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412 articles
July 202615
Prevalence and types of insulin-pump-related skin complications in children and adolescents with type 1 diabetes: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence and types of insulin-pump-related skin complications in children and adolescents with type 1 diabetes.
From Self-Mutilation to Genetic Diagnosis: A Case Report of Hereditary Sensory and Autonomic Neuropathy Type VIII Illuminating the Role of a Rare PRDM12 Mutation.
A 10-month-old female presented with Hereditary Sensory and Autonomic Neuropathy Type VIII, characterized by congenital insensitivity to pain, self-mutilation, and autonomic dysfunction.
Cost-Utility Analyses of Systemic Treatments for Psoriasis and Psoriatic Arthritis in the UK: A Systematic Review of Modelling Methods.
This systematic review analyzed cost-utility analyses of systemic treatments for psoriasis and psoriatic arthritis in the UK.
Squamoid Eccrine Ductal Carcinoma: Case Series of a Rare, Potentially Aggressive Skin Cancer Associated With Immunosuppression.
In this single-centre retrospective series, 10 patients with squamoid eccrine ductal carcinoma (SEDC) were identified; 9 were immunocompromised, including 6 solid-organ transplant recipients and 3 patients with…
Synergistic Effects of Intense Pulsed Light and Glycolic Acid on Photoaging and the Involvement of CD26 in Photoprotection.
This prospective, randomized split-face study assessed combined intense pulsed light and glycolic acid (IAG) versus IPL alone in 20 people with photoaged skin, alongside mouse and fibroblast experiments examining CD26.
Dupilumab treatment improves linear growth and bone biomarkers in children with atopic dermatitis: Post hoc analysis of a phase 3 randomized, placebo-controlled clinical trial and an open-label extension study.
This post hoc analysis of a phase 3 randomized, placebo-controlled trial and its open-label extension examined height and bone alkaline phosphatase (BALP) in children aged 6 to 11 years with severe atopic dermatitis.
Dupilumab-Associated Erythema Multiforme-Like Eruption With Lichenoid Histology in a Paediatric Patient: A Case Report.
A 5-year-old boy with eczema developed erythematous targetoid papules and plaques on his upper and lower limbs while receiving dupilumab.
Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46-Year-Old Man.
A 46-year-old incarcerated man with chronic hepatitis C and a history of intravenous drug use developed a rapidly progressive, pruritic eruption across the scalp, trunk, and limbs, with patchy scalp hair loss and…
Stapokibart provides significant improvements in signs and symptoms of atopic dermatitis irrespective of prior systemic treatment: a post-hoc analysis of a phase 3 trial.
This post-hoc analysis of a phase 3 trial evaluated the efficacy and safety of stapokibart in adults with moderate-to-severe atopic dermatitis, both with and without prior systemic treatment.
Myxoid Variant of Primary Cutaneous Anaplastic Large Cell Lymphoma Mimicking Soft Tissue Sarcoma: Diagnostic Pitfalls and Literature Review.
A 40-year-old man presented with a slowly enlarging ulcerated mass on his left thigh, interpreted radiologically as a superficial soft tissue sarcoma.
Alpelisib for TEK- and PIK3CA-Related Venous Malformations: A Systematic Review.
This systematic review examined alpelisib treatment in 47 patients with molecularly diagnosed TEK- or PIK3CA-related venous malformations.
The combination of 1064 nm pulsed Nd:YAG laser and ALA-PDT for Phymatous Rosacea.
Rosacea is a common chronic inflammatory disease. Among its four subtypes, phymatous rosacea predominantly affects middle-aged and elderly men and is characterized by hyperplasia and hypertrophy of both fibrous tissue…
Assessing the Adverse Events of Roflumilast and Tapinarof Use in Pediatric and Young Adult Patients with Atopic Dermatitis: A Systematic Review.
This systematic review evaluated the adverse events associated with roflumilast and tapinarof in pediatric and young adult patients with atopic dermatitis.
Clinicopathologic and molecular characteristics of acral melanomas harboring RARA fusions.
The report describes two adults with acral cutaneous melanomas on the feet, both harboring RARA fusions. Tumors varied in spindle, epithelioid, and occasional rhabdoid morphology and had low tumor mutational burden.
Benzalkonium Chloride in Eye Drops Causing Allergic Contact Dermatitis: A Case Series.
The report describes three patients who developed allergic contact dermatitis (ACD) associated with benzalkonium chloride (BAK) in ophthalmic drops. BAK is a commonly used preservative in eye-drop formulations.
June 20269
Severe cutaneous adverse reactions associated with systemic antibiotics in acne vulgaris: a systematic review.
Acne vulgaris (AV) is an inflammatory disorder of the pilosebaceous unit commonly managed with systemic antibiotics. Since antibiotics are known triggers of severe cutaneous adverse drug reaction (SCARs), patients with…
A novel JAK1 mutation identified in a patient with severe atopic dermatitis phenotype: Mechanistic insights and IL-4Rα targeted therapy.
A child with early-onset severe atopic dermatitis presented with eosinophilia, elevated IgE, and growth retardation. Genetic analysis identified a novel JAK1 gain-of-function mutation (p.L783F).
Triggering of Koebner Phenomenon by Picosecond Laser in a Psoriatic Patient: Clinical and Immunopathologic Insights.
A 58-year-old woman with well-controlled plaque psoriasis received 755-nm picosecond alexandrite laser treatment for seborrheic keratoses on her back and lower waist.
Atypical Grover Disease Associated With Merkel Cell Carcinoma: A Novel Paraneoplastic Presentation.
A 63-year-old man presented with four months of generalized, pruritic papules. Biopsy showed focal intraepidermal acantholysis and dyskeratosis with patchy vacuolar interface change; direct immunofluorescence was…
Intralesional human papillomavirus vaccination for cutaneous verrucae: a systematic review and meta-analysis of therapeutic efficacy.
This systematic review and meta-analysis evaluated the efficacy of intralesional human papillomavirus (HPV) vaccination for treating cutaneous warts in patients with chronic or persistent lesions.
Secukinumab biosimilar BAT2306 versus reference secukinumab in patients with moderate-to-severe plaque psoriasis: a multicentre, double-blind, randomised, active-controlled, phase 3 trial.
This phase 3, multicentre, double-blind, randomised trial compared the biosimilar BAT2306 to reference secukinumab in 502 patients with moderate-to-severe plaque psoriasis.
Efficacy, Safety, Quality of Life, and Adherence of Dupilumab in Pediatric Atopic Dermatitis: A Systematic Review.
This PRISMA-guided systematic review assessed dupilumab efficacy, safety, quality of life, and adherence in children aged 0–12 years with moderate-to-severe atopic dermatitis.
Efficacy of Intralesional Bevacizumab Versus Intralesional Triamcinolone Acetonide Injection in the Treatment of Keloids: A Randomized Clinical Trial.
This randomized clinical trial compared monthly intralesional triamcinolone acetonide (TAC) with bevacizumab over three sessions in 28 adults with post-traumatic keloids.
Efficacy of current approaches to non-invasive diagnosis of skin cancer and the potential impact of artificial intelligence: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of non-invasive skin cancer diagnostic methods, focusing on artificial intelligence (AI) tools.
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