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2000 articles

October 202624

Clinical ResearchDermatology

Balancing safety and efficacy in photodynamic therapy for facial port-wine stains in children aged 2-7 years: a prospective controlled study of light-intensity optimization.

This open-label, prospective controlled study compared two light intensities for hemoporfin-mediated photodynamic therapy in children aged 2–7 years with facial port-wine stains.

J Dermatolog TreatOct 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Lesion Water Content on CT Predicts 12-Month Outcome and Modifies Thrombectomy Effect in Large-Core Stroke-A Secondary Analysis of the TENSION Trial.

This secondary analysis of the randomized TENSION trial examined whether CT-derived net water uptake (NWU) predicts 12-month outcomes and modifies thrombectomy effects in 198 patients with large-core ischemic stroke.

Transl Stroke ResOct 23, 2026Read summary
Case ReportObstetrics & GynecologyOpen access

Primary tubal choriocarcinoma with extrauterine implantation masquerading as ectopic pregnancy: A case report and literature review.

A 29-year-old woman with irregular menses had extremely high β-human chorionic gonadotropin levels and ultrasonographic findings suggestive of ectopic pregnancy.

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportMedical GeneticsOpen access

Delayed diagnosis of MEN1 after kidney transplantation: unrecognized pre-transplant features and implications for clinical practice.

A 68-year-old man with end-stage renal disease underwent living-donor kidney transplantation and had persistent hypercalcemia afterward.

CEN Case RepOct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Comparative efficacy of common adjuvant treatments after resection of colorectal liver metastases: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared adjuvant strategies after resection of colorectal liver metastases, including systemic chemotherapy, hepatic arterial infusion chemotherapy (HAIC), and…

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportPlastic SurgeryOpen access

Staged limb salvage after an infected full-thickness shoulder-girdle flame burn with osteoarticular exposure in an elderly patient: A case report with 3.5-year follow-up.

A 73-year-old woman with diabetes, hypertension, and cachexia presented about 3 weeks after a flame burn with an extensive infected wound from the neck base to the distal left arm.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

The role of sexual mindfulness in enhancing sexual well-being among breast cancer survivors: A randomized clinical trial.

This randomized clinical trial assessed sexual mindfulness training for sexual well-being among women with breast cancer attending health service centers in Shahrekord, Iran.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportOncology (Medical)Open access

Primary renal diffuse large B cell lymphoma misdiagnosed as renal cell carcinoma: A case report.

A 78-year-old man presented with 2 weeks of right flank pain radiating to the abdomen; examination was unremarkable. Tests showed mildly elevated lactate dehydrogenase and occult blood in the urine.

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportPediatricsOpen access

Neonatal nemaline myopathy associated with NEB variants and a favorable 3-year outcome: A case report.

A female neonate developed cyanosis, bradycardia, respiratory distress, and hypotonia shortly after birth, with recurrent respiratory deterioration and bulbar feeding and swallowing difficulties.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchGeriatrics

Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.

This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…

JMIR AgingOct 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Minocycline in acute stroke: A systematic review and meta-analysis of randomized controlled trials and trial sequential analysis.

This systematic review and meta-analysis pooled randomized controlled trials comparing minocycline with control or standard care in acute ischemic and hemorrhagic stroke.

Medicine (Baltimore)Oct 23, 2026Read summary
Clinical ResearchGeriatricsOpen access

Systematic review and meta-analysis of risk factors for oral frailty.

This systematic review and meta-analysis examined factors associated with oral frailty across 14 studies involving 12,297 participants, of whom 4,540 had oral frailty.

Medicine (Baltimore)Oct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.

J Med Internet ResOct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Precancerous cervical lesions and associated factors among HIV-positive women in Southern and Eastern African countries: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled evidence on precancerous cervical lesions (PCCL) and associated factors among women living with HIV in Southern and Eastern Africa.

PLoS OneOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…

Cancer Chemother PharmacolOct 23, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

A case report of pulmonary embolism following endoscopic cervical discectomy in an elderly patient with cervical disc herniation.

A 65-year-old woman with cervical disc herniation, right arm pain, and multiple comorbidities underwent posterior percutaneous endoscopic cervical discectomy after conservative treatment failed.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchNeurology

Outcomes of Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke Due to Cardioembolism: A Secondary Analysis of the POST-UK Trial.

This secondary analysis of the multicenter, randomized POST-UK trial assessed adjunctive intra-arterial urokinase after near-complete to complete reperfusion in patients with acute ischemic stroke due to cardioembolism.

J Am Heart AssocOct 23, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Skeletal effects of GLP-1 receptor agonist therapy in adults with overweight or obesity: a systematic review.

This systematic review examined randomized evidence on bone mineral density (BMD) and bone-turnover markers in adults with overweight or obesity receiving GLP-1 receptor agonists.

Arch OsteoporosOct 23, 2026Read summary
Case ReportNeurologyOpen access

Spontaneous regression of post-traumatic syringomyelia: longitudinal mr imaging demonstrating a dynamic disease course.

A 69-year-old patient with post-traumatic cervicothoracic syringomyelia presented with occipital headaches, dizziness, and subjective upper-extremity weakness.

Spinal Cord Ser CasesOct 23, 2026Read case
Case ReportOrthopedic SurgeryOpen access

Integrated tendon repair and staged skin grafting for a severe forearm degloving injury: A case report from a low-resource setting.

A 21-year-old right-handed man presented two hours after a road traffic collision with extensive degloving of the right forearm, wrist, and dorsal thumb.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.

This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…

Nat CommunOct 23, 2026Read summary
Clinical ResearchGastroenterology

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.

This double-blind randomised controlled substudy examined YAQ001’s effects on the gut microbiome and exploratory markers of gut permeability and systemic inflammation in 28 patients with cirrhosis.

Liver IntOct 23, 2026Read summary
Clinical ResearchDermatologyOpen access

Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.

This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.

Lasers Med SciOct 23, 2026Read summary
Case ReportNeurology

Intermittent Maple Syrup Urine Disease Presenting With Chronic Demyelinating Polyneuropathy: A Genetically Confirmed DBT-Related Case.

A female patient with intermittent maple syrup urine disease (MSUD), genetically confirmed by compound heterozygous pathogenic DBT variants, had recurrent ataxic episodes from early childhood.

J Peripher Nerv SystOct 23, 2026Read case

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