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2000 articles
October 202624
Abscopal-like Regression of Lung Metastases After Near-infrared Photoimmunotherapy Plus Nivolumab in Laryngeal Carcinoma.
A man in his 60s with recurrent laryngeal squamous cell carcinoma, base-of-tongue involvement, and multiple pulmonary metastases had progressed after several treatments, including platinum- and pembrolizumab-containing…
TENON CAPSULE GRAFT AS A SEALANT IN PEDIATRIC RETINAL DETACHMENT.
The report describes four pediatric cases of complex retinal detachment associated with infantile high-myopic macular holes, Morning Glory Syndrome, or optic disk pit maculopathy.
Therapeutic plasma exchange improves survival in alcohol-related acute-on-chronic liver failure: a randomized controlled trial.
This randomized controlled trial evaluated therapeutic plasma exchange (PLEX) plus standard medical therapy versus standard therapy alone in 100 patients with alcohol-related acute-on-chronic liver failure.
IDIOPATHIC ACUTE EXUDATIVE POLYMORPHOUS VITELLIFORM MACULOPATHY: A 5-YEAR FOLLOW-UP.
A patient with idiopathic acute exudative polymorphic vitelliform maculopathy had 20/20 visual acuity in both eyes. Examination showed symmetrical multifocal serous retinal detachments and foveal vitelliform lesions…
Cranial and Spinal Epithelioid Hemangioma: Systematic Review and Illustrative Calvarial Case.
Cranial and neuraxial epithelioid hemangioma (EH) is exceptionally rare and anatomically heterogeneous. We systematically reviewed reported cerebral, cranial osseous, primary non-osseous spinal epidural, and…
Impact of acoramidis on clinical stability in transthyretin amyloid cardiomyopathy: observations from ATTRibute-CM.
This post-hoc analysis of the phase 3, multicentre, randomised ATTRibute-CM trial assessed clinically meaningful changes in NT-proBNP or 6-minute walk distance among participants with transthyretin amyloid…
Rapid-Onset Subacute Combined Degeneration After Short-Term, High-Dose Nitrous Oxide Use.
The title identifies a case of rapid-onset subacute combined degeneration (SCD) after short-term, high-dose recreational nitrous oxide use.
Neck-Specific Exercises With Internet Support Versus Standard Neck-Specific Exercise for the Treatment of Chronic Whiplash-Associated Disorders: Cost-Effectiveness Analysis.
This prospective, multicenter randomized controlled trial compared a 3-month internet-supported neck-specific exercise program plus four physiotherapy visits (NSEIT) with clinic-based neck-specific exercise twice weekly…
Unmasking Weakness: A Case of Pembrolizumab-induced Myasthenia Gravis With Concurrent Myositis.
An 86-year-old patient with renal cell carcinoma developed generalized weakness, dysphagia, dysphonia, eyelid ptosis, and ophthalmoparesis shortly after the second dose of pembrolizumab.
Pars plana vitrectomy with silicone oil versus pars plana vitrectomy alone for postoperative endophthalmitis: A randomized controlled trial.
This prospective randomized controlled trial compared pars plana vitrectomy (PPV) with 1000-cSt silicone oil (SO) tamponade against PPV alone in 40 eyes with severe post-phacoemulsification endophthalmitis unresponsive…
Efficacy of a Gamified Training Program for Improving Occupational Health and Safety Knowledge Among Italian Secondary School Students: A Randomized Controlled Field Trial.
This cluster-randomized controlled field trial assessed whether a gamified occupational health and safety (OHS) program improved knowledge among Italian secondary school students.
Parathyroid Hormone-related Peptide Is a Better Indicator of Cancer Treatment Efficacy Than Serum Calcium.
A 66-year-old woman with extensive cutaneous squamous cell carcinoma of the scalp, unsuitable for primary surgical removal, received cemiplimab.
SUBRETINAL LAVAGE DURING DIAGNOSTIC VITRECTOMY: AN ADJUNCTIVE TECHNIQUE FOR CELL SAMPLING IN SUSPECTED VITREORETINAL LYMPHOMA.
