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2000 articles

November 202624

Case ReportOncology (Medical)

Dexmedetomidine with transition to oral clonidine for stabilization of refractory agitation: A case report.

A 45-year-old man with metastatic medullary thyroid carcinoma was admitted to a palliative care unit with severe opioid-refractory pain, delirium, and agitation that prevented palliative radiation.

Palliat Support CareNov 5, 2026Read case
Clinical ResearchOncology (Medical)Open access

Resistance training and protein supplementation in patients with incurable gastroesophageal cancer: a randomized feasibility trial.

This open-label, parallel-group randomized feasibility trial assessed resistance training plus protein supplementation during first-line chemotherapy in patients with incurable gastroesophageal cancer.

Support Care CancerNov 5, 2026Read summary
Case ReportCardiothoracic Surgery

Carotid artery bypass and supraclavicular subclavian artery cannulation for cerebral malperfusion in aortic dissection.

A patient with acute type A aortic dissection extending from the aortic root to the right common femoral artery presented with cerebral malperfusion.

Multimed Man Cardiothorac SurgNov 5, 2026Read case
Case ReportMedical Genetics

De novo SETD5 missense variants in individuals with MRD23 cluster within the protein's SET domain.

SETD5 heterozygous loss-of-function (LoF) variants and 3p25.3 deletions containing the SETD5 gene cause intellectual developmental disorder, autosomal dominant 23 (MRD23).

Hum GenetNov 5, 2026Read case
Case ReportNephrology

Vitamin D receptor activator-associated calcium-alkali syndrome-like phenotype without calcium supplementation: a case series of seven patients.

A retrospective series identified seven elderly women receiving vitamin D receptor activators who developed hypercalcemia, bicarbonate of at least 26 mmol/L, and acute kidney injury, meeting the study’s operational…

CEN Case RepNov 5, 2026Read case
Clinical ResearchUrology

Intravesical BCG-induced granulomatous prostatitis mimicking prostate cancer in patients with non-muscle invasive bladder cancer: a systematic review.

This systematic review examined the clinical presentation of granulomatous prostatitis associated with intravesical BCG therapy for non-muscle-invasive bladder cancer.

World J UrolNov 5, 2026Read summary
Clinical ResearchOncology (Medical)

Prognostic Value of the Preoperative Systemic Immune-Inflammation Index for Overall Survival After Surgical Resection for Gallbladder Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed whether preoperative systemic immune-inflammation index (SII) is associated with overall survival after gallbladder cancer resection.

J Gastrointest CancerNov 5, 2026Read summary
Clinical ResearchOncology (Medical)

A phase 1 study of 4'-thio-2'-deoxycytidine in patients with solid tumors.

This phase 1 dose-escalation study evaluated oral 4′-thio-2′-deoxycytidine (TdCyd) in adults with advanced solid tumors. Twenty-seven patients received treatment on days 1–5 and 8–12 of 21-day cycles.

Cancer Chemother PharmacolNov 5, 2026Read summary
Case ReportOphthalmology

Clinical Reasoning: A 68-Year-Old Woman With Bilateral Optic Disc Edema.

A 68-year-old immunocompetent woman presented with headache, vertigo, and diplopia. Examination revealed bilateral optic disc edema.

NeurologyNov 5, 2026Read case
Case ReportNephrology

Recovery after more than one month of dialysis in legionella-associated acute kidney injury: a case evaluated with gallium-67 scintigraphy and renal biopsy.

A 73-year-old man developed dialysis-dependent acute kidney injury during severe Legionella pneumonia. Although the infection resolved and antibiotics had been stopped, kidney injury persisted for more than a month.

CEN Case RepNov 5, 2026Read case
Clinical ResearchEmergency Medicine

Efficiency of Rescue Paramedic Hoist versus Underslung Antenna in Helicopter-Based Avalanche Searches: A Randomized Trial.

This randomized experimental field trial compared helicopter-based avalanche transceiver searches using an underslung antenna or a hoisted rescue paramedic with a handheld transceiver.

Prehosp Disaster MedNov 5, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Endoscopic dacryocystorhinostomy with versus without silicone intubation in chronic dacryocystitis: a comparative meta-analysis.

This systematic review and meta-analysis compared endoscopic dacryocystorhinostomy (EN-DCR) with versus without silicone intubation for chronic dacryocystitis.

Int OphthalmolNov 5, 2026Read summary
Case ReportOphthalmologyOpen access

STAT6-positive solitary fibrous tumour of the lacrimal gland with floret-type giant cells: a rare case report.

