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2000 articles

October 202624

Clinical ResearchCardiology

Vascular health after quitting smoking or switching to e-cigarette use: a systematic review of prospective studies with GRADE assessment.

This systematic review assessed prospective evidence on vascular function after smoking cessation or switching to exclusive e-cigarette use among adult smokers.

Eur J Prev CardiolOct 28, 2026Read summary
Clinical ResearchCardiology

Mitral regurgitation in patients with heart failure and reduced ejection fraction: insights from GALACTIC-HF.

This analysis of the randomized, multicentre GALACTIC-HF trial examined mitral regurgitation (MR) and outcomes in patients with heart failure and reduced ejection fraction.

Eur J Heart FailOct 28, 2026Read summary
Clinical ResearchCardiology

Association between chronic opioid exposure and cardiovascular disease: a systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between chronic opioid exposure—including opium use, opioid use disorder, and prescription opioids—and cardiovascular disease in human studies.

Eur J Prev CardiolOct 28, 2026Read summary
Clinical ResearchGeriatricsOpen access

Can Photobiomodulation improve healing of category II-III pressure ulcers in frail older adults? A quasi-experimental 24-month follow-up study.

This quasi-experimental study compared adjunctive photobiomodulation with standard care for category II and III pressure ulcers in frail adults aged 70 years or older receiving municipal home healthcare.

PLoS OneOct 28, 2026Read summary
Clinical ResearchCardiology

Home-based nurse-led self-management support for heart failure: a randomized controlled trial.

This parallel-group randomized controlled trial assessed a 12-week, nurse-led home programme of tailored self-management support and follow-up for adults aged 40–75 years with NYHA class I–III heart failure and ejection…

Prim Health Care Res DevOct 28, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Efficacy of a Gamified Training Program for Improving Occupational Health and Safety Knowledge Among Italian Secondary School Students: A Randomized Controlled Field Trial.

This cluster-randomized controlled field trial assessed whether a gamified occupational health and safety (OHS) program improved knowledge among Italian secondary school students.

Games Health JOct 28, 2026Read summary
Clinical ResearchFamily Medicine

An mHealth Stress Management Intervention for Latino Millennial Caregivers: Pilot Feasibility Randomized Controlled Trial.

This pilot feasibility randomized controlled trial evaluated a culturally tailored, automated mobile intervention for stress management and emotional regulation among Latino millennial caregivers in the United States.

JMIR Form ResOct 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Long-term gynecological symptoms and ultrasound and reproductive outcomes after monofilament vs multifilament uterine closure at Cesarean delivery: secondary analysis of randomized controlled trial.

This secondary analysis of a randomized controlled trial compared long-term outcomes after monofilament versus multifilament absorbable uterine closure at Cesarean delivery.

Ultrasound Obstet GynecolOct 27, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and Safety of Apixaban Thromboprophylaxis According to Baseline Chemotherapy Class in High-Risk Ambulatory Cancer Patients: A Post Hoc Analysis of the AVERT Trial.

This post hoc analysis of the randomized, double-blind AVERT trial examined apixaban thromboprophylaxis by baseline chemotherapy class in 563 ambulatory patients with cancer starting chemotherapy.

Cancer MedOct 27, 2026Read summary
Clinical ResearchPsychiatry

Measurement properties of anhedonia-related patient-reported outcome measures in depression-related populations: A COSMIN systematic review.

This COSMIN systematic review evaluated the measurement properties of anhedonia-related patient-reported outcome measures in depression-related populations.

J Affect DisordOct 27, 2026Read summary
Clinical ResearchOncology (Medical)

Antibiotics and outcomes of cancer immunotherapy: An updated meta-analysis and clinical applications.

This updated meta-analysis examined antibiotic exposure and outcomes among 97,850 patients with cancer treated with immune checkpoint inhibitors (ICI), drawing on 116 cohorts.

Cancer CellOct 27, 2026Read summary
Clinical ResearchPsychiatry

Hippocampal subfield functional connectivity alterations in major depressive disorder: A systematic review and meta-analysis.

