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2000 articles
October 202624
A 61-Year-Old Woman With Locally Advanced Pancreatic Adenocarcinoma Managed With Neoadjuvant FOLFIRINOX, Total Pancreatectomy, Splenectomy, Portal Vein and Common Hepatic Artery Resection, and Combined Vascular Reconstruction Using Splenic Artery Transposition: A Case Report.
A 61-year-old woman presented with progressive jaundice and CA 19-9 of 210 U/mL. Biopsy confirmed pancreatic ductal adenocarcinoma, and imaging showed portal vein and common hepatic artery involvement without distant…
An intervention based on acceptance and commitment therapy for people experiencing work- or career-related difficulties: A randomized controlled trial.
This randomized controlled trial evaluated a seven-session online group intervention based on acceptance and commitment therapy among people experiencing work- or career-related difficulties, including job loss and…
Curative-intent management of de novo metastatic nasopharyngeal carcinoma: an evidence-based consensus guideline from the International Collaborating Oncology Organisations.
This international consensus guideline addresses curative-intent management of de novo metastatic nasopharyngeal carcinoma, a population historically treated with palliative intent.
AI-facilitated individualized nutritional guidance with ABC-structured prompts improves short-term dietary intake adequacy and patient-reported symptoms after gastrointestinal cancer surgery: a randomized controlled trial.
This single-center randomized controlled trial compared AI-facilitated, individualized and quantified dietary guidance plus clinician review with standard discharge advice in 90 patients after laparoscopic gastric or…
Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials.
This systematic review and individual participant data meta-analysis combined five randomised trials comparing 0/1 h with 0/3 h cardiac troponin pathways in patients presenting with suspected myocardial infarction.
Multiple Organ Failure Secondary to Pancreatitis Due to Biliary Ascariasis in a Young Patient: A Case Report on the Importance of a Good Anamnesis.
A 22-year-old man from rural Honduras presented in refractory shock with encephalopathy, jaundice, gastrointestinal bleeding, severe hepatic dysfunction, acute kidney injury, and rhabdomyolysis after taking large…
Artificial intelligence-enabled interventions for smoking cessation: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis assessed randomised controlled trials of AI-enabled smoking-cessation interventions in adults who smoked combustible cigarettes.
Expected change: a new concept for monitoring patients on oral bisphosphonates.
This randomized controlled trial evaluated ways to monitor response to oral bisphosphonates in 108 postmenopausal women younger than 85 years treated with alendronate, ibandronate, or risedronate, with calcium and…
BCMA-directed CAR T-cell therapy induces durable drug-free remission in refractory primary immune thrombocytopenia.
This phase I clinical trial evaluated B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T-cell therapy in 4 patients with refractory primary immune thrombocytopenia.
What are the palliative and end-of-life care needs and preferences of people with cancer from culturally and linguistically diverse (CALD) backgrounds?: A systematic review.
This systematic review synthesised evidence on palliative and end-of-life care needs and preferences among people with cancer from culturally and linguistically diverse (CALD) backgrounds, and on factors affecting…
The Effect of Using Heated IV Fluids With Underbody Warmers on Maternal and Neonatal Well-Being in Cesarean Delivery Operations: A Randomized Clinical Trial.
This randomized clinical trial at a university hospital compared underbody warming alone, underbody warming plus heated IV fluids, and passive blanket heating in 105 pregnant patients undergoing cesarean delivery.
A pilot study of electromagnetic therapy versus biofeedback-based pelvic floor muscle training for pelvic organ prolapse: A mixed-methods approach.
This mixed-methods pilot randomised trial compared high-intensity focused electromagnetic (HIFEM) therapy, supervised pelvic floor muscle training (PFMT) with biofeedback and/or electrostimulation, and usual care in…
Effectiveness of a Ceramide-Based Lamellar Emulsion on Skin Barrier Function in Surgical Nurses: A Randomized Controlled Trial.
This single-center randomized controlled trial assessed whether a ceramide-based lamellar emulsion improved hand skin barrier function in surgical nurses exposed to frequent perioperative hand hygiene.
A Systematic Review and Meta-Analysis of Randomized Clinical Trials Comparing the Effectiveness of Corticosteroid Injection Versus Night Splints in Patients With Carpal Tunnel Syndrome.
This systematic review and meta-analysis of randomized controlled trials compared corticosteroid injection (CSI) with night splinting (NS) for carpal tunnel syndrome.
Vertebral fractures in a young woman: the impact of hypogonadism, glucocorticoids, and chronic disease.
A premenopausal woman developed painful vertebral fractures while receiving prednisolone for newly diagnosed systemic lupus erythematosus.
Maternity versus non-maternity healthcare settings for the diagnosis of gestational diabetes or diabetes in pregnancy.
This Cochrane systematic review and meta-analysis assessed whether maternity or non-maternity healthcare settings affect screening and diagnosis of gestational diabetes or diabetes in pregnancy.
Human milk oligosaccharide (2'-FL) modifies the gut microbiome in children after bone marrow transplant.
This prospective phase 1/2 clinical trial evaluated daily oral 2′-fucosyllactose (2′-FL), a human milk oligosaccharide, from conditioning through day +30 in children undergoing allogeneic hematopoietic stem cell…
Infantile posterior fossa atypical teratoid/rhabdoid tumor: navigating diagnostic complexity and molecular paradigms.
A female infant younger than 1 year presented with a massive cystic-solid posterior fossa tumor and rapidly developing obstructive hydrocephalus.
Levodopa or dopamine agonists for enhancing motor function after stroke.
This Cochrane systematic review and meta-analysis assessed whether levodopa or dopamine agonists improve motor function after stroke.
Efficacy of High-Frequency Transcranial Magnetic Stimulation Therapy for Depression With Insomnia Symptoms: A Systematic Review and Meta-Analysis Based on Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials assessed left dorsolateral prefrontal cortex-targeted high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for people with…
The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.
Effects of Walnut Consumption on Inflammatory Cytokines and Adipokines in Adults: A Systematic Review and Dose-Response Meta-Analysis.
This systematic review and dose-response meta-analysis assessed randomized trials of walnut intake and inflammatory cytokines and adipokines in adults.
A rare cause of postpartum hemoperitoneum: Uterine laceration secondary to sustained transabdominal uterine massage following vaginal delivery: A case report.
After vaginal delivery, a patient with an unscarred uterus developed postpartum hemorrhage from uterine atony and was treated with uterotonics and transabdominal uterine massage.
PIH1D2 Loss-of-Function Directs Ciliary and Cell Cycle Defects Resulting in Left Isomerism With or Without Biliary Atresia.
Two unrelated patients with left isomerism heterotaxy were found by genome sequencing to have biallelic loss-of-function variants in PIH1D2.
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