Total Knee Arthroplasty in Postpolio Residual Paralysis: A Systematic Review and Pooled Analysis of Its Outcomes and Complications.

J ArthroplastyMar 11, 2026 (epub)
Clinical ResearchOrthopedic Surgery

Anil Regmi, Surakshya Baral, Ravi Saini et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and pooled analysis assessed complications and revision after total knee arthroplasty (TKA) in patients with postpolio residual paralysis. It included 12 studies comprising 272 knees. The pooled overall complication rate was 16% (95% CI, 9 to 26), and revision surgery occurred in 8% of knees (95% CI, 4 to 15). Instability or residual recurvatum and periprosthetic fracture were the most common reported complications. Outcomes varied across studies, with moderate-to-high heterogeneity for complications and revisions.

Key findings

  • Across 12 studies and 272 knees, the pooled complication rate was 16% (95% CI, 9 to 26).
  • Revision surgery occurred in 8% of knees (95% CI, 4 to 15).
  • Instability or residual recurvatum occurred in 5%, and periprosthetic fractures in 2%.
  • Heterogeneity was moderate to high for complications and revisions (I 2 = 58 to 72%, P ≤ 0.01).

Why it matters

TKA can provide satisfactory outcomes in patients with postpolio residual paralysis, but the pooled findings indicate meaningful risks of complications and revision. Instability, recurvatum, and periprosthetic fracture are particularly relevant when considering expected outcomes and planning surgery. Variation across the included cohorts also means pooled estimates should be interpreted in light of differing reported outcomes.

What to keep in mind

The analysis pooled 12 studies with moderate-to-high heterogeneity in complications and revisions, indicating variability across cohorts.

Source

PubMed · PMID 41825494

Published in J Arthroplasty. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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