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2000 articles
November 202624
The characteristics of men who have sex with men presenting with oral syphilis: a systematic review.
This systematic review described demographic, behavioural, co-infection and clinical features of men who have sex with men (MSM) presenting with oral syphilis.
Intractable Nausea and Vomiting: A Key Feature of Neuromyelitis Optica Spectrum Disorder.
A 22-year-old woman had five weeks of intractable nausea, vomiting, and hiccups. Delayed gastric emptying led to an initial diagnosis of gastroparesis, but symptoms persisted despite antiemetic and prokinetic therapy.
Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): a randomized controlled trial.
This multicentre randomized controlled trial tested whether app-based cognitive behavioural therapy (CBT) reduced persistent postsurgical pain in adults with operatively treated extremity fractures at 11 hospitals in…
Sex Differences in Blood Pressure Dynamics and Outcomes After Endovascular Thrombectomy.
This exploratory secondary analysis of the multicenter, open-label, blinded-end-point ENCHANTED2/MT randomized trial examined sex differences in blood pressure (BP) and outcomes among adults with acute ischemic stroke…
Single-port robotic thoracic surgery: a systematic review and meta-analysis of comparative outcomes versus multiport robotic surgery and uniportal VATS.
This systematic review and meta-analysis compared single-port robotic-assisted thoracic surgery (SP-RATS) with multiport robotic surgery (MP-RATS) and uniportal video-assisted thoracoscopic surgery (uVATS).
Barriers and facilitators to HPV vaccination among adult men: A systematic review and qualitative meta-synthesis.
This qualitative systematic review and meta-synthesis examined barriers and facilitators to HPV vaccination among adult men and how healthcare services address vaccination needs.
Pearls & Oy-sters: Anti-GABA A Receptor Encephalitis Presenting as Fulminant Hemicerebellitis in a 5-Year-Old Girl.
A previously healthy 5-year-old girl developed acute neurologic decline after several days of fever and malaise. CT showed severe right cerebellar inflammation and edema with fourth-ventricle effacement, prompting…
Dose-specific effects of caffeinated chewing gum on reactive blocking timing, jump mechanics, and neuromuscular responses after volleyball-specific fatigue in elite female volleyball players.
This randomized, double-blind, placebo-controlled crossover study examined caffeinated chewing gum in 15 elite female volleyball players after a volleyball-specific repeated-blocking fatigue protocol.
Prolonged exposure, eye movement desensitization and reprocessing therapy, and cognitive restructuring versus waiting-list for individuals with PTSD and psychosis (RE.PROCESS): A multicenter, four-arm, assessor-masked, superiority randomized controlled trial.
The multicenter, assessor-masked RE.PROCESS randomized controlled trial compared Prolonged Exposure (PE), eye movement desensitization and reprocessing (EMDR), and Cognitive Restructuring (CR), each alongside usual…
Prevalence and Consequences of Guideline-Directed Indications for Aortic Valve Replacement in the EARLY TAVR Trial.
This analysis of the multicenter randomized EARLY TAVR trial examined how often patients with asymptomatic severe aortic stenosis had ACC/AHA Class II indications for aortic valve replacement (AVR), and whether these…
Altered effective connectivity during cognitive distancing in cognitive behavioral therapy nonresponders with depression.
This clinical trial analysis examined whether pretreatment brain connectivity during cognitive distancing was associated with cognitive behavioral therapy (CBT) response in 77 outpatients with major depressive disorder.
Clinical Reasoning: A 69-Year-Old Female Patient With Rapid-Onset Levodopa-Responsive Rest Tremor, Parkinsonism, and Gait Freezing.
A 69-year-old woman developed a unilateral resting tremor that rapidly spread to the opposite arm and then the legs. Within 3 months, she had generalized parkinsonism, a shuffling gait with prominent freezing, and…
Efficacy and safety of the cladribine, idarubicin, and cytarabine regimen for treating acute myeloid leukemia: a systematic review and single-arm meta-analysis.
This systematic review and single-arm meta-analysis assessed the efficacy and safety of cladribine, idarubicin, and cytarabine (CIA) for acute myeloid leukemia (AML), separating newly diagnosed (ND) from…
Short-term outcomes of the hinotori versus da Vinci robotic surgical systems in colorectal cancer surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis compared short-term perioperative outcomes of hinotori and da Vinci robotic systems in colorectal cancer surgery.
Cardiac Damage and Clinical Outcomes in Symptomatic Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
This post hoc subanalysis of the multicentre, randomised LANDMARK trial examined whether updated echocardiographic cardiac-damage stages stratified outcomes after transcatheter aortic valve replacement (TAVR) in…
Evening amber-lensed glasses in combination with a prescribed wake time advance circadian timing in adolescents with delayed sleep-wake phase disorder.
This 3-week randomized controlled trial tested evening amber-lensed glasses plus a prescribed stable wake time in adolescents aged 14.3–18.1 years with delayed sleep-wake phase disorder (DSWPD).
Surgical outcomes and functional morbidity after retrosigmoid/retrocondylar and midline suboccipital approaches for foramen magnum meningiomas: a single-arm meta-analysis.
This PRISMA-guided systematic review and single-arm meta-analysis assessed surgical control and functional morbidity after posterior or posterolateral approaches for foramen magnum meningiomas.
Multiorgan [ 18 F]florbetapir PET/CT uptake in multiple myeloma-associated systemic AL amyloidosis: a case report.
A 77-year-old man with multiple myeloma underwent whole-body [18F]florbetapir PET/CT because AL amyloidosis was suspected. The scan showed prominent tracer retention in the myocardium, thyroid, lungs, parotid glands…
Pertuzumab in HER2-positive breast cancer: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled 8 randomized controlled trials involving 8367 patients with HER2-positive breast cancer to assess pertuzumab-based regimens.
Sequencing trastuzumab deruxtecan and sacituzumab govitecan in metastatic breast cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether treatment order affects outcomes when patients with metastatic breast cancer receive both trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG).
Operative versus nonoperative management of olecranon fractures in older adults: a systematic review and meta-analysis.
This systematic review and meta-analysis compared operative with nonoperative management of displaced olecranon fractures in older adults.
Association of HTR3A and COMT polymorphisms with electroacupuncture response for chemotherapy-induced nausea and vomiting in breast cancer: a secondary analysis of a randomized controlled trial.
This exploratory, treatment-stratified secondary analysis of a randomized controlled trial examined whether three HTR3A and COMT polymorphisms were associated with complete protection (CP) against chemotherapy-induced…
Impact of artificial intelligence-assisted health management on blood pressure and self-management efficacy in older adults with hypertension.
This randomized controlled trial compared AI-assisted health management with routine care in older adults with hypertension. The intervention included intelligent monitoring, early warning and proactive intervention.
Machine Learning Models for Glycemic Prediction in Type 1 and Type 2 Diabetes: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed machine-learning models predicting glucose values or glycemic events in people with type 1, type 2, mixed, or unclear diabetes.
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