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1602 articles

October 202624

Clinical ResearchVascular SurgeryOpen access

Revascularization of Asymptomatic Carotid Artery Stenosis: Cognitive Results of the CREST-2 Randomized Trials.

This prespecified cognitive-outcomes analysis of the multicentre, randomised CREST-2 trials assessed patients aged 35 years or older with at least 70% asymptomatic carotid stenosis.

JAMAOct 27, 2026Read summary
Clinical ResearchVascular SurgeryOpen access

Revascularization in Asymptomatic Carotid Artery Stenosis With Hemodynamic Impairment and Cognitive Outcomes: The CREST-H Substudy of the CREST-2 Randomized Clinical Trial.

This multicenter substudy of a phase 3 randomized clinical trial examined whether baseline cerebral hemodynamic impairment modified cognitive outcomes after carotid revascularization in adults with high-grade…

JAMAOct 27, 2026Read summary
Case ReportDermatology

Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.

A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.

Clin Exp DermatolOct 27, 2026Read case
Case ReportDermatology

Cutaneous features of SDR9C7 variants in eight individuals with autosomal recessive nonsyndromic epidermal differentiation disorders.

Eight individuals with SDR9C7 variants and nonsyndromic epidermal differentiation disorders had scaling and erythema, commonly with fine scale, hyperlinear palms, and greater involvement of the extremities, particularly…

Clin Exp DermatolOct 27, 2026Read case
Clinical ResearchDermatology

The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.

This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.

Clin Exp DermatolOct 27, 2026Read summary
Clinical ResearchDermatology

Efficacy and safety of icotrokinra for plaque psoriasis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed icotrokinra, an oral IL-23 receptor antagonist, in adolescents and adults with moderate-to-severe plaque psoriasis.

Clin Exp DermatolOct 27, 2026Read summary
Clinical ResearchPediatrics

Efficacy and safety of Lianhua Qingwen versus oseltamivir in children with influenza: a multicenter, randomized, double-blind, positive parallel-controlled study.

This multicenter, randomized, double-blind, positive-controlled trial compared Lianhua Qingwen (LHQW) with oseltamivir in children aged 3–14 years with influenza.

Pharm BiolOct 27, 2026Read summary
Clinical ResearchEmergency Medicine

Diagnostic accuracy of high-sensitivity point-of-care troponin assays in emergency department for patients presenting with chest pain: a systematic review.

This systematic review assessed the diagnostic accuracy of four commercially available high-sensitivity point-of-care troponin assays in adults presenting to emergency departments with chest pain suggestive of acute…

Eur J Emerg MedOct 27, 2026Read summary
Clinical ResearchNeurosurgery

Intra-wound Vancomycin Powder for Surgical Site Infection Prophylaxis in Spinal Surgery: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis examined intra-wound vancomycin powder at closure versus no powder in patients undergoing spinal surgery.

J Vis ExpOct 27, 2026Read summary
Case ReportPhysical Medicine & Rehabilitation

Ultrasound-Guided High-Voltage Long-Duration Pulsed Radiofrequency of the Suprascapular Nerve for Persistent Hemiplegic Shoulder Pain.

The report describes two patients with persistent hemiplegic shoulder pain after stroke, in whom conventional conservative care or suprascapular nerve blocks may provide inadequate relief.

J Vis ExpOct 27, 2026Read case
Case ReportGeneral SurgeryOpen access

Novel Fluorescence-Guided Gastric Calibration Tube in Robotic Paraesophageal Hernia Repair.

A 75-year-old woman with symptomatic paraesophageal hiatal hernia and partial gastric volvulus underwent robotic hernia repair with Toupet fundoplication.

CRSLSOct 27, 2026Read case
Case ReportPediatricsOpen access

Reconstructive management of an extensive myelomeningocele defect using allogeneic fascia lata as temporary biological coverage: a case-based mini-review.

A term male newborn had a 16 × 10 cm thoracolumbosacral myelomeningocele with too little surrounding skin for tension-free primary closure.

