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2000 articles
October 202624
Emergence of linezolid resistance associated with 23S rRNA G2576T mutations in vancomycin-resistant Enterococcus faecium during oxazolidinone therapy.
A patient developed persistent vanA-positive vancomycin-resistant Enterococcus faecium bacteremia after allogeneic hematopoietic stem cell transplantation.
Stroke thrombectomy of a mural thrombus in a severe dolichoectatic basilar artery with double parallel large stent retrievers and Sofia 88.
An older adult presented with severe acute ischemic stroke from a mural thrombus on the posterior wall of the mid-basilar artery.
Bee Sting-Associated Kounis Syndrome Presenting as Myocardial Infarction: A Case Report and Systematic Review with Age-Based Analysis.
A 44-year-old man presented with myocardial infarction after a probable bee sting-associated allergic reaction and was considered to have Kounis syndrome, an acute coronary syndrome linked to hypersensitivity.
Epigenetic insights into anti-tuberculosis drug-induced liver injury: A systematic review of DNA methylation as a potential biomarker.
This systematic review assessed whether DNA methylation patterns are associated with susceptibility to anti-tuberculosis drug-induced liver injury (ATDILI).
Daily Zinc Supplementation for Infection Prevention in Children With Sickle Cell Anemia: The ZIPS-2 Randomized Clinical Trial.
The ZIPS-2 randomized, double-blind, placebo-controlled trial evaluated daily zinc for infection prevention in children aged 1 to 4.99 years with sickle cell anemia in Uganda.
Elinzanetant in postmenopausal women with sleep disturbance: results from the randomized, phase II NIRVANA study.
The phase II NIRVANA randomised trial assessed elinzanetant versus placebo in 110 postmenopausal women aged 40–65 years with moderate-to-severe vasomotor symptoms and objectively measured sleep disturbance.
Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.
The phase 3, multicenter, randomized CHIPS trial compared cold-stored platelets (CSPs; up to 21 days) with room-temperature platelets (RTPs; up to 7 days) in pediatric and adult patients receiving platelet transfusions…
Efficacy of Ibuprofen Versus Acetaminophen for Acute Fever Management in Febrile Children: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials compared ibuprofen with acetaminophen for acute fever management in children. Seven studies contributed to the quantitative synthesis.
Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease.
A man in his 50s with mild cognitive impairment and the Alzheimer disease risk-associated p.R47H TREM2 variant received 30 doses of aducanumab (cumulative dose 280 mg/kg) over 4.5 years in a clinical trial.
Successful Kidney Transplantation Under Combined Spinal-Epidural Anesthesia in a Patient With a History of Left Pneumonectomy Due to Bronchiectasis.
A 33-year-old man with end-stage kidney disease from biopsy-proven AA amyloidosis was assessed for preemptive living-donor kidney transplantation.
Long-Term Quantitative MRI and Quality-of-Life After Endovascular Therapy in Acute Ischemic Stroke - A MR CLEAN-NO IV Substudy.
This long-term substudy of the MR CLEAN-NO IV randomised trial examined quantitative MRI and quality of life three years after acute ischaemic stroke.
Atypical presacral masses in Currarino syndrome: a case series.
The report describes three patients with Currarino syndrome, a congenital condition involving a sacral anomaly, anorectal malformation, and presacral mass.
Comparative effects of non-pharmacological intervention categories on cognitive domains in children with autism spectrum disorder: A systematic review and network meta-analysis of randomized controlled trials.
This systematic review and network meta-analysis compared non-pharmacological intervention categories for cognitive outcomes in children with autism spectrum disorder, drawing on randomized controlled trials.
Hemi-see-saw nystagmus with superimposed pendular oculopalatal tremor: case report and systematic review.
A 30-year-old man with a pontomedullary arteriovenous malformation presented with pendular hemi-see-saw nystagmus, right one-and-a-half syndrome, gaze-evoked nystagmus, ocular tilt reaction, incomplete Horner syndrome…
Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.
A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.
Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.
This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings.
Six-month supervised telerehabilitation combining pilates-based therapeutic exercise and self-myofascial release in adults with fibromyalgia: a randomized controlled trial.
This two-arm randomized controlled trial evaluated a six-month supervised home-based telerehabilitation programme in 68 adults with fibromyalgia confirmed by 2016 ACR criteria.
Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.
An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…
Haemodiafiltration, haemofiltration and haemodialysis for adults with kidney failure.
This Cochrane systematic review and meta-analysis assessed randomised trials comparing convective dialysis (haemofiltration, haemodiafiltration or acetate-free biofiltration) with diffusive haemodialysis or expanded…
Impact of a Dynamic Visualized Pain Assessment Tool on Pediatric Pain Management: A Stepped-Wedge Cluster Randomized Trial.
This stepped-wedge cluster randomized trial evaluated a dynamic visualized pain assessment tool across five clinical wards, involving 15 infants and 45 video segments spanning baseline, procedural pain, and…
Adenotonsillectomy for children with mild sleep-disordered breathing: who benefits?
This secondary analysis of a 12-month, multicentre randomised trial examined children aged 3.0–12.9 years with mild sleep-disordered breathing, comparing early adenotonsillectomy (eAT) with watchful waiting and…
Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence and determinants of post-stroke depression (PSD) in Ethiopia, combining findings from eight studies.
Clinical translation of polymeric microneedles for bioactive nanovesicle delivery in hypertrophic scar remodeling.
This prospective, single-center, open-label, single-arm study evaluated a 12-week protocol combining microplasma radiofrequency, poly(L-lactic acid) microneedles, and topical milk-derived bioactive nanovesicles in 26…
Refining Home-Based Squat Training: The Role of Hip Adduction in Improving Neuromuscular Control for Clinically Diagnosed Patellofemoral Pain Syndrome.
This randomized controlled trial compared an 8-week home-based squat program with and without hip adduction in 30 participants with clinically diagnosed patellofemoral pain syndrome (PFPS); both groups also performed…
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