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2000 articles

November 202624

Clinical ResearchEmergency Medicine

Performance of the i-Gel Versus King LT-D by Combat Medics Under Simulated Tactical Conditions: A Prospective Randomized Crossover Study.

This prospective randomized crossover study compared i-gel and King LT-D placement by active-duty combat medics after exertion while wearing full combat gear, using a high-fidelity manikin.

Mil MedNov 1, 2026Read summary
Clinical ResearchRheumatology

Do People With Tophaceous Gout Require More Allopurinol for Good Clinical Outcomes? Analysis of 2 Randomized Controlled Trials of Allopurinol Dose Escalation.

This analysis of individual participant data from two randomized allopurinol dose-escalation trials compared outcomes in people with gout with and without baseline tophi.

J RheumatolNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

LEgal Guidance for Cancer Patients and CAREgivers (LEGACY CARE): A Pilot Clinical Trial.

This single-arm pilot clinical trial evaluated the feasibility and acceptability of proactive legal care for patient-caregiver dyads affected by advanced-stage colorectal cancer.

PsychooncologyNov 1, 2026Read summary
Clinical ResearchPediatrics

Implementing Respiratory Illness Care Pathways in General Hospitals: A Cluster Randomized Trial.

This pragmatic, multicenter cluster-randomized trial evaluated implementation of inpatient pathways for asthma, pneumonia, and bronchiolitis in US general hospitals.

PediatricsNov 1, 2026Read summary
Clinical ResearchNeurology

Transcranial Pulse Stimulation in Parkinson's Disease: A Systematic Review.

This systematic review assessed clinical, neurophysiological, imaging, and safety outcomes of transcranial pulse stimulation (TPS) in adults with idiopathic Parkinson’s disease.

Brain BehavNov 1, 2026Read summary
Clinical ResearchPulmonology

Effects of CT-guided Radiofrequency Versus Microwave Ablation on Pulmonary Function in Individuals with Pulmonary Tumors: A Prospective Multicenter Randomized Trial.

This prospective, multicenter randomized trial compared short-term pulmonary function after CT-guided radiofrequency ablation (RFA) or microwave ablation (MWA) in 138 participants with pulmonary tumors.

Radiol Imaging CancerNov 1, 2026Read summary
Case ReportPediatrics

A Neonate With Excessive Weight Loss and Electrolyte Abnormalities.

A 7-day-old girl was hospitalized for excessive weight loss. Initial testing showed hyponatremia and hyperkalemia, prompting evaluation for endocrine, renal, and metabolic causes.

PediatricsNov 1, 2026Read case
Case ReportOphthalmology

Vogt-Koyanagi-Harada (VKH) Syndrome Mimicking Bilateral Optic Neuritis.

A 36-year-old man developed progressive bilateral visual loss over 5 days, with papillitis on fundus examination. Brain MRI and CSF were normal, and serum NMO and MOG testing was negative.

NeurologistNov 1, 2026Read case
Clinical ResearchGeriatrics

Effect of Exercise Interventions on Sarcopenia-Related Outcomes in Older Adults With Type 2 Diabetes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed structured exercise versus nonexercise control in adults with type 2 diabetes whose mean age was at least 65 years.

Geriatr Gerontol IntNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational cohort evidence on restarting immune checkpoint inhibitors (ICIs) after treatment interruption for an immune-related adverse event (irAE).

Cancer MedNov 1, 2026Read summary
Case ReportNeurology

Dizziness, Scanning Speech, and Transient Hyperreflexia as Atypical Initial Manifestations of Antiganglioside Q1b-Negative Miller Fisher Syndrome: A Case Report and Literature Review.

A 27-year-old Chinese Han man presented with prominent dizziness and scanning speech. Examination initially showed generalized tendon hyperreflexia, intention tremor, and a right Babinski sign.

Immun Inflamm DisNov 1, 2026Read case
Clinical ResearchPediatrics

Diagnosis and Management of Achalasia in Children, BSPGHAN and BAPS Consensus Statement.

This consensus statement addresses diagnosis and management of achalasia in children, for whom pediatric-specific guidelines were lacking.

Neurogastroenterol MotilNov 1, 2026Read summary
Clinical ResearchRheumatology

Effect of Bimekizumab Treatment on Health Status, Work Productivity, and Productivity Costs Through 3 Years in Axial Spondyloarthritis and Psoriatic Arthritis.