Childs Nerv SystOct 27, 2026Read case
Clinical ResearchFamily Medicine

An mHealth Stress Management Intervention for Latino Millennial Caregivers: Pilot Feasibility Randomized Controlled Trial.

This pilot feasibility randomized controlled trial evaluated a culturally tailored, automated mobile intervention for stress management and emotional regulation among Latino millennial caregivers in the United States.

JMIR Form ResOct 27, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing.

This randomized controlled trial tested whether personalizing cognitive remediation (CR) by baseline early auditory processing (EAP) status improved outcomes in 184 outpatient adults with schizophrenia.

Schizophr BullOct 27, 2026Read summary
Clinical ResearchPulmonologyOpen access

Comparative Effects of Different Mind-Body Exercises on Lung Function, Exercise Capacity, and Quality of Life in Adults with Stable Chronic Obstructive Pulmonary Disease: A Bayesian Network Meta-Analysis.

This Bayesian network meta-analysis assessed mind-body exercises (MBEs) for lung function, exercise capacity, and quality of life in adults with stable COPD.

Int J Chron Obstruct Pulmon DisOct 27, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Effect of Preoperative Intranasal Dexmedetomidine on Postoperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting.

To evaluate the effects of preoperative intranasal dexmedetomidine on postoperative myocardial injury biomarkers in patients undergoing on-pump coronary artery bypass grafting (CABG).

Drug Des Devel TherOct 27, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effect of Adding Esketamine to Patient-Controlled Intravenous Analgesia on Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether adding esketamine to postoperative patient-controlled intravenous analgesia (PCIA) reduces rebound pain after interscalene brachial plexus block in patients undergoing…

Drug Des Devel TherOct 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Long-term gynecological symptoms and ultrasound and reproductive outcomes after monofilament vs multifilament uterine closure at Cesarean delivery: secondary analysis of randomized controlled trial.

This secondary analysis of a randomized controlled trial compared long-term outcomes after monofilament versus multifilament absorbable uterine closure at Cesarean delivery.

Ultrasound Obstet GynecolOct 27, 2026Read summary
Clinical ResearchPsychiatry

Psychedelics and psychosis: A systematic review of recent-era studies (1984-2025).

This systematic review examined evidence from 1984–2025 on classical psychedelic use and psychotic symptoms, drawing on 52 papers, including population studies, clinical trials, emergency and toxicology data, and case…

J PsychopharmacolOct 27, 2026Read summary
Clinical ResearchOncology (Medical)

Antibiotics and outcomes of cancer immunotherapy: An updated meta-analysis and clinical applications.

This updated meta-analysis examined antibiotic exposure and outcomes among 97,850 patients with cancer treated with immune checkpoint inhibitors (ICI), drawing on 116 cohorts.

Cancer CellOct 27, 2026Read summary
Clinical ResearchInfectious Diseases

Hemagglutinin- and neuraminidase-targeting antibody responses after receipt of egg-based inactivated or recombinant influenza vaccines among adults aged 18-64 years.

This randomized trial compared hemagglutinin (HA)- and neuraminidase (NA)-targeting antibody responses after 2022–2023 recombinant influenza vaccine (RIV) or standard-dose inactivated influenza vaccine (SD-IIV) in…

VaccineOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Exposure to natural disasters and vaccination indicators: a systematic review and directions for future research.

This systematic review examined peer-reviewed research on exposure to natural disasters and vaccination indicators, including vaccine administration, coverage, and rates.

VaccineOct 27, 2026Read summary
Clinical ResearchPsychiatry

Measurement properties of anhedonia-related patient-reported outcome measures in depression-related populations: A COSMIN systematic review.

This COSMIN systematic review evaluated the measurement properties of anhedonia-related patient-reported outcome measures in depression-related populations.

J Affect DisordOct 27, 2026Read summary
Clinical ResearchPsychiatry

Hippocampal subfield functional connectivity alterations in major depressive disorder: A systematic review and meta-analysis.

This systematic review and meta-analysis examined functional connectivity (FC) involving hippocampal subfields or subregions in major depressive disorder (MDD), comparing findings with healthy controls and summarizing…

J Affect DisordOct 27, 2026Read summary

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