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2000 articles
November 202624
Physiological prehabilitation for patients undergoing cellular therapy in multiple myeloma and lymphoma: a systematic review.
This systematic review examined exercise-based physiological prehabilitation in adults with multiple myeloma or lymphoma before cellular or immune-based therapy.
Fetal myelomeningocele repair: Rome Fondazione Policlinico A. Gemelli IRCCS experience.
A fetus with distal lumbar myelomeningocele was assessed by fetal MRI, which showed a 23 × 11-mm defect, ventricular dilatation, and Chiari II malformation. Open fetal repair was performed at 25 weeks of gestation.
Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.
Robotic pancreatic enucleation versus laparoscopic pancreatic enucleation: a meta-analysis.
This meta-analysis compared robotic with laparoscopic pancreatic enucleation for perioperative outcomes. It pooled five cohort studies involving 272 patients (128 robotic and 144 laparoscopic).
Changes in self-related cognitive processes and depressive symptom severity following a single, moderate dose of psilocybin in depressed patients.
This randomized, double-blind, placebo-controlled trial examined depressive symptoms, self-concept and neural markers of self-referential processing in 37 people with major depressive disorder.
What Cochlear Implantation with Attempted Hearing Preservation in Widened Vestibular Aqueduct Adds to Understanding About the Etiology and Pathogenesis of Hearing Loss: A Systematic Review.
This PRISMA-compliant systematic review examined hearing preservation cochlear implantation in children with widened vestibular aqueduct (WVA), a congenital inner-ear malformation associated with childhood sensorineural…
Combined Immunotherapy and Hybrid Dose-Fraction Radiotherapy for Driver-Negative Metastatic NSCLC: A Phase II Trial with Parallel Preclinical Studies.
This single-arm, multicenter phase II trial evaluated hybrid dose-fraction radiotherapy added during first-line chemoimmunotherapy maintenance in 83 patients with stage IV driver-negative metastatic NSCLC.
Hyoid Bone Fracture in a Patient as a Rare Cause of Persistent Postoperative Dysphagia Following Anterior Cervical Discectomy and Fusion.
A 76-year-old woman developed severe, persistent dysphagia and progressive odynophagia after C3–5 anterior cervical discectomy and fusion.
Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.
This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.
A flap with its own blood supply: robot-assisted appendiceal ureteroplasty for complex ureteral strictures-a systematic review and single-arm meta-analysis.
This systematic review and single-arm proportional meta-analysis assessed the success and safety of robot-assisted appendiceal ureteroplasty (RAU) for complex upper- and mid-ureteral strictures in adults.
Effectiveness of guided internet-delivered cognitive behavioral therapy for insomnia in autistic adults (i-Sleep Autism): a randomized controlled trial.
This randomized controlled trial evaluated a 5-week, guided internet-delivered cognitive behavioral therapy intervention adapted for autistic adults with insomnia.
Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.
This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…
Multidisciplinary management of disseminated tuberculosis with tuberculous meningitis and active hepatitis B in a critically ill pregnant woman in the third trimester: a case report.
A 24-year-old woman at 30 weeks’ gestation presented with headache, vomiting, fever, and nuchal rigidity. Cerebrospinal fluid findings confirmed tuberculous meningitis, and chest CT showed diffuse miliary nodules…
Arterial-to-End-Tidal CO₂ Gradient Direction as a Differential Diagnostic Clue During Sudden Hypercapnia in Thoracoscopic Surgery with Capnothorax: A Report of 2 Cases.
Two men undergoing thoracoscopic surgery with CO₂ insufflation developed abrupt rises in end-tidal CO₂ (EtCO₂). In the first, the rise coincided with severe hypotension and bradycardia; arterial blood gas showed PaCO₂…
Comparative Efficacy of Different Biologic Agents on Radiographic Progression in Patients with Rheumatoid Arthritis: A Network Meta-Analysis.
This Bayesian random-effects network meta-analysis compared six biologic DMARD classes for radiographic progression in rheumatoid arthritis, using randomized controlled trials and change in modified Total Sharp Score…
Feasibility of robotic-assisted surgery for nutcracker syndrome: a systematic review and single-arm meta-analysis.
This systematic review and single-arm meta-analysis assessed robotic-assisted surgery for nutcracker syndrome (NCS), using 10 studies of 140 patients, mostly retrospective case series.
Spatial transcriptomics tumor microenvironment determinants of tyrosine kinase inhibitor response in renal cell carcinoma: results from a phase 2 clinical trial.
This phase 2 clinical trial examined whether spatially resolved tumor gene-expression patterns were associated with sunitinib response in 46 patients with metastatic clear cell renal cell carcinoma.
Diagnostic yield and early outcomes of radical prostatectomy without prior histopathologic diagnosis: a single-arm systematic review and meta-analysis.
This single-arm systematic review and random-effects meta-analysis assessed radical prostatectomy without prior histopathologic confirmation in adult men with high clinical suspicion of clinically significant prostate…
Comparison of alignment in patients with buccally displaced maxillary canines using T-loop mechanics and continuous arch mechanics: a randomized clinical trial.
This parallel, two-arm randomized clinical trial compared T-loop mechanics (TLM) with continuous arch mechanics (CAM) for aligning maxillary anterior teeth in 26 patients with unilateral or bilateral buccally displaced…
Outcomes with Catheter-Directed Thrombolysis versus Mechanical Thrombectomy for Patients with Intermediate/High Risk Pulmonary Embolism: A Meta-Analysis of 24,090 Patients.
This meta-analysis compared catheter-directed thrombolysis (CDT) with mechanical thrombectomy (MT) in patients with intermediate- or high-risk pulmonary embolism treated with catheter-based therapies.
Acupuncture after surgery of soft tissue tumors of the extremities: postoperative pain and feasibility: a prospective trial.
This prospective, single-arm, single-centre pilot study assessed acupuncture feasibility and postoperative pain after extremity soft tissue tumor resection in 25 patients.
Impact of nasogastric administration using the simple suspension method on serum tirabrutinib levels: A case report.
An 82-year-old man with relapsed primary central nervous system lymphoma began tirabrutinib at 320 mg/day while fasting. As dysphagia progressed, administration changed from swallowing tablets to nasogastric delivery by…
Acute doses of 3 and 6 mg/kg caffeine produce outcome- and phase-specific improvements in male 100-m sprinters: A randomized, double-blind, placebo-controlled crossover trial.
This randomized, double-blind, placebo-controlled crossover trial tested acute caffeine doses in 21 male 100-m sprinters. After placebo, 3 mg/kg, or 6 mg/kg, participants completed sprint and other performance tests.
Left bundle branch area vs biventricular pacing for cardiac resynchronization therapy: the LEFT-BUNDLE-CRT trial.
The multicentre, randomized, non-inferiority LEFT-BUNDLE-CRT trial compared left-bundle branch area pacing (LBBAP) with biventricular pacing (BiVP) for cardiac resynchronization in patients with guideline-based…
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