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2000 articles
November 202624
Proton-pump inhibitor-induced severe hypomagnesemia presenting with seizure and functional hypoparathyroidism: A diagnostic challenge in long-term acid suppression therapy.
A 68-year-old man taking omeprazole 40 mg/day for 8 years presented with a generalized tonic-clonic seizure and neuromuscular irritability.
Low-level laser therapy in ulcerative lesions in leprosy: a systematic review.
This systematic review assessed whether low-level laser therapy (LLLT) improves healing of ulcerative lesions in people with leprosy.
Acceptability of a patient support and educational intervention for black breast cancer survivors.
This clinical trial evaluated the feasibility and acceptability of a six-week group support and education intervention for English-speaking Black women who had survived stage I–III breast cancer diagnosed within the…
Dapagliflozin attenuates progression from prefrailty to frailty in patients with hypertension and chronic kidney disease.
DAPA-FORTRESS followed prefrail hypertensive adults aged over 65 years with chronic kidney disease (CKD) for 1 year to examine links between renal measures and physical performance, and whether dapagliflozin was…
Comparison of Traumatic Complications following Prostate Biopsy in Men with Lower Urinary Tract Symptoms Due to Prostate Disease Using Biopty Gun versus Semiautomatic Needle.
This randomised comparative study assessed pain and bleeding after digitally guided transrectal prostate biopsy using a semiautomatic needle or a fully automatic biopty gun in 64 men with lower urinary tract symptoms…
Danvatirsen plus Pembrolizumab versus Pembrolizumab for Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma (PEMDA-HN): A Randomized, Phase II Trial.
PEMDA-HN was a multicenter, open-label, randomized phase II trial comparing first-line danvatirsen plus pembrolizumab with pembrolizumab alone in patients with previously untreated, PD-L1-positive recurrent or…
Neoadjuvant PD-L1/TGF-β blockade can rapidly disrupt the tumor stroma in head and neck cancer patients.
This window-of-opportunity clinical study examined neoadjuvant bintrafusp alfa, a dual PD-L1 and TGF-β inhibitor, in patients with head and neck squamous cell carcinoma.
A Comparative Study of the Efficacy and Safety of Two Misoprostol Regimens for Labour Induction at Term in Delta State: A Two-centre Triple-blind Randomised Controlled Trial.
This two-centre, triple-blind randomised controlled trial compared hourly titrated oral misoprostol with four-hourly 25 mcg vaginal misoprostol for labour induction in 260 singleton term pregnancies in Delta State…
Sphenoidal Meningioma with Focal Seizures Masquerading as Immune Reconstitution Inflammatory Syndrome in HIV Patient.
A 47-year-old woman with HIV developed recurrent focal-onset seizures progressing to bilateral tonic-clonic seizures about 4 weeks after starting antiretroviral therapy.
Comparison of the opioid-sparing effects of a combination of dexamethasone, paracetamol, and ketorolac versus paracetamol and ketorolac in patients undergoing total laparoscopic hysterectomy: A prospective double-blind randomized controlled trial.
This prospective, double-blind randomized controlled trial compared adding intravenous dexamethasone to paracetamol and ketorolac with paracetamol and ketorolac alone in 100 women aged 18–60 years with ASA I–II status…
Early Metformin Initiation and Glycemic Outcomes in Gestational Diabetes: A Secondary Analysis of a Randomized Clinical Trial.
This secondary analysis of a double-masked, placebo-controlled randomized clinical trial assessed early metformin versus placebo, alongside usual care, in pregnancies complicated by gestational diabetes at two Irish…
Short-term bioavailability of EPA and DHA from an algae oil-fortified soymilk compared with algae oil capsules.
This 4-week, open-label, randomized parallel trial compared short-term EPA and DHA bioavailability from algae oil-fortified soymilk with algae oil capsules in 21 healthy adults.
An Exploratory Study of Image-Guided Cochlear Implant Intervention on Articulation and Phonological Processing in Children With Speech Sound Disorders.
This exploratory analysis examined articulation and phonological processing in 21 children aged 4.7–13.1 years with cochlear implants and deficits in these skills, enrolled in a 2-year waitlist-deferred randomized…
Effects of extremely low-volume high-intensity interval training combined with iron supplementation versus iron supplementation alone on postural control in young women with iron deficiency anemia: a randomized controlled trial.
This randomized controlled trial compared 8 weeks of extremely low-volume, plyometric-based high-intensity interval training (HIIT) plus oral iron with iron supplementation alone in young women aged 18–25 years with…
Full-Service Mobile Food Markets and Dietary Quality in Low-Income Housing Communities: A Randomized Clinical Trial.
This cluster randomized clinical trial evaluated weekly full-service mobile market service at 12 subsidized housing sites in the Minneapolis–St. Paul area.
Ethnoracial and Linguistic Diversity in Treatment Research for Primary Progressive Aphasia: A Systematic Review.
This systematic review examined ethnoracial, linguistic, and social-determinant representation in nonpharmacological intervention research for people with primary progressive aphasia (PPA) or primary progressive apraxia…
Effect of Blonanserin on Neurotrophic Factors in Patients With Non-Responsive First-Episode Schizophrenia Treated With Early Risperidone Monotherapy-A Randomized Controlled Trial.
This randomized controlled trial compared blonanserin with clozapine over 3 months in 120 hospitalized patients with first-episode schizophrenia who had not responded to early risperidone monotherapy.
Visual Perceptual Learning Based on Adaptive Contrast Detection Training Enhances Vision and Contrast Sensitivity in Diabetic Retinopathy.
This randomized controlled trial evaluated 3-month home-based visual perceptual learning (VPL) in people with diabetic retinopathy who had received routine therapies.
Breast Adenomyoepithelioma with Malignant Changes in a 36-year-old Female: Clinicopathological, Histomorphological and Therapeutic Considerations.
A woman described in the abstract as 360 years old presented with an asymptomatic left breast tumour measuring 2.5 cm × 2.0 cm × 0.8 cm.
RELAX Perinatal Digital Intervention to Prevent Increasing Anxiety: A Randomized Clinical Trial.
This multisite, phase 2b randomized clinical trial tested whether a self-led, pregnancy-tailored digital cognitive bias modification intervention added to usual maternity care could prevent rising anxiety in pregnant…
Randomized Single-Masked Study of Preservative-Free Versus Preserved Hyaluronic Acid in Dry Eye Disease.
This randomized, single-masked, 6-month trial compared preservative-free hyaluronic acid (PF HA) with benzalkonium chloride-preserved hyaluronic acid (BAK HA) in 47 patients with dry eye disease; 43 completed the study.
Drug-drug interactions between statins and antibiotics: A systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis assessed observational evidence on muscle toxicity when statins are used with interacting antibiotics, compared with statin therapy alone.
Multikinase Inhibition with Tinengotinib in Advanced Solid Tumors: Results from a Multicenter Phase Ib/II Trial.
This multicenter phase Ib/II trial evaluated tinengotinib’s safety, pharmacokinetics, antitumor activity, and genomic correlates in patients with advanced or metastatic solid tumors lacking standard treatment options.
Associations of Health Literacy and eHealth Literacy With Patient Portal Access and Use: Systematic Review.
This systematic review synthesized quantitative studies of health literacy and eHealth literacy in relation to real-world patient portal access and use among adults.
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