Primary cutaneous epithelioid hemangioendothelioma of the temporal region: a case report.
Xinrong Chen, Yusa Chen, Yuehuan Bian
✦ AI-curated · Sources linked
Case in brief
A 70-year-old female presented with a progressively ulcerated plaque on her left temple. Histopathological analysis confirmed primary cutaneous epithelioid hemangioendothelioma (EHE) through characteristic features and strong immunohistochemical expression of CD31 and ERG. Systemic evaluation showed no extracutaneous disease. The patient opted against surgery for aesthetic reasons and has been monitored every three months, with no disease progression noted over six months.
What made this case unusual
The primary cutaneous manifestation of epithelioid hemangioendothelioma in the head and neck region is exceptionally rare, making this case noteworthy.
Diagnostic / clinical pearl
Clinicians should consider cutaneous epithelioid hemangioendothelioma in the differential diagnosis of persistent ulcerative facial lesions, emphasizing the importance of early histopathological evaluation.
Why it matters
Recognizing EHE early can lead to effective management, including surgical excision of localized lesions, which can achieve cure while preserving aesthetics.