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2000 articles
October 202624
Efficacy and Safety of Short-Course Radiotherapy Alone or Combined With Consolidation Chemotherapy Versus Conventional Long-Course Chemoradiotherapy for Locally Advanced Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials.
This meta-analysis of randomized controlled trials compared short-course radiotherapy (SCRT), with or without consolidation chemotherapy, against long-course chemoradiotherapy (LCCRT) for locally advanced rectal cancer.
Subgroup Analysis of Pooled Phase 3 Efficacy Data From Two Randomized Trials of Gepotidacin Versus Nitrofurantoin in Uncomplicated Urinary Tract Infections (EAGLE-2 and EAGLE-3) Including Participants With Uropathogens Not-Susceptible to Nitrofurantoin.
This pooled subgroup analysis of two phase 3 randomized trials compared gepotidacin with nitrofurantoin in female participants aged ≥12 years with uncomplicated urinary tract infections.
A NETwork meta-analysis with COST-effectiveness evaluation of pharmacological treatments for heart failure with reduced ejection fraction: NET-COST-HFrEF.
This network meta-analysis of 47 randomized controlled trials involving 75,978 patients with heart failure with reduced ejection fraction assessed guideline-directed drug combinations and their cost-effectiveness.
A Randomized, Double-Blind, Placebo-Controlled Study of the PD-1 Inhibitor Cetrelimab in Chronic Hepatitis B.
This randomized, double-blind, placebo-controlled study assessed the safety, activity and pharmacokinetics of a single low dose of the PD-1 inhibitor cetrelimab in adults with chronic hepatitis B virologically…
POSTERIOR DISLOCATION OF POSTERIOR LAMELLAR CORNEAL GRAFT WITH VIABLE ENDOTHELIAL CELLS.
A middle-aged man with prior traumatic eye injury and pars plana vitrectomy, lensectomy, and scleral-sutured intraocular lens fixation developed corneal edema requiring Descemet stripping automated endothelial…
Proof-of-Concept Phase 2a Trial of VH4524184: An Emerging Third-Generation Integrase Strand Transfer Inhibitor With an Enhanced Resistance Profile.
This randomized, double-blind, placebo-controlled phase 2a trial assessed short-course oral VH-184 monotherapy in adults with HIV-1 who were antiretroviral-therapy naive and had HIV-1 RNA ≥ 3000 copies/mL.
Can neurodevelopmental disorders be part of brain-lung-thyroid syndrome? A case report.
A 12-year-old girl with an NKX2-1 gene mutation was reported to have an articulation disorder and a specific learning disorder.
IMPROVEMENT OF MACULOPATHY ASSOCIATED WITH CAVITARY OPTIC DISK ANOMALIES TREATED WITH TOPICAL ANTIGLAUCOMA MEDICATIONS.
Two young women developed worsening visual acuity associated with serous retinal detachment and maculopathy in the setting of cavitary optic disk anomalies.
Complex cervical venous drainage with a common facial-paralaryngeal anastomosis receiving the superior thyroid vein.
A 68-year-old woman’s archived CT angiogram showed a complex right cervical venous arrangement. The common facial vein and a separate lingual–parapharyngeal–paralaryngeal channel each drained into the right internal…
Pseudodominant inheritance in paraplegin (SPG7)-associated CPEO-ataxia syndrome.
A 47-year-old man presented with progressive external ophthalmoplegia, ptosis, gait disturbance and spasticity. Over ten years, he developed slowly progressive spastic ataxia with ocular motor involvement and neurogenic…
Immunogenicity and Safety of Coadministration of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine and a COVID-19 mRNA Vaccine in Adult s Aged ≥50 Years: A Phase 3, Randomized, Noninferiority Trial.
This phase 3, open-label, multicenter randomized noninferiority trial compared coadministration of an AS01E-adjuvanted RSV prefusion F vaccine and an Omicron XBB.1.5 COVID-19 mRNA vaccine with administration…
Acute pericarditis caused by Kocuria kristinae with successful withdrawal from hemodialysis: a case report.
