Sutureless versus renorrhaphy in robot-assisted off-clamp partial nephrectomy: a systematic review and meta-analysis.
Xiaofu Zeng, Xiaofeng Xu, Jingxian Luo et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the outcomes of sutureless versus conventional renorrhaphy in robot-assisted off-clamp partial nephrectomy (RAPN) across four studies with 787 patients. The analysis found no significant difference in Trifecta achievement (RR 1.17, 95% CI 0.97-1.41), indicating that sutureless techniques may be noninferior to traditional methods without demonstrating superiority.
Key findings
- No significant difference in Trifecta achievement between sutureless and conventional renorrhaphy (RR 1.17, 95% CI 0.97-1.41).
- The sutureless approach showed a smaller perioperative eGFR decline (MD -3.89, 95% CI -6.16 to -1.62).
- The randomized controlled trial indicated noninferiority of the sutureless approach (RR 0.97, 95% CI 0.92-1.04).
- No significant differences in major complications, blood transfusion, or positive surgical margins were observed.
Why it matters
Understanding the comparative effectiveness of sutureless versus conventional renorrhaphy can inform surgical decision-making in partial nephrectomy, potentially leading to improved patient outcomes and reduced complications.
What to keep in mind
The study's findings are limited by substantial heterogeneity and potential biases in propensity score-matched studies.