Trending archive
Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.
2000 articles
October 202624
A Phase II Multicenter Trial of Rucaparib and Nivolumab as Maintenance Therapy in Patients with Advanced Biliary Tract Cancer: BilT-02.
BilT-02 was a multicenter phase II trial of rucaparib plus nivolumab as maintenance therapy for patients with advanced biliary tract cancer whose disease had not progressed after 4 to 6 months of first-line…
Body weight following a multidomain lifestyle intervention in older adults at risk of dementia - A post-hoc analysis of the AgeWell.de-trial.
This post-hoc analysis of the cluster-randomized AgeWell.de trial examined body weight in 678 adults aged 60–77 years with overweight or obesity and at risk for dementia.
Safety and efficacy of psilocybin-assisted therapy for alcohol use disorder: Open-label extension of a phase II randomized controlled trial.
This open-label extension of a phase II randomized controlled trial assessed safety and outcomes after one psilocybin-assisted therapy session in 59 adults with alcohol use disorder.
Ponatinib-Blinatumomab or Imatinib-Chemotherapy for Adult Ph-Positive ALL.
This multicenter, phase 3 randomized trial compared frontline ponatinib plus blinatumomab with imatinib plus chemotherapy in adults with Philadelphia-positive acute lymphoblastic leukemia.
Phase 2 Trial of Icotrokinra for Patients with Ulcerative Colitis.
This phase 2b, double-blind, randomized trial evaluated once-daily oral icotrokinra, an interleukin-23 receptor blocker, in adults with moderately to severely active ulcerative colitis.
Geographic Variation in Diagnostic Performance of Amsel Criteria and Nugent Score for Vaginal Dysbiosis Defined by 16S rRNA Gene Sequencing.
This analysis compared Amsel criteria and Nugent scoring with 16S rRNA sequencing-defined vaginal community state types in screening and follow-up specimens from a Phase 1b randomized trial at sites in South Africa and…
Effects of stellate ganglion blockade on pulmonary artery pressure and sympathetic baroreflex function at high altitude: a case study in treated hypertension.
A 44-year-old man with treated hypertension underwent physiological assessment at sea level and after 5–8 days at 3,800 m. High-altitude exposure was accompanied by increases in pulmonary artery systolic pressure…
Immunogenicity of a Bivalent Typhoid-Paratyphoid Conjugate Vaccine Against Diverse Salmonella Paratyphi A Isolates.
This exploratory analysis of a phase 1 randomised controlled trial assessed O:2-specific IgA and IgM responses and serum bactericidal activity after two doses of a bivalent typhoid-paratyphoid conjugate vaccine.
Long-Acting HIV Therapy in African Adults with Adherence Challenges.
This phase 3b, open-label, randomized trial compared long-acting injectable cabotegravir plus rilpivirine with daily oral dolutegravir-based therapy in adults in Kenya, South Africa, and Uganda who had suppressed HIV-1…
Key Predictors of Cerebral Vasospasm Following Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined observational evidence on factors associated with cerebral vasospasm after subarachnoid hemorrhage (SAH).
Optimization of Anticoagulation Strategy During Cardiopulmonary Bypass in Neonates with Congenital Heart Disease: A Randomized Controlled Trial.
Neonatal hemostatic immaturity complicates anticoagulation during cardiopulmonary bypass (CPB). Current practice largely follows the strategy of 400 U/kg from adult protocols, as neonatal-specific guidelines and…
Focal Epithelial Hyperplasia in a Somali Child: A Case Report and Review of Management with Topical Imiquimod.
An 8-year-old Somali girl had a 3.5-year history of asymptomatic, progressively increasing oral lesions. Examination showed multiple soft, flat-topped verrucous papules on the lower labial, buccal and lingual mucosa and…
Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis.
This systematic review and meta-analysis of 16 randomized controlled trials involving 994 patients assessed anterior quadratus lumborum block (aQLB) for postoperative analgesia after hip surgery.
