Management considerations of ameloblastic carcinoma in soft-tissue: case report and literature review.

Oral Surg Oral Med Oral Pathol Oral RadiolJul 1, 2026 (epub)
Case ReportOncology (Medical)

Padmaraj Hegde, Kritharth Sujith, Lida Mary Nidhin Philip

✦ AI-curated · Sources linked

Case in brief

A 36-year-old woman with a history of mandibular ameloblastoma underwent segmental mandibulectomy and reconstruction. Three years later, she presented with a submental swelling, which was initially diagnosed as recurrent follicular ameloblastoma. However, further histopathological analysis post-surgery revealed ameloblastic carcinoma. The patient received complete excision and neck dissection, and is under close surveillance for potential adjuvant therapy.

Diagnostic / clinical pearl

Clinicians should be aware that ameloblastic carcinoma can arise from previously treated ameloblastoma, presenting as soft-tissue recurrence and complicating management.

Why it matters

This case highlights the importance of thorough histopathological evaluation in cases of recurrent ameloblastoma, as malignant transformation can occur, necessitating a comprehensive treatment approach.

Source

PubMed · PMID 42562755

Published in Oral Surg Oral Med Oral Pathol Oral Radiol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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