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2000 articles

November 202624

Clinical ResearchRadiology (Diagnostic)

Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed imaging methods for visualizing deep cerebral perforating arteries in human studies.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchNeurologyOpen access

Tenecteplase Before Thrombectomy at 4.5 to 24 Hours for Basilar Artery Occlusion: The ATTENTION LATE Randomized Clinical Trial.

This multicenter, open-label, blinded-endpoint randomized clinical trial compared intravenous tenecteplase before endovascular thrombectomy (EVT) with EVT alone in patients with moderate to severe basilar artery…

JAMANov 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Adjuvant mFOLFOXIRI after curative-intent resection of oligometastatic colorectal cancer: phase II FANTASTIC trial.

The multicentre, non-randomized phase II FANTASTIC trial evaluated adjuvant modified FOLFOXIRI after complete metastasectomy for oligometastatic colorectal cancer and assessed circulating tumour DNA (ctDNA).

BJS OpenNov 3, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of Lumateperone 42 mg in Major Depressive Disorder: Subgroup Analysis of a Phase 3 Randomized, Placebo-Controlled Trial.

This post hoc subgroup analysis of a phase 3, randomized, double-blind, placebo-controlled trial assessed adjunctive lumateperone 42 mg in adults with major depressive disorder and inadequate response to antidepressant…

Prim Care Companion CNS DisordNov 3, 2026Read summary
Clinical ResearchPediatrics

Pain, sensory acceptability, and treatment compliance following cryotherapy and topical anesthetics in children: A randomized clinical trial.

This randomized clinical trial compared cryotherapy with topical anesthetics in 100 healthy children aged 7–10 years receiving their first dental treatment.

PLoS OneNov 3, 2026Read summary
Clinical ResearchHematology

TIM3 Blockade with Hypomethylating Therapy Restores NK Cell and Cytotoxic CD4+ T-cell Activity in Patients with AML or MDS.

This phase Ib clinical trial examined immune changes in patients with AML or MDS treated with anti-TIM3 sabatolimab plus decitabine.

Cancer Immunol ResNov 3, 2026Read summary
Case ReportRheumatologyOpen access

Pulmonary-Cardiac Involvement in a Patient with IgA Vasculitis.

A 41-year-old woman with biopsy-proven IgA nephropathy presented with progressive dyspnea, hemoptysis, and a painful purpuric rash.

Methodist Debakey Cardiovasc JNov 3, 2026Read case
Case ReportMedical GeneticsOpen access

KARS1-Related Infantile-Onset Progressive Leukoencephalopathy With or Without Deafness: A Novel Variant and Phenotypic Expansion.

A two-year-old Iranian boy born to non-consanguineous parents presented with developmental delay, seizures, and sensorineural hearing loss.

J Mol NeurosciNov 3, 2026Read case
Case ReportDermatology

A Case of Facial Alternaria alternata Infection in an Immunocompetent Male with Albinism.

A 26-year-old immunocompetent man with albinism who worked in breeding presented with a two-month history of itchy facial rashes.

MycopathologiaNov 3, 2026Read case
Clinical ResearchRadiology (Diagnostic)Open access

Radiomics performance to identify high-risk carotid artery plaques: a systematic review.

This systematic review assessed radiomics-based models for identifying high-risk carotid plaques. It included 28 studies involving 6,108 patients, 72.4% of whom were male.

Eur Radiol ExpNov 3, 2026Read summary
Clinical ResearchOrthopedic Surgery

Comparative Effectiveness of Non-Pharmacological Interventions for Management of Post-Orthodontic Pain: A Systematic Review and Network Meta-Analysis.

This systematic review and Bayesian network meta-analysis compared nine non-pharmacological approaches for orthodontic pain after fixed-appliance activation.

J Vis ExpNov 3, 2026Read summary
Clinical ResearchPulmonology

Transbronchial Cryobiopsy for the Diagnosis of Peripheral Pulmonary Lesions: A Prospective Randomized Controlled Study.

This prospective, single-center randomized controlled study compared radial endobronchial ultrasound with guide-sheath-assisted transbronchial cryobiopsy (TBCB) using a 1.1-mm ultrathin probe with conventional forceps…

J Vis ExpNov 3, 2026Read summary
Case ReportInfectious Diseases

Short communication: Urinary schistosomiasis mimicking a bladder tumour in a Somali student diagnosed in Türkiye.

