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1602 articles

November 202624

Clinical ResearchOrthopedic Surgery

Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): a randomized controlled trial.

This multicentre randomized controlled trial tested whether app-based cognitive behavioural therapy (CBT) reduced persistent postsurgical pain in adults with operatively treated extremity fractures at 11 hospitals in…

CMAJNov 9, 2026Read summary
Case ReportNeurosurgeryOpen access

Multifocal intradural extramedullary myxopapillary ependymoma of the spine.

A 34-year-old man presented with sudden severe non-radicular low-back pain but no neurological deficit. MRI showed multiple enhancing intradural extramedullary lesions from T12-L1 to S1; the dominant T12-L1 lesion…

J Cancer Res Clin OncolNov 9, 2026Read case
Clinical ResearchEndocrinology

Machine Learning Models for Glycemic Prediction in Type 1 and Type 2 Diabetes: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed machine-learning models predicting glucose values or glycemic events in people with type 1, type 2, mixed, or unclear diabetes.

J Med Internet ResNov 9, 2026Read summary
Clinical ResearchPediatricsOpen access

Evening amber-lensed glasses in combination with a prescribed wake time advance circadian timing in adolescents with delayed sleep-wake phase disorder.

This 3-week randomized controlled trial tested evening amber-lensed glasses plus a prescribed stable wake time in adolescents aged 14.3–18.1 years with delayed sleep-wake phase disorder (DSWPD).

J Clin Sleep MedNov 9, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Operative versus nonoperative management of olecranon fractures in older adults: a systematic review and meta-analysis.

This systematic review and meta-analysis compared operative with nonoperative management of displaced olecranon fractures in older adults.

Arch Orthop Trauma SurgNov 9, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Pertuzumab in HER2-positive breast cancer: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis pooled 8 randomized controlled trials involving 8367 patients with HER2-positive breast cancer to assess pertuzumab-based regimens.

Breast Cancer Res TreatNov 9, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Dose-dense neoadjuvant bi-weekly nab-paclitaxel followed by epirubicin-cyclophosphamide versus bi-weekly docetaxel followed by epirubicin-cyclophosphamide in patients with HR+/HER2- early breast cancer: a multicentre, randomised, phase III trial.

This multicentre, randomised phase III trial at three hospitals in China compared dose-dense neoadjuvant nab-paclitaxel with docetaxel, each followed by epirubicin-cyclophosphamide, in patients with early HR+/HER2−…

Breast Cancer Res TreatNov 9, 2026Read summary
Clinical ResearchPsychiatry

Altered effective connectivity during cognitive distancing in cognitive behavioral therapy nonresponders with depression.

This clinical trial analysis examined whether pretreatment brain connectivity during cognitive distancing was associated with cognitive behavioral therapy (CBT) response in 77 outpatients with major depressive disorder.

Psychol MedNov 9, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

The Effect of Exercise Training on Individuals With Osteoporotic Vertebral Fracture: A Randomized Controlled Trial.

This single-centre, open-label randomised controlled trial evaluated a 12-week supervised exercise programme in adults with osteoporotic vertebral fractures.

Physiother Res IntNov 8, 2026Read summary
Clinical ResearchOrthopedic Surgery

Paraspinal Muscle Quality and Functional Outcomes Following Lumbar Fusion: A Systematic Review.

This systematic review examined whether preoperative and postoperative paraspinal muscle quality is associated with patient-reported outcomes after lumbar interbody fusion, and whether findings differ between minimally…

Musculoskeletal CareNov 8, 2026Read summary
Clinical ResearchOrthopedic Surgery

A Pilot Clinical and Experimental Study of Type I Collagen Matrix Implantation Versus Microfracture for Knee Cartilage Defects.

This prospective, randomized, exploratory pilot translational study compared Type I collagen matrix implantation with microfracture for knee cartilage defects, combining rat experiments with a randomized, single-blind…

Med Sci MonitNov 8, 2026Read summary
Case ReportOrthopedic Surgery

Fresh Osteochondral Allograft Transplantation as a Salvage Procedure Following Failed Fixation of Osteochondritis Dissecans of the Lateral Femoral Condyle: A Case Report.

A 19-year-old competitive athlete developed recurrent left-knee pain and mechanical locking after fixation of osteochondritis dissecans of the lateral femoral condyle.

