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2000 articles

October 202624

Clinical ResearchNeurologyOpen access

The effect of acupuncture-rehabilitation therapy on brain functional plasticity in motor aphasia after ischemic stroke: a randomized clinical neuroimaging trial.

This randomized clinical neuroimaging trial assigned 26 patients with motor aphasia after ischemic stroke to conventional rehabilitation (CR) or CR plus acupuncture-rehabilitation (A-R); 26 healthy controls provided…

Brain Imaging BehavOct 30, 2026Read summary
Case ReportPsychiatryOpen access

Lurasidone Induced Amphibian Like Buccal Oscillations: A Rare Case of Early Onset Tardive Dyskinesia Like Disorder in a Geriatric Patient with Treatment-Resistant Depression.

A 64-year-old woman with treatment-resistant depression developed floor-of-mouth movements resembling buccal pumping, along with white spots on the inner lower lip and facial puffiness, within 7 days of starting…

Psychopharmacol BullOct 30, 2026Read case
Case ReportDermatologyOpen access

Asymptomatic Tattoo-Associated Cutaneous Nontuberculous Mycobacterial Infection: Case Report.

An immunocompetent 28-year-old man presented with monomorphic papules bearing collarettes of scale, diffusely distributed but confined to recently tattooed skin.

JMIR DermatolOct 30, 2026Read case
Case ReportOrthopedic Surgery

Tibial Post Fracture in a Posterior-Stabilized Knee Prosthesis: A Case Report and Review of the Literature.

A 92-year-old man developed acute mechanical knee pain, recurrent clicking, and subjective instability 16 years after a previously well-functioning posterior-stabilized total knee arthroplasty, following a low-energy…

Am J Case RepOct 30, 2026Read case
Clinical ResearchInfectious Diseases

Predictors of chronic arthralgia after chikungunya virus infection: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of chronic arthralgia, defined as lasting at least 3 months, after laboratory-confirmed chikungunya infection.

J Travel MedOct 30, 2026Read summary
Clinical ResearchPediatrics

Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial.

PROSpect was an international, two-by-two factorial, phase 3 randomised controlled trial comparing prone with supine positioning and high-frequency oscillatory ventilation (HFOV) with conventional mechanical ventilation…

LancetOct 30, 2026Read summary
Clinical ResearchPulmonologyOpen access

The effect of propolis oral care on oral mucositis in intensive care patients with chronic obstructive pulmonary disease: a randomized controlled trial.

This randomized controlled trial evaluated whether adding propolis gargle to standard oral care prevented oral mucositis in 60 critically ill patients with chronic obstructive pulmonary disease.

Rev Assoc Med Bras (1992)Oct 30, 2026Read summary
Clinical ResearchCardiology

Efficacy of Stellate Ganglion Block for Preventing Postoperative Atrial Fibrillation After Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

This single-center, randomized, double-blind, placebo-controlled trial assessed whether preoperative ultrasound-guided right stellate ganglion block (SGB) prevents postoperative atrial fibrillation (POAF) in patients…

J Am Heart AssocOct 30, 2026Read summary
Clinical ResearchNephrology

Efficacy and Safety of Nafamostat Mesilate Injection in Patients Receiving Continuous Renal Replacement Therapy: A Meta-Analysis.

This meta-analysis assessed the efficacy and safety of nafamostat mesilate injection versus no anticoagulation in patients receiving continuous renal replacement therapy (CRRT).

J Vis ExpOct 30, 2026Read summary
Clinical ResearchPsychiatry

Effects of psilocybin with psychological support on anhedonia in treatment-resistant depression: A randomized controlled pilot trial.

This randomized, double-blind, placebo-controlled pilot trial assessed psilocybin with psychological support for anhedonia in 20 participants with treatment-resistant major depressive disorder.

J Affect DisordOct 30, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Associated factors for stress ulcers and gastrointestinal bleeding in patients with sepsis or septic shock: A systematic review.

This systematic review synthesized observational cohort and case-control studies of factors associated with stress ulcers or significant gastrointestinal bleeding in adults with sepsis or septic shock.

PLoS OneOct 30, 2026Read summary
Clinical ResearchNeurologyOpen access

First-in-Human Phase 1b/2a Trial Shows Safety with MEK 1/2 Inhibitor EDV2209 as A Novel Treatment for Spontaneous Subarachnoid Hemorrhage.