A 20-year-old Somali student living in Türkiye presented with painless visible haematuria and lower urinary tract symptoms. He had a history of freshwater exposure in Somalia.

J HelmintholNov 3, 2026Read case
Case ReportOncology (Medical)Open access

Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.

A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.

Childs Nerv SystNov 3, 2026Read case
Clinical ResearchCardiothoracic Surgery

Multivessel Versus Single-Vessel Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Meta-Analysis of Short-Term Outcomes and Implications for Target-Vessel Selection.

This meta-analysis compared short-term outcomes after single-vessel versus multivessel coronary endarterectomy (CE) performed with coronary artery bypass grafting (CABG), using studies that reported both groups within…

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read summary
Case ReportNeurologyOpen access

Network-Based Deep Brain Stimulation Rescue After Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor: Two Targeting Strategies.

Two men developed recurrent essential tremor after MRgFUS thalamotomy. In the 71-year-old, DBS was placed along a Vim–posterior subthalamic area trajectory.

Tremor Other Hyperkinet Mov (N Y)Nov 3, 2026Read case
Clinical ResearchOncology (Medical)Open access

Effectiveness of home-based exercise interventions on cardiorespiratory fitness and cancer treatment-related cardiovascular toxicity in cancer survivors exposed to cardiotoxic therapies: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis of randomized controlled trials assessed structured home-based exercise in cancer survivors exposed to cardiotoxic therapies. Ten trials involving 851 participants were included.

Support Care CancerNov 3, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Epidemiological, etiological, and antifungal resistance patterns of vulvovaginal Candida spp. infections in Cameroon: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled evidence from 34 studies of vulvovaginal Candida infection and vulvovaginal candidiasis (VVC) in Cameroon.

Med MycolNov 3, 2026Read summary
Case ReportGastroenterology

Submucosal Tunnel Endoscopic Resection of a Gastric Schwannoma Mimicking a Submucosal Tumor.

A 73-year-old woman with recurrent abdominal distension was found on esophagogastroduodenoscopy to have an 8.2 mm submucosal lesion in the gastric body.

J Vis ExpNov 3, 2026Read case
Clinical ResearchGastroenterology

Rifamycin use and gut microbial antibiotic resistance genes in cirrhosis: Results from a double-blind, placebo-controlled clinical trial.

This double-blind, placebo-controlled randomized trial assessed changes in gut antimicrobial resistance genes (ARGs) with rifamycin SV MMX (RiVM) in patients with compensated cirrhosis.

Gut MicrobesNov 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Oncologic efficacy and safety of stereotactic body radiotherapy for oligometastatic non-small cell lung cancer: a systemic meta-analysis.

This systematic review and meta-analysis assessed the efficacy and safety of stereotactic body radiotherapy (SBRT) for oligometastatic non-small cell lung cancer, including analyses by oligometastatic subtype and…

Clin Exp MetastasisNov 3, 2026Read summary
Case ReportPediatricsOpen access

Shotgun metagenomic characterization of human adenovirus F40 and a non-cpe Clostridium perfringens strain in pediatric prolonged diarrhea: a genome-resolved case study.

A child with prolonged diarrhea had adenovirus identified as the sole pathogen by routine testing. Shotgun metagenomic sequencing of stool confirmed human adenovirus F40 (HAdV-F40), phylogenetically distinct from…

BMC Infect DisNov 3, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Robotic-assisted total knee arthroplasty demonstrates superior early functional outcomes compared with conventional total knee arthroplasty: a quasi-randomised controlled trial.

This quasi-randomised controlled trial compared 1-year outcomes after primary total knee arthroplasty (TKA) in 845 patients treated with robotic-assisted or conventional workflows at one institution.

J Orthop TraumatolNov 3, 2026Read summary
Case ReportPsychiatry

Catatonic signs during delirium in leptomeningeal melanoma: Treatment trade-offs in end-of-life care.

A man in his late 30s with metastatic melanoma involving the leptomeninges and brain developed fluctuating arousal, inattention, disorientation, mutism, immobility, staring, withdrawal, and waxy flexibility.

Palliat Support CareNov 3, 2026Read case

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