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1602 articles
October 202624
Rare origin of the right inferior phrenic artery from the anterior inferior pancreaticoduodenal artery in a patient with hepatocellular carcinoma.
A woman in her 80s with ruptured hepatocellular carcinoma underwent emergency transcatheter arterial embolization. CT did not show the right inferior phrenic artery (RIPA) at its usual origins and suggested a source in…
Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression.
This observational follow-up examined brain volumes and later negative emotionality in 109 infants born to mothers who had participated in a randomized clinical trial of brief interpersonal psychotherapy for prenatal…
Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.
This mixed methods study evaluated recruitment, engagement, completion, and participant experiences in Dialysafe, a digital education and peer-mentoring intervention at 10 hemodialysis centers.
Global Prevalence of Adherence to Antihypertensives and Associated Moderating Factors Among Adults With Hypertension: A Meta-Analysis.
This systematic review and meta-analysis estimated global adherence to antihypertensive medication among adults with hypertension.
Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.
This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.
Psychological Stress and the Diurnal Patterns of Sodium Excretion and Blood Pressure: Results From the SABRE Study.
The SABRE study examined whether urinary sodium responses to mental stress were associated with day–night sodium excretion patterns and systolic blood pressure (BP) dipping in apparently healthy adults.
Effectiveness of Discrete Strategies and Implementation Bundles for Improving Clinician Prescription of Clinical Practice Guideline-Recommended Medications for Atherosclerotic Occlusive Disease: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed randomized trials of strategies to improve prescription of guideline-strongly-recommended medications for adults with atherosclerotic occlusive disease.
AI-Assisted Molecular Review Refines SMO Inhibitor Candidacy in SHH Medulloblastoma.
A 40-year-old woman with unresectable SHH-activated medulloblastoma received standard chemoradiation, but post-treatment imaging was equivocal.
Optimal exercise modalities and doses for blood pressure management in adults with prehypertension and hypertension: A systematic review and Bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared structured exercise modalities and estimated doses for blood pressure reduction in adults with prehypertension or stage 1 or 2 hypertension.
SGLT2 inhibitors in diabetic biopsy proven MASH patients: A systematic review and meta-analysis.
This systematic review and random-effects, single-arm meta-analysis assessed SGLT2 inhibitors in patients with diabetes and biopsy-proven MASH. Seven trials contributed 110 patients receiving the intervention.
Evaluating Long-Term Effectiveness and Safety of Glaucoma Surgical Innovations: A Systematic Review.
This systematic review assessed long-term effectiveness, safety reporting, and study quality for glaucoma surgical innovations introduced since 2004.
Planned Antihypertensive Deprescribing in Long-Term Care Residents: A Systematic Review of Randomized Evidence.
This systematic review synthesized randomized and cluster-randomized studies of planned antihypertensive deprescribing among long-term care residents.
Effect of Vasopressin Infusion Rate on Vancomycin Dose Adjustment in Pediatric Central Diabetes Insipidus: Grand Round/A Case Study.
A 9-month-old infant with trauma-associated central diabetes insipidus received continuous arginine vasopressin (AVP) and vancomycin for suspected postoperative surgical-site infection.
Firmonertinib in advanced non-small cell lung cancer with epidermal growth factor receptor P-loop and αC-helix compressing mutations.
The phase 1b FURTHER study evaluated first-line firmonertinib in patients with metastatic EGFR P-loop and αC-helix compressing (PACC)-mutant non-small cell lung cancer. Patients were randomized to 160 mg or 240 mg daily.
Effects of treadmill exercise with and without vertical traction on gait, pain, disability, trunk proprioception, and depression in patients with chronic mechanical low back pain: A randomized controlled trial.
This randomized controlled trial compared treadmill exercise with vertical traction and partial body weight support (VT+TE), treadmill exercise alone, and core stabilization in 45 patients with chronic mechanical low…
Aberrant amygdala subregion volumes in youth at high risk for bipolar disorder predict antidepressant-induced adverse events.
This randomized controlled trial examined whether baseline amygdala subregion volumes were associated with antidepressant-related adverse events in 105 youth with a first-degree relative with bipolar I disorder and…
Cochlear Implantation and Cognitive Function in Adults: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed cognitive test scores before and at least 6 months after cochlear implantation in adults with postlingual hearing loss.
Akkermansia muciniphila attenuates macrophage efferocytosis to enhance anti-PD-1 efficacy in microsatellite-stable colorectal cancer.
This study examined whether Akkermansia muciniphila (Akk) could improve anti-PD-1 activity in microsatellite-stable (MSS) colorectal cancer.
Primary Hepatic Neuroendocrine Neoplasms: Systematic Review and Expert Pathologist Reappraisal Using the WHO 6th Edition Framework.
Primary hepatic neuroendocrine neoplasms (PHNENs) are exceedingly rare. Published evidence often lacks adequate clinicopathological support for a primary hepatic origin and uses inconsistent historical terminology.
Comparative Efficacy and Safety of Systemic Immunomodulatory Therapies for Non-Infectious Uveitis: A Systematic Review With Pairwise and Network Meta-Analyses.
This systematic review and network meta-analysis compared systemic immunomodulatory therapies for non-infectious uveitis (NIU), including evidence from seven studies with 992 participants: six randomised trials and one…
The effects of sodium reduction and the DASH diet on ambulatory blood pressure: overall and race-stratified results from the DASH-Sodium trial.
This randomized feeding trial examined ambulatory blood pressure (ABP) responses to sodium reduction and the DASH diet in 335 participants, 58% of whom self-identified as Black.
Efficacy and safety of baxdrostat in the management of uncontrolled hypertension: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed baxdrostat versus placebo in randomized controlled trials involving patients with uncontrolled hypertension.
Prognostic value of measuring LSC frequency in AML: a systematic review and meta-analysis.
This systematic review and reconstructed individual patient data meta-analysis assessed whether leukemia stem cell (LSC) measurements predict outcomes in patients with acute myeloid leukemia at diagnosis or in…
Blood-based biomarkers in patients with recurrent, persistent, or metastatic endometrial cancer treated with olaparib and cediranib: Results from NRG-GY012.
This biomarker analysis of the phase 2 NRG-GY012 clinical trial assessed blood-based markers and outcomes among patients with recurrent, persistent, or metastatic endometrial cancer treated with olaparib, cediranib, or…
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