A 47-year-old man developed dialysis-dependent acute kidney injury after severe heatstroke. About a month later, imaging showed a marked increase in cardiothoracic ratio, and echocardiography demonstrated a substantial…
IDIOPATHIC ACUTE EXUDATIVE POLYMORPHOUS VITELLIFORM MACULOPATHY: A 5-YEAR FOLLOW-UP.
A patient with idiopathic acute exudative polymorphic vitelliform maculopathy had 20/20 visual acuity in both eyes. Examination showed symmetrical multifocal serous retinal detachments and foveal vitelliform lesions…
Therapeutic plasma exchange improves survival in alcohol-related acute-on-chronic liver failure: a randomized controlled trial.
This randomized controlled trial evaluated therapeutic plasma exchange (PLEX) plus standard medical therapy versus standard therapy alone in 100 patients with alcohol-related acute-on-chronic liver failure.
Multimedia versus audio-based education for improving dentists' nutrition-related knowledge and behavior: A randomized comparative study.
This randomized comparative trial assessed whether multimedia or audio-based education improved nutrition-related knowledge and self-reported behavior among 166 general dentists in Tehran.
SARS-CoV-2 Vaccination and Attenuation of Breakthrough Infection Severity: A Systematic Global Review and Meta-analysis.
This systematic review and meta-analysis examined whether COVID-19 vaccination attenuates disease severity among people with breakthrough infections, using global observational studies reporting matched…
Efficacy and Safety of Ushaq Capsule as Adjunctive Therapy in Patients With Lumbar Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial at Imam Khomeini Hospital, Tehran, Iran.
This double-blind, randomized, placebo-controlled trial evaluated Ushaq capsules as adjunctive therapy in 68 patients with lumbar radiculopathy.
OPTIC DISK PIT: A TRIGGER FOR SECONDARY MULTIPLE EVANESCENT WHITE DOT SYNDROME.
A 41-year-old man with a right optic disk pit presented with right-eye visual loss and photopsia; visual acuity was 20/100.
Impact of Intermittent Preventive Treatment for Malaria in Pregnancy With Sulfadoxine-Pyrimethamine, Dihydroartemisinin-Piperaquine, and Their Combination on Infant Outcomes: A Randomized Controlled Trial.
This double-blind randomized controlled trial compared infant malaria and growth outcomes after maternal intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine…
Long-term impact of aficamten on patient-reported outcome measures in obstructive hypertrophic cardiomyopathy: results from FOREST-HCM.
This open-label extension study assessed longer-term patient-reported outcomes with aficamten in people with obstructive hypertrophic cardiomyopathy who had completed an aficamten trial.
TENON CAPSULE GRAFT AS A SEALANT IN PEDIATRIC RETINAL DETACHMENT.
The report describes four pediatric cases of complex retinal detachment associated with infantile high-myopic macular holes, Morning Glory Syndrome, or optic disk pit maculopathy.
Robot-assisted versus conventional cranial stereotactic neurosurgery: a systematic review and meta-analysis of targeting accuracy, procedural efficiency, and safety.
This systematic review and meta-analysis compared robot-assisted with conventional cranial stereotactic neurosurgery across 21 comparative studies, examining targeting accuracy, procedural efficiency, safety and…
Pars plana vitrectomy with silicone oil versus pars plana vitrectomy alone for postoperative endophthalmitis: A randomized controlled trial.
This prospective randomized controlled trial compared pars plana vitrectomy (PPV) with 1000-cSt silicone oil (SO) tamponade against PPV alone in 40 eyes with severe post-phacoemulsification endophthalmitis unresponsive…
Vulvar High-Grade Squamous Intraepithelial Lesion in Primary Lymphedema With Severe Genital Lymphorrhea: A Case Report.
A 37-year-old woman with childhood-onset primary lymphedema developed recurrent right leg and genital swelling after 31 years of clinical quiescence, with vulvar erythema, follicular lesions, and persistent lymphorrhea.
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