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2000 articles

October 202624

Case ReportHematology

Iptacopan combined with immunosuppressive therapy for aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome: A case report.

A previously healthy 24-year-old man presented with dizziness, fatigue, and pancytopenia. Bone marrow examination supported aplastic anemia, with a PNH clone also identified.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportNeurosurgery

Bilateral lower limb dysfunction due to acute hematoma in the lumbar ligamentum flavum: A case report and literature review.

A 71-year-old man developed sudden lower back pain without an identifiable trigger, followed by worsening pain, numbness, and weakness in both legs.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Lymphoplasmacytic Lymphoma Involving Marrow-Containing Submandibular Heterotopic Ossification: A Case Report and Literature Review.

A 77-year-old man presented with a gradually enlarging, increasingly uncomfortable calcified nodule in the left submandibular region.

Head Neck PatholOct 16, 2026Read case
Clinical ResearchCardiology

Global Prevalence of Adherence to Antihypertensives and Associated Moderating Factors Among Adults With Hypertension: A Meta-Analysis.

This systematic review and meta-analysis estimated global adherence to antihypertensive medication among adults with hypertension.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Acute management of pelvic ring injuries: identifying common treatment principles across institutional algorithms.

This PRISMA-guided systematic review compared published institutional algorithms for acute pelvic ring injury management. Searches identified 25 studies describing algorithms, pathways, or protocols published from 2006…

Eur J Orthop Surg TraumatolOct 16, 2026Read summary
Case ReportAnesthesiology

Individualized multimodal pain management for chronic perineal pain: A case report.

A 68-year-old woman had three years of chronic perineal pain and tenderness that disrupted sleep, urination, and daily activities.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchOncology (Medical)

Three traditional Chinese patent medicines combined with transarterial chemoembolization for primary liver cancer: A systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis assessed three traditional Chinese patent medicines combined with transarterial chemoembolization (TACE) for primary liver cancer.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchCardiology

Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.

This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchCardiology

Effectiveness of Discrete Strategies and Implementation Bundles for Improving Clinician Prescription of Clinical Practice Guideline-Recommended Medications for Atherosclerotic Occlusive Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed randomized trials of strategies to improve prescription of guideline-strongly-recommended medications for adults with atherosclerotic occlusive disease.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchCardiology

Psychological Stress and the Diurnal Patterns of Sodium Excretion and Blood Pressure: Results From the SABRE Study.

The SABRE study examined whether urinary sodium responses to mental stress were associated with day–night sodium excretion patterns and systolic blood pressure (BP) dipping in apparently healthy adults.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchUrologyOpen access

Preoperative ureteral rest and outcomes of robot-assisted upper urinary tract reconstruction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether preoperative ureteral rest is associated with outcomes after robot-assisted ureteral reconstruction or pyeloplasty.

J Robot SurgOct 16, 2026Read summary
Case ReportNephrology

Complete remission of minimal change disease after antiviral monotherapy in a patient with immune-active chronic hepatitis B: A case report.

A 42-year-old woman presented with generalized edema, weight gain, hypoalbuminemia, and nephrotic-range proteinuria, with a urine protein-to-creatinine ratio of 4.3 and preserved renal function.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportNeurology

Spontaneous gene mutation encounters a paternal genetic variant: Nemaline myopathy: a case report and literature review.

A 21-year-old man had progressive weakness beginning in the distal lower limbs at age 3, later affecting proximal and masticatory muscles.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Safety and efficacy of a novel miniaturized robotic assisted surgery system in hysterectomy: a prospective, investigational device exemption clinical trial.

This prospective, multicentre, non-randomised Investigational Device Exemption trial assessed the safety and effectiveness of the MIRA miniaturized robotic system for benign hysterectomy.

J Robot SurgOct 16, 2026Read summary
Clinical ResearchGeriatrics

Planned Antihypertensive Deprescribing in Long-Term Care Residents: A Systematic Review of Randomized Evidence.

This systematic review synthesized randomized and cluster-randomized studies of planned antihypertensive deprescribing among long-term care residents.

Drugs AgingOct 16, 2026Read summary
Case ReportOncology (Medical)Open access

Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.

A 56-year-old patient with metastatic urothelial carcinoma developed extravasation of enfortumab vedotin and pembrolizumab during the first treatment cycle after the port catheter dislocated from the cephalic vein.

J Cancer Res Clin OncolOct 16, 2026Read case
Case ReportAnesthesiology

Multiple Recurarization Episodes After Sugammadex Reversal in Hyperthermic Intraperitoneal Chemotherapy: A Case Report.

A 53-year-old woman undergoing hyperthermic intraperitoneal chemotherapy (HIPEC) experienced three sequential episodes of recurarization after reversal of rocuronium-induced neuromuscular blockade with sugammadex 5.4…

A A PractOct 16, 2026Read case
Case ReportNeurology

Presumed oxaliplatin-related Guillain-Barré syndrome: A case report and review of chemotherapy-related Guillain-Barré syndrome.

A 77-year-old woman with metastatic cholangiocarcinoma and colorectal carcinoma developed rapidly progressive, symmetric ascending motor weakness about 2 weeks after her last cycle of gemcitabine, oxaliplatin…

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Effectiveness of different autologous platelet concentrates for orthodontic canine retraction following premolar extraction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich fibrin (L-PRF) for accelerating orthodontic canine retraction after…

Prog OrthodOct 16, 2026Read summary
Clinical ResearchEndocrinology

Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.

This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…

J Clin Endocrinol MetabOct 16, 2026Read summary
Case ReportPulmonology

Influenza A (H1N1) virus infection complicated by checkpoint inhibitor pneumonitis: A case report.

After neoadjuvant immunotherapy, a patient developed respiratory dysfunction and progressive pulmonary lesions. Imaging and positive influenza A (H1N1) testing, interpreted alongside the immunotherapy history and…

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchNephrology

Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.

This mixed methods study evaluated recruitment, engagement, completion, and participant experiences in Dialysafe, a digital education and peer-mentoring intervention at 10 hemodialysis centers.

J Med Internet ResOct 16, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)Open access

SOX10 Expression in Primary Salivary Gland Tumors: A Meta-Analysis.

This PRISMA-guided systematic review and meta-analysis assessed SOX10 immunohistochemical expression across primary salivary gland tumors. It included 35 studies comprising 1146 histological and 35 cytological samples.

Head Neck PatholOct 16, 2026Read summary
Case ReportNeurologyOpen access

A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy.

An Iranian girl presented with developmental delay, hypotonia, and refractory seizures. Whole-exome sequencing identified a de novo CDKL5 frameshift variant, c.1037_1038delTCinsCAGATCTAA (p.Ile346Thrfs*14), which Sanger…

Mol Biol RepOct 16, 2026Read case

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