Management of Bullous Pemphigoid and Norwegian Scabies with Dupilumab Plus Ivermectin.
Yanli Zhang, Yuting Liu, Hengan Yi
✦ AI-curated · Sources linked
Case in brief
An elderly patient had bullous pemphigoid alongside Norwegian scabies, a rare comorbidity. Because systemic corticosteroids pose substantial risks in older patients, treatment began with a low-to-moderate corticosteroid dose. The patient then achieved complete remission with combination therapy using dupilumab, which targets interleukin-4/13 signaling, and ivermectin.
What made this case unusual
The case combined bullous pemphigoid with Norwegian scabies and achieved complete remission with dupilumab plus ivermectin after initial low-to-moderate-dose corticosteroid treatment.
Diagnostic / clinical pearl
When bullous pemphigoid coexists with Norwegian scabies in an elderly patient, this report describes remission after initial corticosteroid induction followed by dupilumab and ivermectin.
Why it matters
The case suggests a potential corticosteroid-sparing approach for this comorbidity in patients at high risk from systemic corticosteroids.