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33 articles
November 202613
Effects on Sleep Quality and Bioelectrical Parameters of Cellular Health After Administration of a Plant Protein Supplement Combined with Ashwagandha and Rhodiola: A Randomized Controlled Trial.
This randomized, double-blind, placebo-controlled trial tested 30 days of plant protein combined with ashwagandha and rhodiola in adults aged 35–70 years. Of 100 participants assigned, 61 completed sleep assessments.
Efficacy and safety of apixaban versus rivaroxaban in acute venous thromboembolism: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared apixaban with rivaroxaban for acute venous thromboembolism in adults.
Impact of artificial intelligence-assisted health management on blood pressure and self-management efficacy in older adults with hypertension.
This randomized controlled trial compared AI-assisted health management with routine care in older adults with hypertension. The intervention included intelligent monitoring, early warning and proactive intervention.
Discontinuation of renin-angiotensin system inhibitors before non-cardiac surgery: a meta-analysis.
This systematic review and meta-analysis of five randomized controlled trials compared discontinuation with continuation of renin-angiotensin system inhibitors before non-cardiac, non-vascular surgery.
Effectiveness of nurse-led hypertension interventions on retention, adherence, and blood pressure control among adults in low- and middle-income countries: A systematic review.
This systematic review assessed nurse-led hypertension interventions in primary care among adults in low- and middle-income countries, examining retention, medication adherence, and blood pressure.
Systemic corticosteroids in critical illness: an evidence-based framework for clinical decision-making.
This systematic review qualitatively synthesized randomized trials, reviews, and meta-analyses to develop a decision framework for systemic corticosteroids in severe community-acquired pneumonia (sCAP), acute…
Pseudo-Metabolic Alkalosis: A Hidden Laboratory Pitfall With Elevated LDH.
A 33-year-old man presented with progressive exertional dyspnea, syncope, and paresthesia. Testing showed pancytopenia, macrocytosis, LDH >3600 U/L, low haptoglobin, and vitamin B₁₂ <68 pg/mL, consistent with pernicious…
Associations of Health Literacy and eHealth Literacy With Patient Portal Access and Use: Systematic Review.
This systematic review synthesized quantitative studies of health literacy and eHealth literacy in relation to real-world patient portal access and use among adults.
Fucoidan as an anti-inflammatory and immunomodulatory agent in humans: a systematic review of clinical evidence and translational potential.
This systematic review assessed human interventional studies of fucoidan supplementation for inflammatory, immune, metabolic, and tumour-related outcomes.
Proton-pump inhibitor-induced severe hypomagnesemia presenting with seizure and functional hypoparathyroidism: A diagnostic challenge in long-term acid suppression therapy.
A 68-year-old man taking omeprazole 40 mg/day for 8 years presented with a generalized tonic-clonic seizure and neuromuscular irritability.
Drug-drug interactions between statins and antibiotics: A systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis assessed observational evidence on muscle toxicity when statins are used with interacting antibiotics, compared with statin therapy alone.
Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed brief, freely available cognitive tests for detecting cognitive impairment, including mild cognitive impairment and dementia, in adults aged 55 years and older in…
Effects of Integrated Multicomponent Care on Older Adults With Frailty or Pre-Frailty: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed integrated multicomponent care (IMC) for older adults with frailty or pre-frailty, including evidence from 20 randomised and quasi-experimental studies.
October 202611
The experience of family caregivers when their loved one is home hospitalized: a mixed methods analysis of a randomized controlled trial.
This mixed-methods analysis examined family caregivers of patients in a multicentre randomised controlled trial of rural home hospital care in the USA and Canada.
Digital Health Services and Healthcare Management Outcomes: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed digital health services—including telemedicine, telemonitoring, virtual consultations, and remote care—against conventional care across 21 eligible studies.
Efficacy and Safety of Nafamostat Mesilate Injection in Patients Receiving Continuous Renal Replacement Therapy: A Meta-Analysis.
This meta-analysis assessed the efficacy and safety of nafamostat mesilate injection versus no anticoagulation in patients receiving continuous renal replacement therapy (CRRT).
Oral Potassium Supplementation Lowers Clinic Blood Pressure in Untreated Primary Hypertension-Systematic Review and Meta-Analysis of Randomized Trials.
This systematic review and meta-analysis assessed oral potassium supplementation versus placebo, sodium chloride, or no treatment in adults with untreated primary hypertension.
Risk factors for Post-COVID-19 Syndrome in patients hospitalized for severe acute respiratory syndrome: systematic review and meta-analysis.
This systematic review and meta-analysis examined factors associated with post-COVID-19 syndrome among patients discharged after hospitalization for severe acute respiratory syndrome.
Community Health Worker Interventions Addressing Social Determinants of Health in Chronic Disease: A Systematic Review.
This systematic review assessed US randomized and quasi-experimental studies of patient-facing community health worker (CHW) interventions addressing at least one social determinant of health among adults with chronic…
Chlorhexidine within a standardized oral-care bundle for the prevention of ventilator-associated pneumonia: a pragmatic cluster-randomized crossover trial in six medical intensive care units.
This pragmatic cluster-randomized crossover trial in six adult medical ICUs at one Indian tertiary-care hospital compared a standardized oral-care bundle with the same bundle plus 0.12% chlorhexidine (CHX) in adults…
Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial.
This randomized controlled trial compared handgrip and knee-extension isometric training with control in 67 adults with controlled hypertension receiving antihypertensive medication.
A 58-Year-Old Woman with Abdominal Pain, Fever, and Cough.
A 58-year-old woman presented with fever, abdominal pain, and a nonproductive cough. The report describes a diagnostic evaluation using focused history, physical examination, and testing, with the differential diagnosis…
E-Cigarettes with and without Behavioral Support for Smoking Cessation.
This randomized controlled trial compared an e-cigarette starter pack alone, the starter pack plus multisession telephone-based behavioral support, and automated supportive messages among people who smoked and were…
The association between e-cigarette use and dyslipidemia: A systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis examined observational evidence on exclusive e-cigarette use and blood lipids in adults. Seven studies from four countries included 25,690 participants.
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