This analysis assessed health status, work productivity, and productivity-related costs through 3 years among patients with axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA) treated with bimekizumab in phase…

J RheumatolNov 1, 2026Read summary
Clinical ResearchDermatology

Five-year outcomes of the STOP-AD randomised controlled trial: Long-term effects of early emollient therapy in high-risk infants.

This blinded, single-centre, randomised controlled trial follow-up assessed whether brief neonatal emollient use was associated with lasting effects on atopic dermatitis (AD) in term infants at high risk of AD.

Pediatr Allergy ImmunolNov 1, 2026Read summary
Case ReportDermatology

Q-switched Nd:YAG Laser for Extrafacial Lichen Planus Pigmentosus: A Case Series Highlighting Outcomes and Risks.

Three patients with biopsy-proven lichen planus pigmentosus (LPP) involving facial and extrafacial sites received Q-switched neodymium:yttrium aluminum garnet laser treatment.

J Drugs DermatolNov 1, 2026Read case
Clinical ResearchRheumatology

Prevalence of Sleep Disorders in Patients With Knee, Hip, and Hand Osteoarthritis: A Systematic Review With Meta-Analysis.

This prevalence systematic review and meta-analysis assessed insomnia, obstructive sleep apnea, restless legs syndrome, and narcolepsy in people with knee, hip, or hand osteoarthritis.

J Orthop Sports Phys TherNov 1, 2026Read summary
Clinical ResearchPediatrics

Therapeutic Horseback Riding for Youth With Autism and Psychiatric Comorbidities: A Randomized Trial.

This multisite randomized controlled trial evaluated equine-assisted activities in youth aged 6–16 years with autism and psychiatric comorbidity.

PediatricsNov 1, 2026Read summary
Clinical ResearchDermatology

Peptides for Hair Growth and Treatment of Hair Loss and Alopecia: A Systematic Review.

This systematic review assessed clinical trials of peptide-containing therapies for hair loss in humans. Searches of PubMed, Embase, and the Cochrane Library identified 981 studies, of which 14 met the inclusion…

J Drugs DermatolNov 1, 2026Read summary
Clinical ResearchNephrologyOpen access

Transplantation of Hepatitis B Surface Antigen Positive or Viremic Kidneys: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed outcomes after transplantation of hepatitis B surface antigen-positive or viremic kidneys into non-viremic kidney transplant recipients.

Clin TransplantNov 1, 2026Read summary
Clinical ResearchEndocrinology

Severe Infection Outcomes With SGLT2 Versus DPP-4 Inhibitors in Type 2 Diabetes: A Systematic Review and Active-Comparator Meta-Analysis of Real-World Cohorts.

This systematic review and active-comparator meta-analysis examined real-world severe infection outcomes among people with type 2 diabetes treated with SGLT2 inhibitors versus DPP-4 inhibitors.

Endocrinol Diabetes MetabNov 1, 2026Read summary
Case ReportOrthopedic Surgery

A rare injury combination: Hawkins type I talar neck fracture, Jones fracture, and calcaneal avulsion fracture accompanying a bimalleolar ankle fracture.

A patient with a bimalleolar ankle fracture also had a Jones fracture, a Hawkins type I talar neck fracture, and a calcaneal avulsion fracture.

Ulus Travma Acil Cerrahi DergNov 1, 2026Read case
Case ReportPhysical Medicine & Rehabilitation

Upweighting Proprioceptive Information for Treatment of Mal de Mer: A Case Report.

A 46-year-old woman aboard a U.S. Navy ship developed severe dizziness that prevented unsupported walking and substantially limited computer work.

Mil MedNov 1, 2026Read case
Clinical ResearchRadiology (Diagnostic)

Added Value of Preoperative Contrast Enhanced Mammography in Staging of Malignant Breast Lesions (PROCEM): A Randomized Controlled Trial.

This prospective, multicenter randomized controlled trial evaluated whether preoperative contrast-enhanced mammography (CEM) adds value to standard imaging for staging early-stage breast cancer in women eligible for…

RadiologyNov 1, 2026Read summary
Clinical ResearchNuclear Medicine

Phase 2 Trial of 89 Zr-Deferoxamine-Daratumumab for CD38-targeted Immuno-PET/CT Detection of Multiple Myeloma.

This prospective phase 2 trial compared CD38-targeted 89Zr-DFO-daratumumab immuno-PET/CT with standard-of-care 18F-FDG PET/CT in 60 participants with multiple myeloma.

RadiologyNov 1, 2026Read summary

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