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1357 articles
November 202624
Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.
This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.
The Role of Diet and Physical Activity in Gut Microbiota Modulation in Type 2 Diabetes Management: A Systematic Review of Clinical Trials.
This systematic review assessed clinical trials of dietary and physical activity interventions and gut microbiota in adults with type 2 diabetes or prediabetes.
Current Evidence of Digital and Hand Replantation Following Cold Ischemia or Cryopreservation: A Systematic Review.
This systematic review examined published outcomes after digit or hand replantation when preservation was at or below 10°C or exceeded 6 hours.
Association Between Vitamin D Status and Nocturnal Lower Urinary Tract Symptoms: A Pooled Analysis.
This systematic review and meta-analysis assessed associations between vitamin D status or intake and nocturnal lower urinary tract symptoms (nLUTS), drawing on 17 studies: 5 randomised trials, 2 cohort studies, 4…
Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…
Effects of Polyphenols on Gut Health and Inflammation in Overweight and Obese Populations: A Systematic Review and Meta-analysis of Dose, Duration, and Food Matrix.
This systematic review and meta-analysis assessed polyphenol interventions and gut microbiota and inflammatory biomarkers in people with overweight or obesity, drawing on 32 randomized controlled trials.
2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.
This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.
Thrombin-antithrombin complex and fibrinogen predict microangiopathic acute kidney injury in patients with traumatic injuries.
This secondary analysis of a single-center randomized controlled trial examined whether early coagulation and fibrinolysis biomarkers were associated with acute kidney injury (AKI) in adults with severe traumatic…
Efficacy or Effectiveness of Zinc-Biofortified Staples in Improving Biomarkers of Zinc Status: A Systematic Review.
This systematic review assessed randomized controlled trials of zinc-biofortified staple crops and biomarkers of zinc status. Seven studies met the eligibility criteria.
Exploring the Association Between Cannabis Use and Male Reproductive Parameters: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between cannabis use and male reproductive parameters. It included 18 studies reporting sperm outcomes (5,766 patients; 6,231 samples) and hormonal outcomes…
Poly (ADP-ribose) polymerase inhibitors (PARPi) for treating advanced epithelial ovarian cancer.
This Cochrane systematic review and meta-analysis assessed randomised trials of PARP inhibitors (PARPi) in women with newly diagnosed or recurrent epithelial ovarian cancer. It included 24 studies with 8961 participants.
Home-Based, Digitally Assisted Dyadic Tai Chi Intervention for Patients With Chronic Heart Failure and Their Caregivers: Development of an Intervention and Pilot Randomized Controlled Trial.
This sequential, multiphase study developed a home-based, digitally assisted tai chi programme for people with chronic heart failure (CHF) and their caregivers, then evaluated it in a single-centre, assessor-blinded…
Intimate partner violence against women in Ethiopia: An umbrella review of systematic reviews and meta-analyses.
This umbrella review and random-effects meta-analysis synthesized six systematic reviews and meta-analyses, covering 80 primary studies and 43,785 women in Ethiopia, to estimate intimate partner violence (IPV)…
Evaluating the Feasibility, Acceptability, and Preliminary Efficacy of Virtually Delivered Dialectical Behaviour Therapy Skills Groups Among Emerging Adults in India.
This randomized controlled trial assessed the feasibility, acceptability, and preliminary efficacy of an eight-week, video-delivered dialectical behaviour therapy skills group led by student therapists in India.
Is Exercise Effective at Reducing Pain Catastrophizing in People With Chronic Nonspecific Spinal Pain? A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined whether exercise reduces pain catastrophizing in people with chronic nonspecific spinal pain.
Sperm DNA Fragmentation Index, Semen Quality, and Assisted Reproductive Technology Outcomes: A Systematic Review and Meta-analysis of Observational Studies.
This systematic review and meta-analysis of 87 observational studies assessed associations between sperm DNA fragmentation index (DFI), semen parameters, and assisted reproductive technology (ART) outcomes.
Regimens of vitamin D supplementation for women during pregnancy.
This updated Cochrane systematic review and meta-analysis assessed randomised trials of vitamin D regimens during pregnancy in women without pre-existing conditions or multiple pregnancies.
The Role of Stress-Related Biomarkers, Immune-Inflammatory Pathways, and Genetic Polymorphisms in Cognitive-Behavioral Therapies for Chronic Low Back Pain and Depression: Results From a Randomized Controlled Trial (The IMPACT Study).
This randomized controlled trial examined whether Acceptance and Commitment Therapy (ACT) or Behavioral Activation Therapy for Depression (BATD), each added to usual care, affected biomarkers or clinical outcomes in 114…
Socio-economic status, cardiovascular risk factors, and coronary atherosclerosis: a SCOT-HEART trial analysis.
This post-hoc analysis of a multicentre randomised trial examined socioeconomic status (SES) in relation to coronary CT angiography (CCTA) plaque features, management, and cardiovascular outcomes.
Imaging-Based AI for Predicting Pathological Complete Response in Esophageal Cancer After Neoadjuvant Therapy: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed imaging-based AI models for predicting pathological complete response after neoadjuvant therapy for esophageal cancer, separating internal from external validation.
Predictors and prognostic impact of spontaneous portal vein thrombosis recanalization in cirrhosis: An individual patient data meta-analysis.
This individual patient data meta-analysis pooled cohort studies of patients with cirrhosis and portal vein thrombosis (PVT) who were not receiving anticoagulation.
Effect of dietary counselling on educational disparities in cardiometabolic health from childhood to adulthood.
This randomized controlled study examined whether parental education was associated with cardiometabolic health from childhood to adulthood and whether it modified the effects of dietary counselling.
Cutaneous Silent Period-Based Comparison of Dorsal Root Ganglion Pulsed Radiofrequency and Transforaminal Epidural Steroid Injection in Lumbar Radicular Pain: A Randomized Controlled Trial.
This prospective, single-blind randomized controlled trial compared dorsal root ganglion pulsed radiofrequency (DRG-PRF) with transforaminal epidural steroid injection (TFESI) in 36 patients with chronic unilateral…
Polyamine Dysregulation in Metabolic Dysfunction-associated Steatotic Liver Disease: a Systematic Review of Human Observational Evidence.
This systematic review evaluated human observational evidence linking polyamines with MASLD severity and related hepatic or metabolic outcomes.
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