Associations Between Weight Loss Prior to Knee and Hip Arthroplasty and Peri- and Post-Operative Outcomes: A Systematic Review and Meta-Analysis.

Obes RevMay 12, 2026 (epub)
Clinical ResearchOrthopedic Surgery

Moneet Gill, Tim Lindsay, Daniel Kevin Llanera et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis assessed whether weight loss before knee or hip arthroplasty was associated with better short-term outcomes in people with obesity. It included 21 articles comparing patients with BMI > 30 kg/m² who lost weight before surgery with those who did not, examining outcomes within 90 days. Preoperative weight loss was associated with higher odds of revision surgery (OR 1.37 [1.01-1.84], p = 0.04). It was not associated with altered risks of deep vein thrombosis, pulmonary embolus, or superficial or deep wound infection.

Key findings

  • Pre-arthroplasty weight loss was associated with increased 90-day revision risk (OR 1.37 [1.01-1.84], p = 0.04).
  • Weight loss did not alter postoperative risks of deep vein thrombosis or pulmonary embolus.
  • Weight loss did not alter risks of superficial or deep wound infection.

Why it matters

The findings challenge the assumption that preoperative weight loss necessarily reduces short-term complications after lower limb arthroplasty in people with obesity. The observed association with revision warrants attention, but the review does not establish that weight loss causes this outcome. Better prospective evidence is needed to inform guidance on weight management before arthroplasty.

What to keep in mind

The review calls for large, well-designed prospective studies, indicating that the available evidence is not robust enough to support definitive guidance.

Source

PubMed · PMID 42124368

Published in Obes Rev. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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