A 52-year-old man presented with five months of enlarging left lacrimal swelling, proptosis, and mildly reduced visual acuity. CT showed a well-defined 9 × 12 mm orbital lesion without bone erosion or local invasion.

BMC OphthalmolNov 5, 2026Read case
Case ReportOtolaryngology (ENT)

Acupoint-Propagated Sensation During Laser Acupuncture in Bell's Palsy.

Two patients with chronic Bell’s palsy received non-invasive laser acupuncture three times weekly. Assessment included facial nerve grading scales, electromyography, electroneurography, and blink reflex testing.

J Vis ExpNov 5, 2026Read case
Clinical ResearchUrology

Too good to be true? AI performance in CT-based urinary stone detection and classification: EAU endourology systematic review and diagnostic accuracy meta-analysis.

This systematic review and diagnostic accuracy meta-analysis assessed AI for detecting and classifying urinary stones on CT.

World J UrolNov 5, 2026Read summary
Case ReportOrthopedic Surgery

Anomalous Triceps Muscle Slip as an Unusual Cause of Ulnar Nerve Entrapment in a Division I Baseball Pitcher: A Case Report.

A 19-year-old right-hand-dominant collegiate pitcher developed medial elbow pain, reduced pitching velocity, and ulnar-sided numbness after a bullpen session.

JBJS Case ConnectNov 5, 2026Read case
Clinical ResearchRheumatology

Prevalence of generalized joint hypermobility, hypermobility spectrum disorders and Ehlers-Danlos syndrome: systematic review and meta-analysis.

This systematic review and meta-analysis assessed the prevalence of generalized joint hypermobility (GJH), hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).

Rheumatol IntNov 5, 2026Read summary
Case ReportInfectious Diseases

Cutaneous Aspergillosis Among Extremely Preterm Neonates in Neonatal Intensive Care Units - Michigan and New York, 2023-2024.

Cutaneous aspergillosis is a rare, life-threatening fungal infection in neonates, particularly those born extremely preterm (gestational age <28 weeks); outbreaks have been linked to environmental sources of Aspergillus…

MMWR Morb Mortal Wkly RepNov 5, 2026Read case
Clinical ResearchHematology

Combining quizartinib with intensive chemotherapy for older patients with newly diagnosed AML: results of the UK NCRI AML18 trial.

The multicentre randomised UK NCRI AML18 trial evaluated quizartinib after intensive chemotherapy, with or without maintenance, in patients older than 60 years with newly diagnosed AML or high-risk myelodysplastic…

BloodNov 5, 2026Read summary
Clinical ResearchPulmonologyOpen access

Effect of remote patient monitoring on PAP adherence and patient-reported outcomes in obstructive sleep apnea: a comparative study.

This prospective, open-label, active-comparator randomized trial compared remote patient monitoring (RPM) with standard care (SOC) in PAP-naive adults with obstructive sleep apnea who owned a smartphone.

Sleep BreathNov 5, 2026Read summary
Clinical ResearchGastroenterology

Clinical Evidence for Adding Chaiqin Chengqi Decoction to Acute Pancreatitis Care: A Systematic Review and Meta-analysis of Randomized Trials.

This systematic review and meta-analysis assessed randomized trials of Chaiqin Chengqi Decoction (CQCQD) added to conventional care for acute pancreatitis. Nineteen trials involving 1,824 participants were included.

J Vis ExpNov 5, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Syringomyelia secondary to degenerative spinal canal stenosis: a systematic review.

This PRISMA 2020 systematic review synthesised patient-level reports of syringomyelia associated with degenerative spinal canal stenosis, predominantly cervical spondylosis.

Neurosurg RevNov 5, 2026Read summary
Case ReportVascular Surgery

Occult Compression at the Pectoralis Minor-Second Rib Level After Cervical and First Rib Resection for Thoracic Outlet Syndrome: A Case Report.

A 29-year-old woman with neurogenic thoracic outlet syndrome associated with a cervical rib continued to have symptoms after supraclavicular cervical and first rib resection.

JBJS Case ConnectNov 5, 2026Read case
Case ReportNeurosurgery

Spontaneous Colonic Migration of a Ventriculoperitoneal Shunt Catheter.

A 63-year-old man developed fever, somnolence, and elevated inflammatory markers 2.5 years after ventriculoperitoneal shunt placement.

Am J Case RepNov 5, 2026Read case

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