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643 articles
November 202624
Thrombocytapheresis for Extreme Thrombocytosis: A 20-Year Single-Center Experience With Acute and Chronic Use in Myeloproliferative Neoplasms.
Thrombocytapheresis is an established adjunctive therapy for rapid platelet cytoreduction in patients with extreme thrombocytosis, particularly in myeloproliferative neoplasms (MPNs), where it is typically used…
Measles-like hypermutation of a Newcastle disease virus drives fatal encephalitis during BCMA × CD3 T-cell-redirecting immunotherapy.
A patient with multiple myeloma receiving maintenance teclistamab, daratumumab, and lenalidomide developed rapidly progressive brainstem-cerebellar encephalitis.
ID-SCAN: a functional MRI protocol for neurophenomenological phenotyping of dissociative identity disorder without trauma provocation.
A woman with dissociative identity disorder and persistent co-consciousness between two identity-agents completed ID-SCAN, a functional MRI protocol that did not use trauma provocation.
Alfred Kocher technique for prevention of patient-prosthesis mismatch in paediatric patients.
A 7-year-old girl requiring aortic valve replacement had a functionally unicuspid aortic valve. Although the Ross procedure is generally favored in children, an intraoperative bicuspid pulmonary valve made durable…
Acute Ethylene Glycol Poisoning Following Accidental Mineral Oil Ingestion With Severe Metabolic Acidosis, Acute Kidney Injury, Respiratory Failure, and Delayed Neurological Sequelae: A Case Report.
A 57-year-old man became dizzy, vomited, and developed altered consciousness progressing to coma after accidentally ingesting mineral oil containing ethylene glycol.
Optimizing survival and long-term outcomes in complex pediatric digital amputations: a case report with a 6.5-year follow-up.
A 1.5-year-old boy sustained complete thermal-crush amputations of the left index, middle, and ring fingers in an industrial sealer injury.
Clinical Reasoning: A 55-Year-Old Woman With a Hyperkinetic Movement Disorder, External Ophthalmoplegia, and Myopathy.
A 55-year-old woman was evaluated for an 8-year history of hyperkinetic movements. Her examination and clinical picture also included mild ataxia, spasticity in the lower limbs, external ophthalmoplegia, and myopathy.
Coracoid Process Osteochondroma: Diagnostic Considerations and Detailed Approach for Management: Case Report and Literature Review.
A 21-year-old woman was found to have an osteochondroma arising from the tip of the coracoid process. The report describes preoperative clinical assessment and radiological investigation, with histopathological…
Primary Synovial Sarcoma of the Thyroid Gland Presenting With Early Pulmonary Metastasis: Diagnostic Pathway, SS18 Gene Fusion Confirmation, and Clinical Course.
A 47-year-old woman presented with dysphagia and a left-sided neck mass. Initial fine-needle aspiration was non-diagnostic; repeat sampling suggested a spindle cell neoplasm.
Hyoid Bone Fracture in a Patient as a Rare Cause of Persistent Postoperative Dysphagia Following Anterior Cervical Discectomy and Fusion.
A 76-year-old woman developed severe, persistent dysphagia and progressive odynophagia after C3–5 anterior cervical discectomy and fusion.
Fetal myelomeningocele repair: Rome Fondazione Policlinico A. Gemelli IRCCS experience.
A fetus with distal lumbar myelomeningocele was assessed by fetal MRI, which showed a 23 × 11-mm defect, ventricular dilatation, and Chiari II malformation. Open fetal repair was performed at 25 weeks of gestation.
Rheumatoid factor positivity in ANCA-negative eosinophilic granulomatosis with polyangiitis: cardiac mimicry, mononeuritis multiplex, and long-term outcome in a case-based systematic review.
A 42-year-old woman with long-standing asthma and rheumatoid factor (RF) of 322 IU/mL presented with myocardial infarction-like cardiac involvement despite non-obstructive coronary arteries.
