Comparative Efficacy of Non-Pharmacological Multicomponent Interventions in Community-Dwelling Older Adults With Frailty or Prefrailty: A Systematic Review and Network Meta-Analysis.

Int J Older People NursSep 1, 2026
Clinical ResearchGeriatricsOpen access

Huanyu Gao, Xuan Li, Minmin Leng et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and network meta-analysis evaluated the efficacy of non-pharmacological multicomponent interventions in community-dwelling older adults with frailty or prefrailty. Twenty-two randomized controlled trials were analyzed, revealing that the combination of exercise and cognitive intervention ranked highest for reducing frailty levels (SUCRA = 84.7%).

Key findings

  • Exercise + cognitive intervention had the highest efficacy for reducing frailty levels (SUCRA = 84.7%).
  • Exercise + cognitive + social support intervention ranked second (SUCRA = 83%).
  • Exercise + nutrition + psychological intervention was most effective for improving motor ability (SUCRA = 77.1%).

Why it matters

Understanding the most effective non-pharmacological interventions for frailty can guide clinicians in developing targeted care plans, ultimately improving the quality of life for older adults and reducing caregiver burden.

Source

PubMed · PMID 42547949Free full text on PubMed Central

Published in Int J Older People Nurs. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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