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2000 articles
October 202624
Clinical Reasoning: A 60-Year-Old Woman With Progressive Dysarthric Speech and Gait Instability.
A 60-year-old woman developed progressive dysarthria and gait instability over 2 months, with chronic constipation and substantial weight loss.
Maternal and Fetal Safety Outcomes of Thrombolytics for Ischemic Stroke in Pregnancy: A Systematic Review and Aggregated Case Series.
This systematic review and Bayesian aggregated case series examined maternal and fetal outcomes after thrombolytic treatment during pregnancy.
Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting as Acute Psychosis in a Renal Transplant Recipient Under Chronic Immunosuppression.
A 38-year-old renal transplant recipient taking tacrolimus and mycophenolate presented with abrupt psychosis, including delusions, auditory hallucinations, and severe agitation.
Unmasking Panic Disorder in Adults with Leukemia: A Systematic Review of Prevalence, Risk Factors, and Management.
This PRISMA-guided systematic review examined panic disorder and anxiety in adults with leukemia, searching four databases for studies published from 2015 to July 20, 2025.
Asymptomatic Tattoo-Associated Cutaneous Nontuberculous Mycobacterial Infection: Case Report.
An immunocompetent 28-year-old man presented with monomorphic papules bearing collarettes of scale, diffusely distributed but confined to recently tattooed skin.
The effect of acupuncture-rehabilitation therapy on brain functional plasticity in motor aphasia after ischemic stroke: a randomized clinical neuroimaging trial.
This randomized clinical neuroimaging trial assigned 26 patients with motor aphasia after ischemic stroke to conventional rehabilitation (CR) or CR plus acupuncture-rehabilitation (A-R); 26 healthy controls provided…
The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.
This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…
Survival Outcomes in Metastatic Colorectal Cancer Patients with BRAF Mutations Undergoing Targeted Chemotherapy: A Reconstructed Individual Patient Data Meta-Analysis of Randomized Controlled Trials.
This reconstructed individual patient-data meta-analysis of 18 randomized controlled trials examined survival outcomes across targeted treatment classes in BRAF V600E-mutant metastatic colorectal cancer.
Risk factors for Post-COVID-19 Syndrome in patients hospitalized for severe acute respiratory syndrome: systematic review and meta-analysis.
This systematic review and meta-analysis examined factors associated with post-COVID-19 syndrome among patients discharged after hospitalization for severe acute respiratory syndrome.
Delayed Presentation of Neonatal Omphalitis with Suspected Invasive Soft-Tissue Infection and Late-Onset Sepsis Following Non-Sterile Home Delivery: A Case Report.
A 19-day-old girl presented with fever, poor feeding, abdominal distension, purulent umbilical discharge, periumbilical inflammation and necrotic-appearing tissue after a non-sterile home delivery and cord tying with…
Metabolic, hormonal, and reproductive effects of GLP-1 receptor agonizts in hyperandrogenic insulin-resistant women: a systematic review.
This systematic review evaluated GLP-1 receptor agonists for metabolic, hormonal, and reproductive outcomes in adult women with hyperandrogenic insulin-resistant conditions, principally polycystic ovary syndrome and…
MLH1 AND MSH2 PROTEIN EXPRESSION LOSS AND MICROSATELLITE INSTABILITY IN COLORECTAL ADENOMAS OF PATIENTS WITH LYNCH SYNDROME: A SYSTEMATIC REVIEW AND META-ANALYSIS.
This systematic review and meta-analysis assessed the relationship between microsatellite instability (MSI) and loss of MLH1 or MSH2 expression in colorectal adenomas from people with Lynch syndrome.
Second-hand smoke exposure linked to TB infection or disease in children/adolescents: systematic review and meta-analysis.
This PROSPERO-registered systematic review and meta-analysis examined observational evidence on household second-hand smoke (SHS) exposure and tuberculosis (TB) outcomes in children and adolescents aged 0–18 years in…
Post-transplant follow-up for kidney transplant recipients: a systematic review of clinical practice guidelines.
This systematic review compared clinical practice guidelines for post-transplant follow-up of kidney transplant recipients, assessing methodological quality and recommendations for surveillance.
Bridging Nonconsecutive Esketamine Weeks with Bupropion and Over-the-Counter Dextromethorphan.
A 52-year-old woman with treatment-resistant depression and bipolar II disorder achieved remission with weekly intranasal esketamine, but depressive symptoms returned when sessions were more than 10 days apart.
Treatment of Refractory Descemet Membrane Detachment via Repeat Descemetopexy: A Case Report.
An 82-year-old man with age-related cataract and a history of bilateral pterygium surgery with corneal scarring developed Descemet membrane detachment during phacoemulsification and intraocular lens implantation.
Slow Flow/No-Reflow After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Meta-Analysis.
This meta-analysis synthesized clinical, laboratory, angiographic, and procedural factors associated with coronary slow flow/no-reflow after primary PCI for STEMI.
How do adult migrants with active TB adhere to care in high-income countries? A systematic review.
This systematic review examined adherence to the TB care process among adult migrants with active TB in high-income countries.
Factors associated with missed video directly observed therapy sessions among persons with TB.
This secondary analysis of the DOT Selfie randomised controlled trial in Uganda examined factors associated with missed video directly observed therapy (VDOT) submissions during TB treatment.
Visual rigid laryngoscope versus Macintosh laryngoscope using low-dose relaxants in thyroid surgery.
This single-centre randomized controlled trial compared visual rigid laryngoscopy (VRL) with Macintosh laryngoscopy for tracheal intubation in patients undergoing elective thyroid surgery with intraoperative…
Efficacy and Safety of Nafamostat Mesilate Injection in Patients Receiving Continuous Renal Replacement Therapy: A Meta-Analysis.
This meta-analysis assessed the efficacy and safety of nafamostat mesilate injection versus no anticoagulation in patients receiving continuous renal replacement therapy (CRRT).
Effects of Parent-Involved Digital Health Interventions on Adiposity-Related Outcomes and Behaviors in Children and Adolescents With Overweight or Obesity: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined randomized controlled trials of parent-involved digital health interventions for children and adolescents with overweight or obesity.
Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors.
This Phase I, open-label, 3 + 3 dose-escalation study assessed safety, tolerability, pharmacokinetics, and preliminary antitumor activity of once-daily oral omeprazole plus trimetazidine, two fatty acid oxidation…
Endpoint-specific mortality associated with malignancy among adults with sepsis or septic shock: a systematic review and meta-analysis.
This systematic review and meta-analysis examined mortality among adults with sepsis or septic shock, comparing patients with and without malignancy.
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