The STOP-DCI first-in-human Phase 1b/2a interventional, randomized, double-blind, placebo-controlled trial evaluated intracerebroventricular EDV2209, a MEK 1/2 inhibitor, in patients with severe spontaneous subarachnoid…

Transl Stroke ResOct 30, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Survival Outcomes in Metastatic Colorectal Cancer Patients with BRAF Mutations Undergoing Targeted Chemotherapy: A Reconstructed Individual Patient Data Meta-Analysis of Randomized Controlled Trials.

This reconstructed individual patient-data meta-analysis of 18 randomized controlled trials examined survival outcomes across targeted treatment classes in BRAF V600E-mutant metastatic colorectal cancer.

J Gastrointest CancerOct 30, 2026Read summary
Clinical ResearchDermatology

Integrated Traditional Chinese Medicine, Mili-Fire Needle, and Light-Emitting Diode Phototherapy for Cystic Acne and Post-Acne Sequelae.

This single-center, parallel-group randomized clinical study compared an integrated traditional Chinese medicine regimen, mili-fire needle therapy, and red-blue LED phototherapy with isotretinoin plus the same…

J Vis ExpOct 30, 2026Read summary
Clinical ResearchCardiology

Incidence of Intensive Care Unit Delirium After Heart Surgery: A Feasibility Study of a Forest Environment Intervention.

This randomized feasibility study evaluated forest-environment and light-exposure interventions, compared with standard care, in adults undergoing elective cardiac surgery at a tertiary ICU in Austria.

Nurs Crit CareOct 30, 2026Read summary
Case ReportUrology

Robotic-Assisted Partial Nephrectomy in a Solitary Kidney in a von Hippel-Lindau Renal Cell Carcinoma.

A 37-year-old man with von Hippel-Lindau disease and a solitary right kidney after left radical nephrectomy had three progressive clear cell renal cell carcinoma lesions, the largest 4.8 cm, despite belzutifan.

J Vis ExpOct 30, 2026Read case
Clinical ResearchInfectious Diseases

Endpoint-specific mortality associated with malignancy among adults with sepsis or septic shock: a systematic review and meta-analysis.

This systematic review and meta-analysis examined mortality among adults with sepsis or septic shock, comparing patients with and without malignancy.

Ann MedOct 30, 2026Read summary
Case ReportDermatologyOpen access

Atypical Fibroxanthoma Presenting as a Rapidly Enlarging Tender Papule: Case Report.

A 67-year-old woman with prior basal and squamous cell carcinomas presented with a rapidly enlarging, tender papule on the dorsal left hand that had not responded to topical 5-fluorouracil.

JMIR DermatolOct 30, 2026Read case
Clinical ResearchPsychiatryOpen access

Dose-Dependent Effect of Crocin on Depressive and Anxiety Symptom Scores: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This GRADE-assessed systematic review and meta-analysis examined dose-response associations between crocin supplementation and depressive and anxiety symptom scores in 14 randomized controlled trials.

Depress AnxietyOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

How do adult migrants with active TB adhere to care in high-income countries? A systematic review.

This systematic review examined adherence to the TB care process among adult migrants with active TB in high-income countries.

Int J Tuberc Lung DisOct 30, 2026Read summary
Clinical ResearchNephrology

Sexual dimorphism and age effects in CKD and type 2 diabetes in the CONFIDENCE trial.

This analysis of the randomized CONFIDENCE trial examined age- and sex-related differences in urinary albumin-to-creatinine ratio (UACR) changes among people with type 2 diabetes and chronic kidney disease receiving…

Nephrol Dial TransplantOct 30, 2026Read summary
Clinical ResearchCardiology

Acute declines in kidney function with thiazide plus loop diuretics versus loop diuretics alone in acute decompensated heart failure.

This analysis of the randomized CLOROTIC trial examined whether early eGFR changes were associated with outcomes in patients admitted with acute decompensated heart failure and randomized to thiazide or placebo…

Nephrol Dial TransplantOct 30, 2026Read summary
Case ReportNephrology

Haemodialysis in haemophilia B: a case report. Challenges and strategies from a nephrology perspective.

A 68-year-old man with severe haemophilia B and kidney failure required kidney replacement therapy. He received prophylactic Idelvion® (albutrepenonacog alfa), then underwent arteriovenous fistula creation and started…

J NephrolOct 30, 2026Read case
Clinical ResearchNephrology

Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.

J NephrolOct 30, 2026Read summary

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