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1602 articles

October 202624

Clinical ResearchPsychiatryOpen access

Crisis Interventions for Children and Adolescents with Depression and Suicidality: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined crisis services for children and adolescents experiencing acute mental health crises, including severe depression, suicidal ideation, self-harm, and suicidal behaviour.

Curr Psychiatry RepOct 26, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Does the "switch the plane" strategy improve outcomes? Anterior vs. posterior repair for recurrence after prior inguinal hernia repair: a systematic review and meta-analysis.

This systematic review and meta-analysis examined outcomes of recurrent unilateral inguinal hernia repair by operative plane, including comparative studies of posterior versus repeat anterior repair after prior anterior…

HerniaOct 26, 2026Read summary
Case ReportGeneral SurgeryOpen access

Non-recurrent laryngeal nerve with dual branch pattern and merging: a rare anatomical variant encountered during right hemithyroidectomy.

A woman in her 50s underwent right hemithyroidectomy for a benign compressive multinodular goitre. The recurrent laryngeal nerve was not found in its expected tracheo-oesophageal groove position.

Surg Radiol AnatOct 26, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Exposure to antidepressant and antipsychotic medicines in pregnant women and risk of gestational diabetes: a systematic review and meta-analysis of observational studies.

This systematic review and meta-analysis pooled observational studies of gestational diabetes mellitus (GDM) among pregnant women exposed to antidepressants or antipsychotics.

Arch Womens Ment HealthOct 26, 2026Read summary
Clinical ResearchPediatricsOpen access

Adjunctive topical mitomycin C during endoscopic dilation for pediatric caustic esophageal stricture: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis assessed topical mitomycin C (MMC) added to endoscopic dilation for caustic esophageal stricture in children.

Pediatr Surg IntOct 26, 2026Read summary
Case ReportNephrologyOpen access

Oxalate Nephropathy in a patient with Neuroendocrine tumor receiving Long-acting Octreotide.

A 55-year-old man with metastatic somatostatin receptor-positive neuroendocrine tumour received long-acting octreotide and, later, four cycles of 177 Lu-DOTA-TATE peptide receptor radionuclide therapy (PRRT).

CEN Case RepOct 26, 2026Read case
Case ReportNephrologyOpen access

Intracardiac thrombus and multiple venous thromboses revealing focal segmental glomerulosclerosis.

A 51-year-old woman presented with two weeks of lower-limb edema and hematuria. Imaging showed lower-extremity deep vein thrombosis, partial left renal vein thrombosis, and a 23 × 20 mm left ventricular thrombus.

CEN Case RepOct 26, 2026Read case
Clinical ResearchNephrology

Music-based interventions for people with kidney failure undergoing haemodialysis.

This Cochrane systematic review and meta-analysis assessed randomised trials of music-based interventions in people with kidney failure receiving haemodialysis.

Cochrane Database Syst RevOct 26, 2026Read summary
Clinical ResearchPsychiatry

Family Resilience and Coping in Disasters, Pandemics, and Large-Scale Crises: A Systematic Review.

This systematic review synthesized peer-reviewed research on family resilience and coping during disasters, pandemics, and sustained adversity.

Disaster Med Public Health PrepOct 26, 2026Read summary
Case ReportOncology (Medical)

"What a beautiful gift, life": Dignity therapy and the making of a legacy in a patient with grade 4 glioblastoma.

A man in his mid-40s with grade 4 glioblastoma of the corpus callosum received psycho-oncological support from diagnosis, with parallel support for his caregiver.

Palliat Support CareOct 26, 2026Read case
Case ReportOncology (Medical)

Beyond denial: A case report illustrating the complexity of disengagement in advanced cancer care.

A woman in her forties from Africa with advanced metastatic gastric cancer declined prognostic discussions, did not want her family informed, and avoided opioid analgesia.

Palliat Support CareOct 26, 2026Read case
Clinical ResearchPreventive Medicine / Public Health

Are intervention effects on fruit and vegetable intake maintained after 48 months of follow-up? A randomised controlled community trial.

This randomised controlled community trial assessed whether increases in fruit and vegetable (FV) intake after a 7-month transtheoretical model-based intervention were maintained among users of a Brazilian primary…

Public Health NutrOct 26, 2026Read summary
Clinical ResearchNeurology

Impact of age and frailty on the effect of a multimodal individualized long-term intervention after stroke: the last-long trial.

This single-blinded, multicentre randomized controlled trial examined whether age or frailty modified response to a stroke coordinator-led, individualized community intervention.