This systematic review and meta-analysis examined functional connectivity (FC) involving hippocampal subfields or subregions in major depressive disorder (MDD), comparing findings with healthy controls and summarizing…

J Affect DisordOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Exposure to natural disasters and vaccination indicators: a systematic review and directions for future research.

This systematic review examined peer-reviewed research on exposure to natural disasters and vaccination indicators, including vaccine administration, coverage, and rates.

VaccineOct 27, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing.

This randomized controlled trial tested whether personalizing cognitive remediation (CR) by baseline early auditory processing (EAP) status improved outcomes in 184 outpatient adults with schizophrenia.

Schizophr BullOct 27, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of Adding Esketamine to Patient-Controlled Intravenous Analgesia on Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether adding esketamine to postoperative patient-controlled intravenous analgesia (PCIA) reduces rebound pain after interscalene brachial plexus block in patients undergoing…

Drug Des Devel TherOct 27, 2026Read summary
Clinical ResearchPsychiatry

Psychedelics and psychosis: A systematic review of recent-era studies (1984-2025).

This systematic review examined evidence from 1984–2025 on classical psychedelic use and psychotic symptoms, drawing on 52 papers, including population studies, clinical trials, emergency and toxicology data, and case…

J PsychopharmacolOct 27, 2026Read summary
Clinical ResearchAnesthesiology

Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.

This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…

Acta Anaesthesiol ScandOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

E-Cigarettes with and without Behavioral Support for Smoking Cessation.

This randomized controlled trial compared an e-cigarette starter pack alone, the starter pack plus multisession telephone-based behavioral support, and automated supportive messages among people who smoked and were…

NEJM EvidOct 27, 2026Read summary
Clinical ResearchPulmonology

Comparison of the Safety and Efficacy of Remimazolam for Sedation in Adults Undergoing Fiberoptic Bronchoscopy: A Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis of randomized controlled trials compared remimazolam with other sedatives in adults undergoing fiberoptic bronchoscopy.

J Bronchology Interv PulmonolOct 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effectiveness of theory-based educational interventions on fertility and childbearing intentions: a systematic review and meta-analysis among Iranian populations.

This systematic review and meta-analysis assessed theory-based educational interventions and fertility or childbearing intentions among Iranian populations.

Hum Fertil (Camb)Oct 27, 2026Read summary
Clinical ResearchPediatrics

Endobronchial Valves for Persistent Air Leak and Bronchopleural Fistula in Children: A Systematic Review of Indications, Procedural Approaches, and Outcomes.

This systematic review examined bronchoscopic endobronchial or intrabronchial valve placement for persistent air leak, bronchopleural fistula, or pneumothorax with ongoing air leak in children and late adolescents.

J Bronchology Interv PulmonolOct 27, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Rare and Novel Hepatitis C Virus Genotype Subtypes and Response to Sofosbuvir/Velpatasvir in A5360 (MINMON) Clinical Trial.

This analysis of samples from the multicountry ACTG A5360 (MINMON) clinical trial characterized rare and novel hepatitis C virus (HCV) subtypes and assessed baseline resistance-associated substitutions and response to…

J Viral HepatOct 27, 2026Read summary
Case ReportObstetrics & Gynecology

Vaginal Angiomyofibroblastoma in a Patient With Warkany Syndrome (Mosaic Trisomy 8): A Case Report.

A 27-year-old nulliparous woman with constitutionally confirmed mosaic trisomy 8 presented with a protruding vaginal mass. MRI showed a well-defined, homogeneously enhancing mid-vaginal lesion and incidentally…

J Obstet Gynaecol ResOct 27, 2026Read case
Clinical ResearchNeurology

Measuring the impact of migraine: a systematic review of the measurement properties of MIDAS, HIT-6, and MSQoL.

This systematic review compared the measurement properties of MIDAS, HIT-6, and MSQoL for assessing migraine impact. Following COSMIN methods, it included 22 studies with 20,455 participants.

Arq NeuropsiquiatrOct 27, 2026Read summary

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