymic relapse. The mass showed intense uptake on 123I-meta-iodobenzylguanidine (123I-mIBG) scintigraphy, which detected the…
Sarcoid-like Reaction With Pleural Involvement After Neoadjuvant Chemo-immunotherapy For Lung Cancer: A Rare Mimic of Disease Progression.
A patient with stage IIA lung adenocarcinoma developed new diffuse pleural, pulmonary, and nodal FDG uptake on 18F-FDG PET/CT after three cycles of neoadjuvant nivolumab plus cisplatin-pemetrexed, while the primary…
[ 18 F]AlF-NOTA-FAPI-04 PET/CT for Incidental Detection of a Benign Phyllodes Tumor in a Patient With Prior Colon Cancer.
A 68-year-old woman with a history of colon cancer had a right breast nodule detected incidentally on routine contrast-enhanced CT, where it showed moderate enhancement.
Comparative efficacy of interventions for preventing chemotherapy-induced alopecia: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared preventive interventions for chemotherapy-induced alopecia in cancer patients, including 12 randomized trials with 736 participants and nine intervention groups.
Efficacy and safety of ifupinostat in relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase 2 study.
This multicenter, single-arm phase 2 study evaluated intravenous ifupinostat monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma after at least two prior systemic therapy lines.
Premature treatment cessation in pediatric acute myeloid leukemia due to excessive toxicity: clinical experiences and patient outcomes - a case series.
A Dutch national database review identified seven children with acute myeloid leukemia (AML) whose chemotherapy was stopped early because of excessive toxicity. Severe fungal infection prompted discontinuation in five.
Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.
This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…
Conventional Skull Base Chordoma in a Ugandan Adult Male, Presenting with Prolonged Headache: A Case Report.
A 49-year-old man had more than a year of intermittent, progressively worsening headache and reported an episode of facial numbness, although facial sensation and the remainder of his neurological examination were…
Pacak-Zhuang syndrome with EPAS1 p.Pro531Leu somatic variant: one case report and literature review.
A 4-year-old girl presented with recurrent hypertension, polycythemia and renal hilar masses. Imaging, biochemical testing and genetic analysis of paraffin-embedded tissue confirmed Pacak-Zhuang syndrome with a somatic…
An Integrated Approach to MSI-High Colorectal Cancer Therapy in a Young Patient: A Clinical Case.
A 16-year-old male underwent appendectomy for presumed appendicitis, but persistent postoperative bowel obstruction led to CT detection of a descending-colon tumor and emergency Hartmann’s procedure.
PD-1/ PD-l1 Inhibitors and Stereotactic Radiosurgery for Brain Metastases: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed efficacy and toxicity when PD-1/PD-L1 inhibitors were combined with stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) for…
Non-Relapse Mortality With Bispecific Antibodies in Hematologic Malignancies: A Dual Systematic Review and Pharmacovigilance Analysis.
This systematic review and meta-analysis, supplemented by a pharmacovigilance analysis of FAERS, assessed non-relapse mortality (NRM) and other toxicities with bispecific antibodies in relapsed/refractory hematologic…
Effectiveness of local ablative therapy combined with first-line tyrosine kinase inhibitors in epidermal growth factor receptor-mutated oligometastatic non-small cell lung cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed local ablative therapy (LAT) plus first-line tyrosine kinase inhibitors (TKIs) versus TKI alone in patients with EGFR-mutated oligometastatic non-small cell lung cancer.
Digital supportive care in prostate cancer: a systematic review.
This systematic review synthesised evidence on the perspectives and requirements of people affected by prostate cancer for patient-facing digital supportive care.
Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.
A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…
Akkermansia muciniphila attenuates macrophage efferocytosis to enhance anti-PD-1 efficacy in microsatellite-stable colorectal cancer.
This study examined whether Akkermansia muciniphila (Akk) could improve anti-PD-1 activity in microsatellite-stable (MSS) colorectal cancer.
WIN-MTB-2024002 - WIN International Molecular Tumor Board: A 52-year-old female with unmeasurable Stage IIIc colon cancer.
A 52-year-old woman with stage IIIc colon cancer had KRAS, TP53, IDH1, and APC mutations, high tumor PD-L1 expression, and elevated VEGFR1 and VEGFR3.
Presumed oxaliplatin-related Guillain-Barré syndrome: A case report and review of chemotherapy-related Guillain-Barré syndrome.
A 77-year-old woman with metastatic cholangiocarcinoma and colorectal carcinoma developed rapidly progressive, symmetric ascending motor weakness about 2 weeks after her last cycle of gemcitabine, oxaliplatin…
Firmonertinib in advanced non-small cell lung cancer with epidermal growth factor receptor P-loop and αC-helix compressing mutations.
The phase 1b FURTHER study evaluated first-line firmonertinib in patients with metastatic EGFR P-loop and αC-helix compressing (PACC)-mutant non-small cell lung cancer. Patients were randomized to 160 mg or 240 mg daily.
Acute colonic variceal bleeding treated with coil-assisted retrograde transvenous obliteration following atezolizumab-bevacizumab therapy for advanced hepatocellular carcinoma: A case report.
A 66-year-old man with alcohol-related cirrhosis and advanced hepatocellular carcinoma developed hematochezia the day after starting atezolizumab plus bevacizumab.
Influenza A (H1N1) virus infection complicated by checkpoint inhibitor pneumonitis: A case report.
After neoadjuvant immunotherapy, a patient developed respiratory dysfunction and progressive pulmonary lesions. Imaging and positive influenza A (H1N1) testing, interpreted alongside the immunotherapy history and…
AI-Assisted Molecular Review Refines SMO Inhibitor Candidacy in SHH Medulloblastoma.
A 40-year-old woman with unresectable SHH-activated medulloblastoma received standard chemoradiation, but post-treatment imaging was equivocal.
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