Multidisciplinary management of disseminated tuberculosis with tuberculous meningitis and active hepatitis B in a critically ill pregnant woman in the third trimester: a case report.
A 24-year-old woman at 30 weeks’ gestation presented with headache, vomiting, fever, and nuchal rigidity. Cerebrospinal fluid findings confirmed tuberculous meningitis, and chest CT showed diffuse miliary nodules…
Cannula exchange for refractory cannula infections during Berlin Heart EXCOR support: a case report.
A 4-year-old girl with truncus arteriosus and severe heart failure received Berlin Heart EXCOR (BHE) support after complex cardiac surgery.
Impact of nasogastric administration using the simple suspension method on serum tirabrutinib levels: A case report.
An 82-year-old man with relapsed primary central nervous system lymphoma began tirabrutinib at 320 mg/day while fasting. As dysphagia progressed, administration changed from swallowing tablets to nasogastric delivery by…
Arterial-to-End-Tidal CO₂ Gradient Direction as a Differential Diagnostic Clue During Sudden Hypercapnia in Thoracoscopic Surgery with Capnothorax: A Report of 2 Cases.
Two men undergoing thoracoscopic surgery with CO₂ insufflation developed abrupt rises in end-tidal CO₂ (EtCO₂). In the first, the rise coincided with severe hypotension and bradycardia; arterial blood gas showed PaCO₂…
Multiorgan [ 18 F]florbetapir PET/CT uptake in multiple myeloma-associated systemic AL amyloidosis: a case report.
A 77-year-old man with multiple myeloma underwent whole-body [18F]florbetapir PET/CT because AL amyloidosis was suspected. The scan showed prominent tracer retention in the myocardium, thyroid, lungs, parotid glands…
Intractable Nausea and Vomiting: A Key Feature of Neuromyelitis Optica Spectrum Disorder.
A 22-year-old woman had five weeks of intractable nausea, vomiting, and hiccups. Delayed gastric emptying led to an initial diagnosis of gastroparesis, but symptoms persisted despite antiemetic and prokinetic therapy.
Simultaneous Infection Control and Reconstruction Using Continuous Local Antibiotic Perfusion in Septic Knee With Extensive Soft Tissue Defect: A Case Report.
A 69-year-old woman presented 2.5 months after patellar fracture fixation with methicillin-resistant Staphylococcus aureus infection, septic knee arthritis, and a 12×8 cm anterior soft tissue defect with joint exposure.
Multifocal intradural extramedullary myxopapillary ependymoma of the spine.
A 34-year-old man presented with sudden severe non-radicular low-back pain but no neurological deficit. MRI showed multiple enhancing intradural extramedullary lesions from T12-L1 to S1; the dominant T12-L1 lesion…
Clinical Reasoning: A 33-Year-Old Man With Rapidly Progressive Ataxia.
A 33-year-old man with AIDS developed subacute progressive confusion, blurred vision, diplopia, and generalized cerebellar ataxia after hospitalizations for opportunistic infections.
Clinical Reasoning: A 69-Year-Old Female Patient With Rapid-Onset Levodopa-Responsive Rest Tremor, Parkinsonism, and Gait Freezing.
A 69-year-old woman developed a unilateral resting tremor that rapidly spread to the opposite arm and then the legs. Within 3 months, she had generalized parkinsonism, a shuffling gait with prominent freezing, and…
Pearls & Oy-sters: Anti-GABA A Receptor Encephalitis Presenting as Fulminant Hemicerebellitis in a 5-Year-Old Girl.
A previously healthy 5-year-old girl developed acute neurologic decline after several days of fever and malaise. CT showed severe right cerebellar inflammation and edema with fourth-ventricle effacement, prompting…
Fresh Osteochondral Allograft Transplantation as a Salvage Procedure Following Failed Fixation of Osteochondritis Dissecans of the Lateral Femoral Condyle: A Case Report.
A 19-year-old competitive athlete developed recurrent left-knee pain and mechanical locking after fixation of osteochondritis dissecans of the lateral femoral condyle.
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