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2000 articles
October 202624
Spontaneous gene mutation encounters a paternal genetic variant: Nemaline myopathy: a case report and literature review.
A 21-year-old man had progressive weakness beginning in the distal lower limbs at age 3, later affecting proximal and masticatory muscles.
Influenza A (H1N1) virus infection complicated by checkpoint inhibitor pneumonitis: A case report.
After neoadjuvant immunotherapy, a patient developed respiratory dysfunction and progressive pulmonary lesions. Imaging and positive influenza A (H1N1) testing, interpreted alongside the immunotherapy history and…
Arthroscopic-assisted uniportal spinal surgery with bone-anchored annular repair for far lateral lumbar disc herniation: A case report.
A 50-year-old woman had refractory lumbosacral and gluteal pain followed by right L3–L4-distribution radicular pain, limiting walking to less than 20 minutes despite conservative treatment.
Bilateral lower limb dysfunction due to acute hematoma in the lumbar ligamentum flavum: A case report and literature review.
A 71-year-old man developed sudden lower back pain without an identifiable trigger, followed by worsening pain, numbness, and weakness in both legs.
Moxibustion for depression: A meta-analysis.
This meta-analysis assessed moxibustion, alone or alongside other therapies, for depression. It included 15 randomized controlled trials with 1510 patients, comparing moxibustion with sham treatment, no treatment, or…
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
Bone phenotype of patients with genetic forms of lipodystrophy: a systematic review of literature.
This systematic review examined bone manifestations in people with genetic lipodystrophies, using human studies identified through searches of PubMed, EMBASE, and the Cochrane Library.
The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.
This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.
Multimodal imaging features of nuclear protein in testis carcinoma of the submandibular gland: a case report.
A 32-year-old man presented with a painless left submandibular mass that enlarged from 2 cm to approximately 4 cm within 1 month, with new ipsilateral pharyngeal and periauricular pain.
Dysregulation of glycogen metabolism in cardiomyopathy caused by glycogenin-1 (GYG1) missense variants.
The report describes a new case of glycogen storage disease type 15 (GSD15), alongside analysis of heart explants from two previously reported patients.
Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.
This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…
Seizures Secondary to Aconitum Plant Poisoning: a case report.
A 53-year-old man developed ventricular tachycardia progressing to ventricular fibrillation and cardiac arrest after drinking homemade Aconitum kusnezoffii-infused liquor.
Denecimig (Mim8) prophylaxis once every 2 weeks for hemophilia A with or without inhibitors: 26-week results from FRONTIER4.
This open-label extension study evaluated every-2-week (Q2W) denecimig prophylaxis in patients aged ≥12 years with hemophilia A, with or without inhibitors, who had previously received denecimig in a phase 2 study and…
Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.
This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…
Ectopic thyroid tissue accompanied by distinct blood supply and lymphoid tissue within the carotid sheath - a case report.
A 42-year-old man had an asymptomatic right-sided neck mass detected during a routine examination. Ultrasound showed a normally located thyroid and a well-defined 1.3 cm × 0.9 cm × 0.5 cm mass with echotexture similar…
Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.
This mixed methods study evaluated recruitment, engagement, completion, and participant experiences in Dialysafe, a digital education and peer-mentoring intervention at 10 hemodialysis centers.
Participant Characteristics Associated With Loneliness Reduction During a Digital Social Robot Intervention Among Older Adults Living Alone in Japan: Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial examined whether participant characteristics were associated with changes in loneliness during a digital social robot intervention among community-dwelling older…
Amygdala neurofeedback as an adjunct to residential dialectical behavior therapy for borderline personality disorder: a pilot randomized controlled trial.
This pilot randomized controlled trial tested whether real-time fMRI amygdala neurofeedback (amy-NF) adds benefit to residential dialectical behavior therapy (DBT) for people with borderline personality disorder and…
Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.
Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.
Effect of Vasopressin Infusion Rate on Vancomycin Dose Adjustment in Pediatric Central Diabetes Insipidus: Grand Round/A Case Study.
A 9-month-old infant with trauma-associated central diabetes insipidus received continuous arginine vasopressin (AVP) and vancomycin for suspected postoperative surgical-site infection.
Additive effects of active vitamin D3 or vitamin E administration on therapeutic lower-limb home exercise for knee osteoarthritis: A pilot prospective randomized controlled trial.
This pilot prospective randomized controlled trial assessed whether active vitamin D3 or vitamin E added benefit to home exercise in postmenopausal women with symptomatic knee osteoarthritis.
Hyaluronic acid-based skin booster with glutathione combined with 1064-nm Nd:YAG laser and oral tranexamic acid for melasma: A prospective comparative study.
This randomized comparative study evaluated whether intradermal hyaluronic acid-based glutathione (HA-GSH) improves outcomes when added to low-fluence 1064-nm Q-switched Nd:YAG laser and oral tranexamic acid in Chinese…
Complete remission of minimal change disease after antiviral monotherapy in a patient with immune-active chronic hepatitis B: A case report.
A 42-year-old woman presented with generalized edema, weight gain, hypoalbuminemia, and nephrotic-range proteinuria, with a urine protein-to-creatinine ratio of 4.3 and preserved renal function.
SGLT2 inhibitors in diabetic biopsy proven MASH patients: A systematic review and meta-analysis.
This systematic review and random-effects, single-arm meta-analysis assessed SGLT2 inhibitors in patients with diabetes and biopsy-proven MASH. Seven trials contributed 110 patients receiving the intervention.
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