In patients with suspected vitreoretinal lymphoma and predominant subretinal involvement, standard vitreous sampling may have limited sensitivity.
Pearls & Oy-sters: Beyond the Bone Marrow-VEXAS Syndrome Presenting as Subacute Encephalomyelitis.
A 70-year-old man with myelodysplastic syndrome and confirmed VEXAS syndrome (UBA1 p.Met41Thr) developed subacute ascending paresthesia, Lhermitte sign, and urinary hesitancy.
An Elusive Diagnosis of Strongyloides Infection Masquerading as Daptomycin-Induced Eosinophilic Pneumonitis.
A middle-aged man with alcoholic cirrhosis developed peripheral eosinophilia, bilateral pulmonary nodules, migratory consolidative opacities, and pleural effusions while receiving daptomycin for polymicrobial…
Targeted BRAF /MEK inhibition as a salvage therapy for patients with metastatic melanoma harboring a BRAF L597R mutation: two case reports and review of the literature.
Two patients with metastatic melanoma harboring the BRAF L597R mutation had rapid clinical deterioration and disease progression after dual immune checkpoint inhibition.
Association between chronic opioid exposure and cardiovascular disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between chronic opioid exposure—including opium use, opioid use disorder, and prescription opioids—and cardiovascular disease in human studies.
Vascular health after quitting smoking or switching to e-cigarette use: a systematic review of prospective studies with GRADE assessment.
This systematic review assessed prospective evidence on vascular function after smoking cessation or switching to exclusive e-cigarette use among adult smokers.
Efficacy and safety of intralesional versus intracoronary administration of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention for acute coronary syndromes: a meta-analysis of randomized controlled trials.
This meta-analysis of nine randomized controlled trials compared intralesional with intracoronary glycoprotein IIb/IIIa inhibitor administration during PCI in patients with acute coronary syndromes.
TEN-YEAR FOLLOW-UP OF FLUID FLUCTUATIONS IN A PATIENT WITH OPTIC DISK PIT MACULOPATHY.
A patient with optic disk pit maculopathy had severe subretinal fluid involving the fovea and underwent pars plana vitrectomy. The fluid resolved for 2 years, then subretinal fluid recurred alongside intraretinal fluid.
PARS PLANA VITRECTOMY WITH FOVEAL CYST ASPIRATION AS A TREATMENT OPTION FOR MACULAR RETINOSCHISIS IN A COATS-LIKE RETINITIS PIGMENTOSA CASE.
A 45-year-old woman with CRB1 mutation-related retinitis pigmentosa was referred for surgery for macular detachment. Examination and imaging showed bilateral bullous macular retinoschisis associated with Coats-like…
SUCCESSFUL MANAGEMENT OF A GIANT MACULAR HOLE IN ALPORT SYNDROME USING AUTOLOGOUS RETINAL TRANSLATION AS AN INITIAL PROCEDURE.
A 30-year-old woman with Alport syndrome had bilateral anterior lenticonus and a giant full-thickness macular hole in her right eye, measuring 1,791 μm.
WHIPLASH MACULOPATHY: STRUCTURAL SEQUELAE AND THE CORRESPONDING VISUAL IMPAIRMENT, DOCUMENTED WITH OPTICAL COHERENCE TOMOGRAPHY.
A 55-year-old woman developed reduced vision in her left eye after a head-on collision. Examination showed subtle retinal pigment epithelium disruption; OCT demonstrated neurosensory detachment and intraretinal cysts.
INTRARETINAL SCLEROCHOROIDAL VESSELS IN EYES WITH SEVERE CHORIORETINAL THINNING: HYPOTHESIS ON BRUCH's MEMBRANE FAILURE.
A retrospective case series described six eyes with advanced chorioretinal thinning from varied causes, including pathologic myopia, iatrogenic staphyloma, chronic anti-VEGF exposure, and nonmyopic macular atrophy.
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