Topical Carboxytherapy as an Adjunct to Skin Recovery Post-CO2 Laser Fractional Resurfacing.
J Drugs DermatolSep 1, 2026
Clinical ResearchDermatology
Barbara Hernandez-Rovira, Emma Villamaria, K-Raman Purushothaman et al.
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In 30 seconds
This randomized controlled trial evaluated the effectiveness of topical carboxytherapy in enhancing skin recovery after fractional CO2 laser resurfacing in six females with mild-to-moderate photoaging. The study found that topical carboxytherapy significantly improved healing and aesthetic outcomes compared to standard care, with notable histological changes observed at week 4.
Key findings
- Topical carboxytherapy accelerated erythema resolution compared to placebo.
- Transepidermal water loss normalized more rapidly with carboxytherapy.
- Histological analysis showed epidermal thickening and rete ridge formation at week 4.
- Investigator ratings indicated significantly improved healing and aesthetic outcomes.
Why it matters
Understanding adjunctive treatments like topical carboxytherapy can enhance recovery protocols following laser procedures, potentially leading to better patient satisfaction and outcomes in dermatological practice.