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2000 articles

October 202624

Clinical ResearchObstetrics & GynecologyOpen access

Combined transcutaneous electrical nerve stimulation and low-level laser photobiomodulation for postoperative pain after cesarean section: A randomized controlled trial.

This randomized controlled trial compared combined transcutaneous electrical nerve stimulation (TENS) and low-level laser photobiomodulation (PBM) with TENS alone, placebo, and control for postoperative recovery after…

PLoS OneOct 22, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

The effect of telephone-based education and counselling on stoma adjustment and complication severity in individuals with a colostomy: a randomised controlled trial.

This randomised controlled trial evaluated telephone-based education and counselling for people with a colostomy, compared with routine stoma care.

Support Care CancerOct 22, 2026Read summary
Clinical ResearchNeurosurgery

Patterns and predictive factors of hearing loss following microvascular decompression for hemifacial spasm: a systematic review.

This systematic review and meta-analysis assessed the prevalence, patterns, and potential risk factors for hearing loss after microvascular decompression for hemifacial spasm.

Neurosurg RevOct 22, 2026Read summary
Clinical ResearchDermatologyOpen access

Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.

This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.

Lasers Med SciOct 22, 2026Read summary
Clinical ResearchHematologyOpen access

Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.

The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.

Blood Cancer JOct 22, 2026Read summary
Clinical ResearchOncology (Medical)

Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.

The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.

BloodOct 22, 2026Read summary
Clinical ResearchPediatricsOpen access

Clinical and radiographic success of bioflex versus stainless steel crowns using the hall technique in primary molars: a 12-month randomized controlled trial.

This two-arm randomized controlled trial compared BioFlex crowns (BFCs) with stainless-steel crowns (SSCs), both placed using the Hall Technique, in healthy children aged 4–6 years with carious mandibular second primary…

Clin Oral InvestigOct 22, 2026Read summary
Clinical ResearchPulmonology

Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.

Med Sci MonitOct 22, 2026Read summary
Case ReportNeurology

Tuberculosis-Associated Longitudinally Extensive Transverse Myelitis.

A 51-year-old man with a year of chronic non-productive cough and about 20 days of fever and headache presented with encephalopathy but no focal neurological deficits.

Am J Case RepOct 22, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

The Variability in the Pharmacokinetics of Follitropin Alfa: A Systematic Review.

This systematic review synthesised human studies of pharmacokinetic variability in follitropin alfa. Fifteen eligible studies were evaluated.

Clin PharmacokinetOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.

This randomised study in a general-population panel in Great Britain examined whether administration order affects comparisons of the EQ-5D-3L and EQ-5D-5L.

Qual Life ResOct 22, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Maternal and Neonatal Complications in Pregnant Women With Polyendocrine Metabolic Ovarian Syndrome: A Nested Prospective Cohort Study.

This prospective nested cohort study examined associations between polyendocrine metabolic ovarian syndrome (PMOS) and pregnancy outcomes among 3,645 pregnant women with risk factors for hyperglycemia enrolled in an…

Diabetes CareOct 22, 2026Read summary
Clinical ResearchGeriatrics

Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.

This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…

PsychogeriatricsOct 22, 2026Read summary
Clinical ResearchPulmonologyOpen access

Phase 3 Antifibrotic-Directed Therapy Outcomes in Idiopathic Pulmonary Fibrosis: Beyond FVC Decline.

This systematic review compared phase 3 randomized, placebo-controlled trials of antifibrotic-directed therapies in idiopathic pulmonary fibrosis (IPF), examining FVC decline, treatment discontinuation, and mortality.

LungOct 22, 2026Read summary
Clinical ResearchPulmonology

Independent and interactive effects of traffic-related noise and air pollution on lung function: A randomized crossover study in healthy young adults.

This randomized crossover study examined independent and interactive effects of traffic noise and air pollution on lung function in 51 healthy adults exposed beside a busy urban road during evening rush hour.

Environ ResOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Locus coeruleus abnormalities on neuromelanin-sensitive MRI in Parkinson's disease: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed locus coeruleus (LC) integrity on neuromelanin-sensitive MRI in Parkinson’s disease (PD), pooling independent comparisons with healthy controls using random-effects…

J NeurolOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Disentangling direct and weight-mediated effects of physical activity on health-related quality of life in a 12-month real-world digital lifestyle intervention.

This longitudinal study examined physical activity and health-related quality of life (HRQoL) among 1,732 people participating in a 12-month digital lifestyle program; the abstract identifies it as a clinical trial but…

Qual Life ResOct 22, 2026Read summary
Case ReportPediatrics

Hyponatremic-Hypertensive Syndrome as a Rare Manifestation of Renovascular Hypertension: A Case Series.

Two girls, aged 4 and 9 years, presented with severe hypertension and electrolyte disturbances, including hyponatremia and hypokalemia, with elevated renin-aldosterone activity.

Am J Case RepOct 22, 2026Read case
Clinical ResearchPreventive Medicine / Public Health

Combined Chatbot and Counselor Support for Smoking Cessation in China: A Pilot, Mobile-Based, Randomized Controlled Trial.

This two-arm, community-based randomized pilot trial in China assessed chatbot-supported smoking cessation and whether adding personalized counselor support might improve outcomes.

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Avatar-led digital health intervention for sexual and gender minority young adult smoking cessation: randomized controlled pilot trial.

This randomized controlled pilot trial compared EQQUAL, an Acceptance and Commitment Therapy-based digital smoking cessation program tailored for sexual and gender minority (SGM) young adults, with Smokefree.gov.

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchPulmonologyOpen access

A self-controlled case series to evaluate the effects of clinical trial eligibility criteria on biologic-associated reductions in severe asthma exacerbations: an analysis of the CHRONICLE study.

This study examined whether eligibility criteria used in biologic trials identify adults with severe asthma who are more likely to benefit.

Eur Respir JOct 22, 2026Read summary
Clinical ResearchPsychiatryOpen access

Randomized controlled trial of a group-based smoking cessation intervention for adults with serious mental illness.

This randomized controlled trial evaluated PARQuit in 99 adults with serious mental illness in the United States. Participants received 12 weeks of cessation counseling and pharmacotherapy and were assigned to…

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchPediatrics

Silver diamine fluoride versus conventional restorative treatment for dental caries in primary teeth of children: a meta-analysis.

This meta-analysis compared 30% to 38% silver diamine fluoride (SDF) with conventional restorative approaches for caries control in children with carious primary teeth.

Quintessence IntOct 22, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effects of transcranial direct current stimulation on nicotine use disorder: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed transcranial direct current stimulation (tDCS) for smoking-related outcomes in people with nicotine use disorder.

Nicotine Tob ResOct 22, 2026Read summary

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