J Rehabil MedOct 26, 2026Read summary
Case ReportUrology

Bilateral Xanthogranulomatous Pyelonephritis in a Patient With Spina Bifida and Neurogenic Bladder: A Case Report.

A 30-year-old man with spina bifida and neurogenic bladder managed by intermittent catheterization presented with respiratory distress, profound anemia, and declining function.

Am J Case RepOct 26, 2026Read case
Clinical ResearchRadiology (Diagnostic)Open access

A systematic review of the spectrum of magnetic resonance imaging features of degenerative thoracic myelopathy.

This PRISMA-guided systematic review synthesised evidence on MRI features of degenerative thoracic myelopathy (DTM) and their clinical significance.

Neurosurg RevOct 26, 2026Read summary
Clinical ResearchNeurologyOpen access

Dose-Response Effects of Exercise Training on Circulating Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-analysis of Randomised Controlled Trials.

This systematic review and meta-analysis pooled randomised controlled trials comparing chronic exercise with non-exercising controls to assess circulating brain-derived neurotrophic factor (BDNF).

Mol NeurobiolOct 26, 2026Read summary
Case ReportOncology (Medical)

Previously Unrecognized Distinct Laryngeal Lesions During Lazertinib Therapy in EGFR-Mutated NSCLC: A Case Series.

Four patients with non-small cell lung cancer developed new voice changes or a globus sensation while receiving lazertinib-based therapy.

J Korean Med SciOct 26, 2026Read case
Clinical ResearchGastroenterologyOpen access

Gut relief revisited: plecanatide in chronic idiopathic constipation and irritable bowel syndrome with constipation - a systematic review and meta-analysis with GRADE assessment.

This systematic review and meta-analysis with GRADE assessment pooled randomized controlled trials comparing plecanatide with placebo in people with chronic idiopathic constipation (CIC) or irritable bowel syndrome with…

BMC GastroenterolOct 26, 2026Read summary
Clinical ResearchPsychiatry

Lithium in the Prevention of Postpartum Recurrence of Mood Disorders: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed postpartum mood-disorder recurrence among women with bipolar I or II disorder, comparing those who received prophylactic lithium with those who did not.

J Clin PsychiatryOct 26, 2026Read summary
Clinical ResearchCardiology

Individual Effects of Angiotensin II Receptor Blockers on Major Adverse Cardiovascular Events: A Systematic Review and Network Meta-Analysis.

This systematic review and random-effects network meta-analysis compared angiotensin II receptor blockers (ARBs) for cardiovascular outcomes in randomized trials not primarily designed to study heart failure.

Arq Bras CardiolOct 26, 2026Read summary
Clinical ResearchCardiology

Effectiveness of Implantable Cardioverter-Defibrillator Therapy for Primary Prevention in Patients with Nonischemic Heart Failure with Reduced Ejection Fraction.

This rapid systematic review and meta-analysis assessed primary-prevention implantable cardioverter-defibrillator (ICD) therapy in patients with nonischemic heart failure with reduced ejection fraction, drawing on 18…

Arq Bras CardiolOct 26, 2026Read summary
Case ReportAnesthesiologyOpen access

Sequential Lidocaine and Liposomal Bupivacaine for Popliteal Sciatic Nerve Block in Foot and Ankle Surgery: A Randomized Controlled Trial.

In foot and ankle surgery, prolonged analgesia after popliteal sciatic nerve block (PSNB) may be accompanied by delayed motor recovery.

Drug Des Devel TherOct 26, 2026Read case
Clinical ResearchOrthopedic Surgery

Clinical Pathway Management for Platelet-Rich Plasma Therapy in Kellgren-Lawrence Grade I and II Knee Osteoarthritis: A Prospective, Multicenter, Double-Blind Randomized Controlled Trial.

This multicenter, double-blind randomized controlled trial compared a standardized platelet-rich plasma (PRP) pathway with physician-directed conventional PRP care in patients with Kellgren-Lawrence grade I or II knee…

Am J Sports MedOct 26, 2026Read summary
Clinical ResearchOncology (Medical)

Ruzaltatug rezetecan versus chemotherapy for EGFR-mutated advanced non-small-cell lung cancer progressing after EGFR tyrosine kinase inhibitor therapy (HERON-Lung01): interim analysis of a randomised, open-label, phase 3 trial in China.

HERON-Lung01 was a randomised, open-label, phase 3 trial at 62 sites in China comparing the HER3-directed antibody-drug conjugate ruzaltatug rezetecan with platinum-pemetrexed chemotherapy in patients with EGFR-mutated…

LancetOct 26, 2026Read summary

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