Serum Virus-Neutralizing Antibody Titers in Clinical Trial Participants With and Without Immunocompromise Receiving Pemivibart, a Long-Acting Monoclonal Antibody for COVID-19.
This analysis of phase 3 CANOPY and phase 1 trial data examined measured and calculated serum virus-neutralizing antibody titers after pemivibart in participants with and without significant immunocompromise.
A Prospective, Multicenter, Evaluator-Blind, Randomized, Comparator-Controlled Study of Belotero Intense (+), a Hyaluronic Acid Filler With Lidocaine, for Lip Augmentation.
This multicenter, evaluator-blind randomized comparator-controlled equivalence trial assessed Belotero Intense with lidocaine (BIL) for lip augmentation in patients with lip volume deficits, comparing it with Restylane…
A phase 2 trial of daratumumab monotherapy for patients with newly diagnosed cardiac stage IIIb AL amyloidosis.
This prospective, multicentre phase 2 trial evaluated daratumumab monotherapy in previously untreated patients with measurable AL amyloidosis and advanced cardiac stage IIIB disease; patients with inadequate response…
TRANSFORM-1 phase 3 study: efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis.
TRANSFORM-1 was a multicentre, randomised phase 3 trial comparing navitoclax plus ruxolitinib with placebo plus ruxolitinib in Janus kinase inhibitor-naïve adults with intermediate-2 or high-risk myelofibrosis.
Artificial intelligence EEG biomarkers for schizophrenia diagnosis: Systematic review with PROBAST+AI assessment.
This systematic review assessed the diagnostic performance and methodological quality of AI models using resting-state EEG to identify schizophrenia or first-episode psychosis.
Micro-layering technique for esthetic rehabilitation. A case report.
A male patient sought esthetic rehabilitation for a diastema between the central incisors, mismatched tooth shapes, and overall dental disharmony.
A Systematic Review of Screen Time and Obesity in Children, Adolescents, and Young Adults: Sex-Specific Pathways and Implications for Public Health Interventions.
This systematic review synthesized evidence on screen time and obesity-related outcomes in children, adolescents, and young adults, examining possible sex-specific patterns.
Comparison of fecal continence and bowel function scoring systems following anorectal malformation repair: a systematic review.
This systematic review assessed whether fecal continence and bowel function scoring systems give comparable results when applied to the same cohorts after anorectal malformation repair.
3D-printed reduction guide with hinge and window. Design for conservative veneer preparations.
A 36-year-old woman sought improvement of her smile. Existing ceramic veneers from the maxillary right to left canine showed staining and crack lines, with mild gingival recession around the restored teeth.
A Phase I Dose-Escalation/Expansion Study of Fractionated-Dose and Multiple-Cycle Anti-PSMA-Targeted α-Emitter 225Ac-J591 in Patients with Prostate Cancer.
This phase I dose-escalation and expansion study evaluated fractionated and repeated-cycle 225Ac-J591 in patients with progressive metastatic prostate cancer resistant to androgen pathway modulation.
Uniportal versus Multiportal Video-Assisted Thoracoscopic Surgery for Minimally Invasive Esophagectomy in Esophageal Cancer: A GRADE-Assessed Systematic Review and Meta-Analysis.
This GRADE-assessed systematic review and meta-analysis compared uniportal (uVATS) with multiportal video-assisted thoracoscopic surgery (mVATS) for minimally invasive esophagectomy in adults with esophageal cancer.
Showing the most recent matches. Add a word or a date to reach older ones.
Stay updated for free
Get the 3 most interesting publications in one specialty each week.
Weekly email. Unsubscribe anytime.
Want this personalized?
Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.
- Your specialties
- Your filters and thresholds
- Clinical Research + Case Reports, tuned separately
- Automatic weekly delivery
- Audio and text
Prefer listening? Personalized audio digests are available with Pro.