Recruitment of Minority Patients in Metabolic Dysfunction-Associated Steatotic Liver Disease Clinical Trials.

Dig Dis SciMay 6, 2026 (epub)
Clinical ResearchGastroenterologyOpen access

Sarah E Park, Yael Wollstein, Alan L Hutchison et al.

✦ AI-curated · Sources linked

In 30 seconds

This meta-analysis examined racial and ethnic diversity in 91 randomized controlled trials of metabolic dysfunction-associated steatotic liver disease (MASLD) therapies conducted in the US and Canada from 2005 to 2024. The study found that 78.8% of participants were White, while only 31.7% were Hispanic, despite the latter group being disproportionately affected by MASLD.

Key findings

  • 78.8% of trial participants were White, 6.2% Asian, 2.5% Black, and 31.7% Hispanic.
  • Hispanic enrollment in trials increased from 20.3% (2009-2014) to 40.0% (2020-2024).
  • Only 61.5% of studies included ethnicity data.

Why it matters

Understanding the racial and ethnic composition of clinical trial participants is crucial for ensuring that findings are generalizable and applicable to diverse populations, particularly for conditions like MASLD that disproportionately affect certain groups.

Source

PubMed · PMID 42090052Free full text on PubMed Central

Published in Dig Dis Sci. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Gastroenterology

Clinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Nutr RevNov 12, 2026Read summary
Clinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

N Engl J MedNov 12, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.