Am J Case RepNov 8, 2026Read case
Clinical ResearchPediatrics

Efficacy of Manual Physiotherapy Techniques for Improving Cervical Range of Motion in Infants With Congenital Muscular Torticollis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed therapist-directed manual physiotherapy techniques for cervical range of motion (ROM) in infants with congenital muscular torticollis.

Physiother Res IntNov 7, 2026Read summary
Clinical ResearchAllergy & Immunology

Pathophysiology Education Using a Pamphlet Among Early School-Age Children With Food Allergies: An Exploratory Pilot Controlled Study.

This non-randomized exploratory pilot controlled study assessed whether individual instruction alongside a pamphlet improved understanding of food allergy pathophysiology in 46 children in grades 1–3 undergoing oral…

Jpn J Nurs SciNov 7, 2026Read summary
Case ReportOncology (Medical)

Progression-Associated Loss of SMARCB1/INI1 Expression in Mismatch Repair-Deficient Glioblastoma.

A patient with mismatch repair-deficient glioblastoma had a recurrent tumor in which testing identified a second SMARCB1 mutation and complete loss of SMARCB1/INI1 protein expression.

Neuropathol Appl NeurobiolNov 7, 2026Read case
Clinical ResearchPsychiatry

Mindfulness-Based Intervention Improves Cognitive Function in Patients With Schizophrenia in Remitted: A Randomized Controlled Trial.

This 8-week, randomized, single-blind controlled trial evaluated mindfulness-based intervention (MBI) in 70 remitted patients with schizophrenia.

Int J Methods Psychiatr ResNov 7, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Relaxivity Performance of Gadopiclenol Versus Gadobenate Dimeglumine In Vitro, and Liver and Brain Imaging: A Randomized Crossover Study.

This randomized intraindividual crossover study compared gadopiclenol with gadobenate dimeglumine in vitro and in liver and brain MRI.

Invest RadiolNov 7, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Prophylactic dexamethasone for prevention of opioid-induced nausea and vomiting in cancer patients: a randomised controlled trial (DEX-OINV Trial).

This open-label randomised controlled trial at a tertiary cancer centre evaluated prophylactic oral dexamethasone in opioid-naïve adults with cancer starting oral morphine.

Support Care CancerNov 7, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Retinal and choroidal changes on optical coherence tomography in pre-eclampsia: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled observational studies comparing OCT measures in women with pre-eclampsia (PE) and control groups.

Int OphthalmolNov 7, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effects of nutrition counseling on quality of life in adults with cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed randomized controlled trials of nutrition counseling and quality of life (QoL) in adults with cancer.

Qual Life ResNov 7, 2026Read summary
Case ReportNeurosurgeryOpen access

Pediatric spontaneous vertebro-venous fistula coil occlusion with vertebral artery preservation and distal vertebral artery flow restoration.

A 9-year-old boy had progressive cervical and upper thoracic pain for 8 months, without neurological deficit. MRI showed a left suboccipital vascular lesion, enlarged bilateral vertebral arteries, and a diminished…

Childs Nerv SystNov 7, 2026Read case
Clinical ResearchOncology (Medical)Open access

Antibiotic Exposure and Treatment Outcomes in Head and Neck Squamous Cell Carcinoma and Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed whether systemic antibiotic exposure around treatment initiation was associated with outcomes in patients with head and neck squamous cell carcinoma or nasopharyngeal…

Curr Oncol RepNov 7, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Vitamin D status and chemotherapy-induced peripheral neuropathy in patients with cancer: a systematic review with exploratory quantitative synthesis.

This systematic review with exploratory quantitative synthesis assessed whether serum or plasma 25-hydroxyvitamin D status was associated with chemotherapy-induced peripheral neuropathy (CIPN) in patients receiving…

Support Care CancerNov 7, 2026Read summary
Case ReportVascular Surgery

Radial Artery Pseudoaneurysm With Individualized Non-Operative Management: A 4-Case Series.

Four patients developed iatrogenic radial artery pseudoaneurysms after arterial access for blood pressure monitoring or coronary angiography. Management was tailored to hand circulation and pseudoaneurysm anatomy.

Am J Case RepNov 7, 2026Read case

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