[Translated article] Safety of excipients in pediatric medications: impact on child health.

Farm HospJun 24, 2026 (epub)
Clinical ResearchPediatrics

Leonel Silva-Chocoteco, Monserratt Abud-González, Cesar Ricardo Cortez-Álvarez et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review evaluated the safety of excipients in pediatric medications, highlighting their potential toxicity in children. The review identified 54 excipients with documented risks, including hepatic, renal, and neurological toxicity. The findings emphasize the need for improved safety evaluations and age-specific formulations due to children's heightened vulnerability.

Key findings

  • Fifty-four excipients with potential toxicity in children were identified and classified into four functional groups.
  • Notable adverse effects include hepatic, renal, and neurological toxicity, as well as hypersensitivity reactions.
  • A significant limitation is the lack of specific data for the pediatric population.

Why it matters

Understanding the safety of excipients is crucial for pediatric care, as children are more susceptible to adverse effects. This knowledge can guide healthcare professionals in making informed decisions regarding medication formulations.

Source

PubMed · PMID 42342537

Published in Farm Hosp. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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